Báo cáo khoa học: Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase Henrik Ingvarsson and Torsten Unge potx
Tài liệu Báo cáo khóa học: Trichostatin A reduces hormone-induced transcription of the MMTV promoter and has pleiotropic effects on its chromatin structure pptx
... methylation [8], and the cleavage of DNA by alkali [31]. The method allows easy detection of DNA–protein interactions via the N7 position of guanines in the major groove and via the N3 position of adenines ... results, and the results of others, highlight the pleiotropic effects that TSA administration has on chromatin structure and on gene expression. Materi...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond pptx
... coiled- coil or other interchain helical structure. Extension of the binding studies to the other LCs showed that LC8-induced DIC dimerization enhances the binding affinity of the dimeric DYNLT and the resulting complex ... DIC dimerization and the binding of light chains and other components of the motor complex including the heavy chain and p150 Glued subunit...
Ngày tải lên: 14/03/2014, 22:20
Báo cáo khoa học: Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases pot
... in the presence of increasing concentrations of both K-49 and RDS1643, and was analyzed using the Yonetani–Theorell plot (Fig. 2). The results show that both slope and intercepts of the plots of ... both RNA and DNA dependent; and (b) RNase H activity that selectively hydrolyzes the RNA strand of the RNA:DNA hybrid formed during synthesis of the minus (–) s...
Ngày tải lên: 22/03/2014, 16:20
Báo cáo khoa học: SAF-3, a novel splice variant of the SAF-1/MAZ/Pur-1 family, is expressed during inflammation pptx
... affect the rate of transcription [33], and ever since the clear demonstration of a causal relationship between hypermethylation of the promoter of tumor suppressor genes and the development of cancer, ... in the unique N-terminus, (b) binding of the N-terminus by ancillary factors, (c) the lack of a negatively functioning module that is present in the N-termi...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: "Linguistically Motivated Features for Enhanced Back-of-the-Book Indexing" ppt
... per- mutation in the book, and then chooses the one with the highest frequency as the correct reconstruction of the entry. In this way, we identify the form of the index entries as appearing in the book, ... segments, and counts the number of segments that include the phrase (within document frequency); the length of the phrase (length of phrase); and...
Ngày tải lên: 08/03/2014, 01:20
Báo cáo khoa học: Glucose oxidase prevents programmed cell death of the silkworm anterior silk gland through hydrogen peroxide production ppt
... the action of 20E and may act to protect the ASGs from early execution of PCD during the feeding stage. GOD was localized in the inner cavity of the gland, and was discharged to the outside of ... with the liquid silk in the silk glands, indicating that trehalase is produced by the silk gland cells and is localized to the cavity of ASGs [19,20]. The silk...
Ngày tải lên: 15/03/2014, 00:20
Báo cáo khoa học: Cell type-specific transgene expression of the prion protein in Xenopus intermediate pituitary cells ppt
... suggesting that the level of GFP–PrP C transgene expression was dependent on the colour of the background of the animal. The fusion protein was found only in the NIL and not in the AL of black- and white-adapted ... examine the effect of the overexpressed Xenopus GFP–PrP C protein on the biosynthesis and processing of POMC as well as the secretion of...
Ngày tải lên: 16/03/2014, 14:20
Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt
... the basis to further investigate the regulation of the cdc2 promoter by LINC in different phases of the cell cycle. Although, so far, only the cdc2 promoter has been analyzed, the promoters of ... serum-starved cells, and that both parts of the CDE-CHR element are required for binding of the complex. These find- ings are consistent with previous studies that reporte...
Ngày tải lên: 23/03/2014, 04:20
Báo cáo khoa học: "a lexicographer''''s workbench supporting state-of-the-art word sense disambiguation" docx
... W1 is the lemma of the word for which Rel holds, W2 is the lemma of the other open-class word involved, Prep is the prepo- sition or particle involved and Pos is the position of W1 in the corpus. ... Lexi- cographers need all the help they can get because the analysis of meaning is the second hardest part of their job (Kilgarriff, 1998), it occupies a large sha...
Ngày tải lên: 24/03/2014, 03:20
Báo cáo khoa học: Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase Henrik Ingvarsson and Torsten Unge potx
... 2010 The Authors Journal compilation ª 2010 FEBS Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase Henrik Ingvarsson and Torsten Unge Department ... amide groups of Ile128 and Arg129. Despite these differences in the coordination of the res- idues in the tip, the fold of the loop is...
Ngày tải lên: 06/03/2014, 22:21