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Báo cáo khoa học: Functional classification of scaffold proteins and related molecules pptx

Báo cáo khoa học: Functional classification of scaffold proteins and related molecules pptx

Báo cáo khoa học: Functional classification of scaffold proteins and related molecules pptx

... MINIREVIEW Functional classification of scaffold proteins and related molecules La´szlo´Buday1,2 and Pe´ter Tompa11 Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, ... PDZ domains, and bindsa variety of receptors ⁄ channels, cytoskeletal and Table 1. Scaffold proteins and their kin. Representatives of the four categories of scaffold proteins and their relatives ... [19]. Classification of scaffolds and itslimitationsThe functions of the above four closely related catego-ries of signaling regulatory proteins show significantsimilarities and overlap (Fig. 1 and...
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Báo cáo khoa học:

Báo cáo khoa học: "Collective Classification of Congressional Floor-Debate Transcripts" ppt

... label of o and its observed attributes; (2) the cor-relations between the label of o and the observed at-tributes and labels of nodes connected to o; and (3)the correlations between the label of ... describe related work (Section 5) and offer analysis and conclusions (Section 6).2 Task Definition2.1 Collective Classification Given a network and an object o in the network,there are three types of ... ar-ticles (Yang and Liu, 1999), sentiment classifica-tion of movie reviews (Pang et al., 2002), and satire classification of news articles (Burfoot and Baldwin,2009). This and other work has...
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Báo cáo khoa học:

Báo cáo khoa học: "Automatic Classification of Verbs in Biomedical Texts" potx

... match between thevalues of K and the number of classes at the par-ticular level of the gold standard is the closest.IB is clearly better than ID at all levels of goldstandard. It yields its ... precision of clusters and ACC the recall. We define an F mea-sure as the harmonic mean of mPUR and ACC:F =2 · mPUR · ACCmPUR + ACCThe statistical significance of the results is mea-sured by randomisation ... target classification and a general lan-guage classification, we examined the extent towhich individual verbs and their frequencies dif-fer in biomedical and general language texts. We346 PROTEINS: ...
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Báo cáo khoa học:

Báo cáo khoa học: "Hedge classification in biomedical texts with a weakly supervised selection of keywords" doc

... results for hedge classification as a standalone task. In experimentswe made use of the hedge classification dataset of scientific texts provided by (Medlock and Briscoe,2007) and used a labeled ... data.• The extension of the feature representationused by previous works with bigrams and tri-grams and an evaluation of the benefit of usinglonger keywords in hedge classification. • We annotated ... stopwords). The automatic elimination of these irrelevant candidates is one of our main goals(to limit the number of candidates for manual con-sideration and thus to reduce the human effort re-quired...
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Tài liệu Báo cáo khoa học: Direct identification of hydrophobins and their processing in Trichoderma using intact-cell MALDI-TOF MS docx

Tài liệu Báo cáo khoa học: Direct identification of hydrophobins and their processing in Trichoderma using intact-cell MALDI-TOF MS docx

... 2. Intact-cell MALDI-TOF mass spectra of mycelia and spores of Trichodermastrains. The masses 7347 and 7494 of T. atroviride spores correlate with two proc-essed products of the spore hydrophobinSRH1 ... 7232 and 7237 in (A) and (E), or 7509 and 7514 in (A) and (C). An obvious shift is the appearance of higher mass peaks upon sporulation, presum-ably related to the only large hydrophobin of H. ... limited set of no more than six small proteins; (b)known cleavage sites of signal peptidases and fungalKex2-like proteinases; and (c) actual structural studies of H. jecorina HFB1 and HFB2.In...
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Báo cáo khoa học: Molecular identification of monomeric aspartate racemase from Bifidobacterium bifidum pptx

Báo cáo khoa học: Molecular identification of monomeric aspartate racemase from Bifidobacterium bifidum pptx

... was dissolved in 20 lLof8Murea and incubated at 37 °C for 1 h. To the solution, 60 lL of 0.2MTris/HCl buffer (pH 9.0) and 5 pmol of lysylendopeptidase were added, and the m ixture was incubated ... 210 nm of the effluent was monitoredcontinuously. The peptides were isolated and lyophilized.Amino acid sequence analysisThe N-terminal amino acid sequence of the enzyme and thesequences of the ... 7.0–7.5 and 45 °C.CofactorsThe enzyme did not require PLP as a coenzyme and w as notinhibited by 10 mMhydroxylamine and 1 mMphenylhydr-azine. The e nzyme was not affected by 10 mMEDTA and 1mMFAD,...
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Báo cáo khoa học:

Báo cáo khoa học: "Distributional Identification of Non-Referential Pronouns" pdf

... one of the most frequent words inthe English language, accounting for about 1% of tokens in text and over a quarter of all third-personpronouns.1Usually between a quarter and a half of it ... pio-neering work of Paice and Husk (1987), the inclu-sion of non-referential it detection in a full anaphoraresolution system by Lappin and Leass (1994), and the machine learning approach of Evans ... the length of the base forms of words in that language. For real-world application of our approach, truncation alsoreduces the table sizes (and thus storage and look-up costs) of any pre-compiled...
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Báo cáo khoa học: Systematic quantification of complex metabolic flux networks using stable isotopes and mass spectrometry pptx

Báo cáo khoa học: Systematic quantification of complex metabolic flux networks using stable isotopes and mass spectrometry pptx

... fractions (M + 0) and (M + 1) of fragment 260 of Ala, fraction (M + 0) of fragment 288 of Val and all the measurements associatedwith fragment 186 of Val. All six measurements areredundant and can be ... of OAA (Asp) ) from TBDMS-Asp fragment 390 – and [2-3] of PYR(Ala) ) from TBDMS-Ala fragment 232 ) based on Eq. (1). Therelationship between the carbon atoms of Glu and these of OAA [2-4] and ... determination of the range of most of the exchange fluxes and the validation of the flux estimatesthrough satisfaction of redundancies. Specifically, we deter-mined that phosphoenolpyruvate carboxykinase and...
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Báo cáo khoa học: Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis potx

Báo cáo khoa học: Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis potx

... Keresztessy2 and La´szlo´Fe´su¨s1,21 Apoptosis and Genomics Research Group of Hungarian Academy of Sciences, Debrecen, Hungary2 Department of Biochemistry and Molecular Biology, Medical and ... of cells [11].The actual enzymatic activity of TG2 is determinedby its structural state induced by the types and amounts of bound ligands [12]. The X-ray structure of TG2 in its GDP-bound and ... results [22], thistype of amino acid replacement does not alter theexpression and stability of mutant proteins. For normalization of protein expression and purity,the binding of a monoclonal antibody...
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Báo cáo khoa học: The identification of a phospholipase B precursor in human neutrophils doc

Báo cáo khoa học: The identification of a phospholipase B precursor in human neutrophils doc

... themajor bands at 22 and 42 kDa, there appeared minorbands at molecular masses of around 20 and 39–41 kDa, which partly shifted from the major bands,coinciding with the appearance of a significant ... 179theoretical isoelectric point and molecular mass of 9.11 and 63 129 Da, respectively, before removal of the pre-dicted signal peptide and 9.01 and 60 147 Da afterremoval of the predicted signal peptide. ... neutrophil origin of PLB precursor. However, the immunoblotting onlyshowed one band at the molecular mass of 42 kDa,whereas no band of the expected size of the entire geneproduct of  60 kDa was...
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