Báo cáo khoa học: Many fructosamine 3-kinase homologues in bacteria are ribulosamine⁄erythrulosamine 3-kinases potentially involved in protein deglycation docx

... Journal compilation ª 2007 FEBS Many fructosamine 3-kinase homologues in bacteria are ribulosamine ⁄ erythrulosamine 3-kinases potentially involved in protein deglycation Rita Gemayel, Juliette ... & Van Schaftingen E (2003) A mammalian protein homo- logous to fructosamine- 3-kinase is a ketosamine-3- kinase acting on psicosamines and ribulosamines but not o...

Ngày tải lên: 07/03/2014, 05:20

... PilA4 competence proteins and raised antisera against these proteins to visualize the proteins in the T. thermophilus wild-type strain. This is the first report on the detection of competence proteins in T. ... fatty acylation and, thereby, be involved in membrane anchoring of the pilin. Since PilA4 is similar to the meningococcal pilin and contains several central serine residues, it...

Ngày tải lên: 07/03/2014, 12:20

... C-terminal hydrophobic area of the 4-kDa peptide plays an important role in binding to the 43-kDa protein. Keywords: hormone-like peptide; receptor-like protein; protein protein interaction; alanine-scanning ... receptor-binding area are shown in red, and the residues important for the direction to insulin receptor are shown in orange (D and E). In (F), four residues in red...

Ngày tải lên: 17/03/2014, 03:20

... constructed. An alanine residue was inserted after Phe18 in order to disrupt a helix–helix packing interface involving the amino- acid residues on both sides of the insertion [40]. In the other two ... membrane-spanning segment of the b-subunit (subunit 4) and (b) inter-ATP synthase cross-linking with a bis-maleimide reagent and involving a cysteine residue introduced into the C-terminal...

Ngày tải lên: 31/03/2014, 01:20

... hypotheses are now being tested. Recently, viroporins of RNA viruses (such as 6K protein of Sindbis virus, E protein of mouse hepatitis virus, M2 protein from in uenza A, 2B and 3A pro- teins of ... MPyV, lacking both minor proteins. Results Individual expression of the minor capsid proteins (VP2 or VP3) Attempts to transiently express individual MPyV struc- tural proteins VP2 or VP3...

Ngày tải lên: 16/02/2014, 09:20

... triglyceride, glucose, leptin and insulin, and insulin sensitivity, in TG mice After 6 weeks of normal or HF diet, serum levels of triglyceride, glucose, leptin and insulin were deter- mined (Fig. 4A). ... PPARc in WAT, it is possible that PGD 2 stimulates pancreatic islets to increase insulin secretion. Indeed, serum insulin levels were increased after treatment with thiazolidinediones...

Ngày tải lên: 16/02/2014, 09:20

... two mutants in bacterial clearance might reflect differences in the integrity of their outer membrane, binding activity and sensitivity of the murine comple- ment-mediated killing. In conclusion, ... deduced proteins were performed using tmpred, toppred and pre- dictprotein [43–45]. Similarities of these two proteins with late acyltransferase homologs in several other Gram-nega- tive...

Ngày tải lên: 18/02/2014, 14:20

... both of the fusion proteins containing C-terminal deletions show reduced sorting efficiency as compared to protein containing the intact 38 amino acid domain (Fig. 2B,C, compare 878–906 and 878–891 ... the native proteins. a-Helical sequences involved in sorting proteins to secretory granules have also been observed in other proteins: prosomatostatin contains an a-helix in its N-term...

Ngày tải lên: 18/02/2014, 16:20

... tyrosine phosphatase-like phytase; P-loop, phosphate-binding loop; PTP, protein tyrosine phosphatase; RPTPa, receptor protein tyrosine phosphatase alpha; Yop51, Yersinia protein tyrosine phosphatase. FEBS Journal 275 ... loop in PhyAsr cannot undergo an open-to-close movement upon substrate binding, due to the presence of a small b-barrel domain that is unique to this protein and is...

Ngày tải lên: 18/02/2014, 18:20

... phosphatidyl- ethanolamine-binding protein; PG, phosphatidylglycerol; PS, phosphatidylserine; PtdIns, phosphatidylinositol; PtdIns(3)P, phosphatidylinositol 3-phosphate; PtdIns(4)P, phosphatidylinositol 4-phosphate; ... suggest that the N-terminal segment (Met1–His18) in its carboxypeptidase Y-binding sites is involved in the specific and efficient binding to anionic phospholipid membran...

Ngày tải lên: 19/02/2014, 05:20