Báo cáo khoa học: Mutants of Saccharomyces cerevisiae deficient in acyl-CoA synthetases secrete fatty acids due to interrupted fatty acid recycling docx

... Authors Journal compilation ª 2008 FEBS Mutants of Saccharomyces cerevisiae deficient in acyl-CoA synthetases secrete fatty acids due to interrupted fatty acid recycling Michael Scharnewski 1 , Paweena ... certain pools of fatty acids. To assess the role of acyl-CoA synthetases in regu- lating particular pools of fatty acids, we used mutan...

Ngày tải lên: 07/03/2014, 05:20

... Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; has a role in localization of Bcy1p, a regulatory subunit of protein kinase A; implicated in ... respiratory chain complexes. The next possibility is that the protein of interest is involved in the transport of exogenous CoQ from the extracellular medium into the cell and on...

Ngày tải lên: 06/03/2014, 11:20

... 17.6 Fig. 5. Insertion of stefins into DOPC and DOPG monolayers. (A) Kinetic traces of the insertion into DOPG lipid monolayers at initial pressure of 5 mNÆm )1 . The proteins were injected into the ... for some proteins that bind specifically to membranes, such as the small membrane-binding domains involved in cell signaling [39,40] or domains used by pore-form- ing toxins for attach...

Ngày tải lên: 07/03/2014, 17:20

... ring contraction involves the migration of ring A after for- mation of the d-lactone from the ring A acetate group to C20, following the methylation of Co-precorrin-3 at C17 [6,7]. In the aerobe Pseudomonas ... feeding experiments with d-amino[1- 13 C]levulinic acid (a biosynthetic intermediate of tetra- pyrrole) and d-amino[1- 13 C,1,1,4- 18 O 3 ]levulinic acid in combinati...

Ngày tải lên: 23/03/2014, 09:20

... helix–span–helix domain at the C-terminus shown in blue medi- ates dimerization and, together with the basic domain, (red) DNA-binding. ‘*’, amino acids that are identical in all sequences in the align- ment; ... role of AP-2a and AP-2e in chondrogenesis. Overview of the differen- tiation stages during chondrogenesis and the involvement of transcription factors (henatoxylin an...

Ngày tải lên: 16/02/2014, 09:20

... appears to be sufficient to inhibit lysosomal degradation of modified proteins. Interestingly, apoB from oxidized LDL has been shown to accumulate in secondary lysosomes in macrophages because of inefficient ... and either a mAb to CD36 [47], the SR-A inhib- itor fucoidin, or AGE–HSA, which is known to bind to RAGE [48]. The inhibition of uptake observed with the mAb to C...

Ngày tải lên: 19/02/2014, 02:20

... modifica- tions. Total lysates were obtained by boiling 10 min in phosphate-buffered saline containing 0.5% SDS and 1.0% 2-mercaptoethanol, and spinning at 12 000 r.p.m. for 10 min. The clean supernatants ... with a linearized plasmid containing a 553-bp fragment of b3Gal-T5 cDNA, that includes the initial 360 bp of the coding sequence and 192 bp of the 5¢ untranslated region of the...

Ngày tải lên: 19/02/2014, 12:20

... corresponding to nouns, because our system makes little use of hierarchical information about other parts of speech.' There are about 60,000 of these noun concepts in WordNet, including ancestor ... assumptions for all linguistic information, to be described later. There are four linguistic servers, corresponding to the four major categories of lexical information...

Ngày tải lên: 20/02/2014, 18:20

... property of the N-linked chains of bovine zona proteins is due to sialic acids [14], whereas many sulfates are linked to the N-acetyllactosamine repeats of porcine zona proteins [7,24]. The N-linked ... (sialidase digests of the acidic fraction in Table 1) were found in this analysis of ZPA. These sialic acids must be linked to the nonreducing terminal b-Gal residues...

Ngày tải lên: 21/02/2014, 03:20

... 37–357 C-terminal extension amino acids 358–518 Copper binding motif Arg40 Phe453 Cys84 Tyr349 Tyr347 Copper binding motif Pro-tyrosinase 481 amino acids Core domain 36–357 C-terminal extension amino ... Determination of the mass of the proteins by MS revealed masses of 36 506 kDa (recombinant core tyrosinase) and 37 874 kDa (trypsinized pro-tyrosi- nase) corresponding to a...

Ngày tải lên: 06/03/2014, 11:20