Báo cáo khoa học: Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes ppt

... Authors Journal compilation ª 2008 FEBS 131 Proteomic analysis reveals Hrs ubiquitin- interacting motif-mediated ubiquitin signaling in multiple cellular processes Julia W. Pridgeon*, Elizabeth A. ... and ubiquitin binding of the ubiquitin- interacting motif. J Biol Chem 278, 28976–28984. 12 Miller SL, Malotky E & O’Bryan JP (2004) Analysis of the role of...

Ngày tải lên: 07/03/2014, 03:20

... expression pattern of cellular proteins in the human catecholaminergic neuroblastoma cell line SH-SY5Y, overexpressing a-synuclein. A proteomic analysis is expected to identify cellular alterations that ... dopamine treatment, overexpres- sion of a-synuclein significantly affected the levels of four proteins [stathmin 1, glutathione S-transferase (GST)p, Ran 1 binding protein and C1q...

Ngày tải lên: 15/02/2014, 01:20

... PowerBlot analysis showed altered expression of many proteins involved in apoptosis, including the expression profiles of proteins involved in the mito- chondrial (bcl-2, bax, and bcl-x, etc.) and ... As shown in Fig. 3, 12hr exposure to hypoxia caused almost no increase in the phosphory- lated JNKs protein level in the cell line. Twenty-four-hour exposure to hypoxia resulted...

Ngày tải lên: 31/10/2012, 15:12

... points in F-measure. The fourth line in Tables 6 shows that transformation rules significantly contributed to im- proving the accuracy. Considering the results obtained in this section and in ... morphemes in as- cending order of their probabilities as estimated by the proposed models. In our experiments, only the information con- tained in the corpus was used; however, more appr...

Ngày tải lên: 17/03/2014, 06:20

... protein fun ction in other genes where it can in uence many cellular processes including signal transduction, transcriptional regulation, cellular transformation and subcellular l ocalization in ... Accord- ingly, the majority of alterations in 63 kDa protein mass in multiple cellular contexts identified here in are mediated predominantly by transcriptional r egulation. We...

Ngày tải lên: 19/02/2014, 16:20

... residue-long proteins lacking disulfide bridges. Type II cystatins, cystatins C, D, E ⁄ M, F, S, SA, SN are longer extra- cellular proteins, consisting of % 120 amino acid resi- dues and containing two ... bridges. Type III cystatins, the kininogens, are large multifunctional plasma proteins, containing three type II cystatin-like domains. Cystatin F was discovered recently by three inde- pe...

Ngày tải lên: 19/02/2014, 17:20

... Extraction in the Fast Lane Marius Pas¸ca Google Inc. Mountain View, CA 94043 mars@google.com Dekang Lin Google Inc. Mountain View, CA 94043 lindek@google.com Jeffrey Bigham ∗ University of Washington Seattle, ... NNP IN NNP NNP VBD VBN NNP CD , CD . Infix foundfound Chester Burton Atkins was born June 20 , 1924 , on a farm near Luttrell . NNP NNP NNP VBD VBN NNP CD , CD , IN DT NN IN...

Ngày tải lên: 20/02/2014, 12:20

... donor of propylamine groups in the metabolism of spermidine and spermine [2] and an intermediary in the trans-sulfuration pathway to cysteine, one of the three amino acids involved in glutathi- one ... cysteine compositions in the central domain lack the homologous mammalian enzyme amino acids at positions 61 and 69 which are, in turn, involved in establishing the disulfide bond an...

Ngày tải lên: 08/03/2014, 08:20

... its success. In our case, if we look at affect (FAH) or attitude (CERT) in isolation we find many interactions; in contrast, combining them offers little insight. 6 Results – insights & ... ‘Certain’ and ‘Anything Else’ (in this case Uncertain, Mixed and Neutral). By studying the dependency between binary variables we can understand how the interaction works. Table 2 report...

Ngày tải lên: 17/03/2014, 04:20

... brain abundant myri- stoylated protein localized at the inner surface of the presynaptic plasma membrane. Emerging evidence suggests that BASP1 is critically involved in various cellular processes, ... presum- ably involves the regulation of actin cytoskeleton dynamics through either direct interaction with actin- binding proteins [30] or modulation of the plasmalemmal distribution of ph...

Ngày tải lên: 28/03/2014, 23:20