Báo cáo khoa học: Increased susceptibility of b-glucosidase from the hyperthermophile Pyrococcus furiosus to thermal inactivation at higher pressures pptx

... Increased susceptibility of b-glucosidase from the hyperthermophile Pyrococcus furiosus to thermal inactivation at higher pressures Marieke E. Bruins 1 , Filip ... be a cause of inactivation at higher pressures. No dissociation into subunits was observed. One similar example from the literature showed that inactivation of the dimeric almond b-...

Ngày tải lên: 07/03/2014, 03:20

... Whereas the amounts of total and phosphory- lated c-Fos increased in the presence of ATZ + mer- captosuccinic acid, there was no change in the levels of total and phosphorylated c-Jun throughout the ... LMW-PTP [13]. The cysteines in the active sites of these phosphatases are easily inactivated by ROS, resulting in activation of the ERK pathway [14]. However, factors...

Ngày tải lên: 06/03/2014, 00:21

... conformational states of the monomeric form of the enolase. A schematic representation of the dissoci- ation and association of r-Pfen is presented in Scheme 1, where M nt is the native monomer, ... representation of dissociation of the dimeric (D) form of enolase to the imidazole-induced and pH-induced mono- meric (M im or M pH ) forms. The dimer is shown to d...

Ngày tải lên: 23/03/2014, 09:20

... than hepatocytes from 11–13-week-old male rats. Expression of glycogen-targeting proteins in hepatocytes from fa ⁄ fa rats To test whether the defect in hepatocytes from fa ⁄ fa rats is associated ... phosphorylase-a and glycogen synthesis in hepatocytes from fa⁄ fa rats by modulating the concentration of phosphorylase-a. Treatment of hepatocytes from fa ⁄ fa rats and Fa...

Ngày tải lên: 30/03/2014, 11:20

... details of these signaling events have yet to be investigated, many of the molecular interactions down- stream of the Eph and ephrin molecules appear to lead to the regulation of the cytoskeleton of ... recently, the Src family kinases (SFKs) and the PTP-BL phosphatase were proposed to be mediators of the phosphorylation state of the cytoplasmic domain o...

Ngày tải lên: 19/02/2014, 12:20

... function of the instability of the 70 kDa subunit. Obviously, the D subunit is a substrate of the I subunit, which led to questions concerning the assembly of the I and D building blocks into the ... studies of deuteroporphyrin IX to the H-subunit show a K d value of 0.53–1.2 l M [5]. The large subunit has therefore been suggested to be the catalytic subu...

Ngày tải lên: 19/02/2014, 12:20

... glycolysis, the TCA cycle, the oxidative limb of the pentose phos- phate pathway (OPPP), the urea cycle. However, these investigations do not provide data that can be used to calculate the fraction of the ... Also these data by themselves do not allow us to calculate the fraction of the flux that is channeled. The first additional requirement is to show that the...

Ngày tải lên: 19/02/2014, 18:20

... unwise to eliminate them at this point in the research. What is indicated, perhaps, is the structural classification of the weak suffixes by degree of weakness as a means of approaching the suffix-in- ... all the affixes could not be ex- pected to show up in two-vowel-string words. This paper summarizes the results of applying a modified form of the operation...

Ngày tải lên: 19/02/2014, 19:20

... FEBS reach saturation for HSA concentrations well lower than in the absence of myristate. This indicates that binding of myristate to the modulatory site also increa- ses the affinity of Mn(III)heme ... coordinated to the metal ion or bound to the protein in close proximity of the paramagnetic center the dipolar interaction is modu- lated by the reorientation of...

Ngày tải lên: 20/02/2014, 02:22

... BP800, Helsinki, Finland). The growth rate was cal- culated as the ratio of the absorbance of the experimental well to that of a blank well, and the IC50 was also calculated. Hoechst stain Cells ... medulloblastoma cells, perhaps because of the methylation of the promoter, and restoration of DKK1 expression can induce apoptosis and suppress colony formation [42]. A...

Ngày tải lên: 06/03/2014, 22:21