Báo cáo khoa học: Energetic and metabolic transient response of Saccharomyces cerevisiae to benzoic acid docx

... FEBS 5541 Energetic and metabolic transient response of Saccharomyces cerevisiae to benzoic acid M. T. A. P. Kresnowati*, W. A. van Winden, W. M. van Gulik and J. J. Heijnen Department of Biotechnology, ... (2001) Genetic manipulation of 6-phosphofructo-1-kinase and fructose 2,6-bisphosphate levels affects the extent to which benzoic acid inhibits the growt...

Ngày tải lên: 07/03/2014, 04:20

... FEBS as standards. Figure 2B shows that the elution time of Hep-dW4 is identical to that of the VIH II fragment. By MALDI-TOF MS, the mass of this fragment was found to be 795.8 Da, similar to the ... 41 Fig. 1. RP-HPLC profile of an acetic acid extract of 30 lobster sinus glands. Only the part of the chromatogram where CHHs and VIHs are eluted is shown. The nature of...

Ngày tải lên: 18/02/2014, 11:20

... model of the PDGF-C growth factor domain indicates the disulfide bridges in PDGF-C to consist of Cys250 and 294, Cys280 and 335, and Cys287 and 337, and the inter- monomeric bonds to consist of Cys274 ... loops 1, 2 and 3 (Fig. 3A), and due to the head -to- tail arrangement, loop 2 of one monomer will be close to loops 1 and 3 of the other monomer when the dim...

Ngày tải lên: 19/02/2014, 07:20

... D esign and synthesis of a p otent c yclic ana- logue of the myelin basic p rotein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental ... the design of synthetic p eptides and nonpeptide mimetics that c an act as vaccines o r artificial regulators of the immune response. Linear and c yclic analogues of se...

Ngày tải lên: 07/03/2014, 16:20

... concentration of 50 mgÆL )1 [20,21]. The purification procedure was similar to that of the wild-type enzyme, but 3 m M dithiothreitol was added to all buffers and solutions to avoid oxidation of the incorporated ... factor of 18.8% and an R free of 22.3% with over 90% of the residues in the most favored region of a Ramachandran plot (Table 2). The resulting model is dep...

Ngày tải lên: 08/03/2014, 02:20

... 2011 Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein Erik Lundberg 1 , Anders Olofsson 2 , Gunilla T. Westermark 3 and ... seem to be functional and to influence aging in C. elegans, and are referred to as TRPs [69]. TTR-1 to TTR-57 are, however, not related to the YRGS TRP family [19],...

Ngày tải lên: 16/03/2014, 01:20

... designed in order to confirm the functional importance of D31 and L32 as substrate-binding, cofactor-binding and inhibitor- binding sites. The objectives of this study were to: (a) utilize site- directed ... of aspartate 27 of dihydrofolate reductase from Escherichia coli in interconversion of active and inactive enzyme conformers and binding of NADPH. J Biol Chem 265, 5...

Ngày tải lên: 16/03/2014, 10:20

... from tongue to stomach, but not in small and large intes- tines. Adh3 shows low and ubiquitous expression in all tissues and Aldh1 is observed at low to moderate levels in esophagus, stomach and jejunum, ... related members of the ADH family. In both mice and rats, Adh4 is transcribed in the epithelium of tongue, esophagus and stomach, whereas Adh1 was active from stomach...

Ngày tải lên: 16/03/2014, 11:20

... the professors directly to me and two directed to my team. (3) I found that I spent most of my time learning from my fellow students. (4) A standard response from my professors would be that of a ... in- tensity), and to link it to the target and the holder. Figure 2 presents the expression level scheme. At this stage, annotators mark text spans, and are allowed to ass...

Ngày tải lên: 16/03/2014, 23:20

... Structural and functional insights into RAGE activation by multimeric S100B. EMBO J 26, 3868– 3878. 12 Donato R (2007) RAGE: a single receptor for several ligands and different cellular responses: ... are implicated and display marked changes in their expression levels in many types of cancer, neurodegenerative disorders, inflammatory and autoim- mune diseases. The structure and fu...

Ngày tải lên: 23/03/2014, 03:20