Báo cáo khoa học: BRCA1 16 years later: risk-associated BRCA1 mutations and their functional implications pptx

... BRCA1 mutations and their functional implications R. J. Linger and P. A. Kruk3096 FEBS Journal 277 (2010) 3086–3096 ª 2010 The Authors Journal compilation ª 2010 FEBSMINIREVIEW BRCA1 16 years later: ... accumulation and increased cancerrisk. Using MCF7 breast cancer cells that harbor asingle copy of wild-type BRCA1 and exhibit enhanced Risk-associated BRCA1 mutations and their functional implications ... FEBSMINIREVIEW BRCA1 16 years later: risk-associated BRCA1 mutations and their functional implications Rebecca J. Linger1 and Patricia A. Kruk1,21 Department of Pathology and Cell Biology, University...

Tài liệu Báo cáo khoa học: Identiﬁcation of ATP-NADH kinase isozymes and their contribution to supply of NADP(H) in Saccharomyces cerevisiae docx

... of themutants for UTR1, YEF1 and POS5.Themutants and WT cells were treated and spotted on SD and YPD solid media as des-cribed in Fig. 4A and were grown at 30 °C and 37 °C as indicated.Fig. ... tripolyphosphate and trimetaphosphate at 5 mm and polyphosphate, metaphosphate and hexametaphos-phate at 1 mgÆmL)1) and phosphorylated compounds(phosphocreatine, glucose-6-phosphate and phospho-Table ... other hand, no activitywas detected in the presence of 1 mm Zn2+,Fe2+,Cu2+, and monovalent metal ions (Na+ and Li+).NADPH and NADH slightly inhibited Yef1p; however,NADP and intermediates...

Tài liệu Báo cáo khoa học: "TREATMENT OF LONG DISTANCE DEPENDENCIES IN LFG AND TAG: FUNCTIONAL UNCERTAINTY IN LFG IS A COROLLARY IN TAG" ppt

... char- acterized in Lexical Functional Grammars (LFG) by the use of the formal device of functional un- certainty, as defined by Kaplan and Zaenan [3] and Kaplan and Maxwell [2]. In this paper, ... each node, the t and b statements, with the t statement written above the b statement. Let us say that troo~,broot and tloot= bLoo~ are the t and b statements of the root and foot nodes ... what t and b stand for, it is obvious that on adjoining the statements t, and troot hold for the node corresponding to the root of the auxiliary tree. Similarly, the statements b, and b/oo~...

Báo cáo khoa học: Identiﬁcation of microsomal rat liver carboxylesterases and their activity with retinyl palmitate potx

... between ES4 and hydrolase B (boxed in Table 3) and ES4 and hydrolaseC are underlined in Table 3 and were examined from bothbands and agree with the ES4 sequence. Peak 3 wasidentiﬁed as ES3 and peak ... sequenceES4 band a1 1451.9 1451.9 16/ 26 51–64 LGVPFAKPPL GSLR2 160 0.8 160 1.4 16/ 26 65–78 FAPPQPAEPWSFVK3 976.5 976.5 12/14 97–104 MNDLLTNR4 686.4 686.5 7/8 238–242 NLFHR5 163 0.9 163 1.4 19/30 ... carboxylesterases(ES4, ES10 and ES2) that function as retinyl esterhydrolases in liver. Satoh and Hosokawa [16] proposeda classiﬁcation scheme for carboxylesterases, CES1 and CES2. ES4, ES10 and ES2 belong...

Báo cáo khoa học: Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting pdf

... WS,Martoglio B, Hueber AO et al. (2007) The Fas ligandintracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells. Cell Death Differ 14, 167 8– 168 7.31 Waldhauer I, Goehlsdorf D, Gieseke ... 3-kinase, and Akt. Mol Cell Biol17, 1595 160 6.33 Sympson CJ, Talhouk RS, Alexander CM, Chin JR,Clift SM, Bissell MJ & Werb Z (1994) Targeted expres-sion of stromelysin-1 in mammary gland provides ... 6052–6056.41 Theocharis AD, Skandalis SS, Tzanakakis GN &Karamanos NK (2010) Proteoglycan roles in health and disease: novel proteoglycan roles in malignancy and their pharmacological targeting....

Báo cáo khoa học: "Adaptivity in Question Answering with User Modelling and a Dialogue Interface" pptx

... sentences) and produce the ﬁnal answer accordingly, e.g.:— System: Roald Dahl wrote many books for kids and adults,including: “The Witches”, “Charlie and the Chocolate Fac-tory”, and “James and the ... con-sists of the title and clickable URL of the originat-ing document, and the passage where the sentencewhich best answers the query is located and high-lighted. Question keywords and potentially ... 11, 11 − 16, adult};2) reading level, r ∈ {poor, medium, good};3) webpages of interest/bookmarks, w.Analogies can be found with the SeAn (Ardissonoet al., 2001) and SiteIF (Magnini and Strapparava,2001)...

Báo cáo khoa học: Crystal structure of RNase A tandem enzymes and their interaction with the cytosolic ribonuclease inhibitor potx

... uptake [19]. Tandemizationconsiderably enhances endocytotic internalization intothe cells [20], and potentially impedes binding by RI.Despite their clear cytotoxic action and their dimericstructure, ... of RNase A tandem enzymes U. Arnold et al.340 FEBS Journal 278 (2011) 331–340 ª 2010 The Authors Journal compilation ª 2010 FEBSCrystal structure of RNase A tandem enzymes and their interaction ... III(residues 51–57), a b-strand (residues 61–63) and aloop region (residues 75–79) of the N-terminal entity, and a-helix I¢ (residues 4¢–12¢), a loop region (resi-dues 13¢–18¢) and the end of a-helix...

Báo cáo khoa học: Identiﬁcation of rice TUBBY-like genes and their evolution Qingpo Liu docx

... 7, 8, 11 and 12. By contrast with only oneOsTLP found on chromosomes 3, 4, 7, 8, 11 and 12,three (OsTLP5, OsTLP9 and OsTLP12), two (OsTLP8 and OsTLP13) and three (OsTLP1, OsTLP10 and OsTLP11) ... of chromosomes 11 and 12 and chromosomes 3 and 7, respectively [13,14].With regard to OsTLP8 and OsTLP13, they may havearisen as a result of duplication events, and lost their counterparts ... OsTLP12 and OsTLP5) and part of the long arm of chromo-some 5 (OsTLP11, OsTLP10 and OsTLP1), part ofthe short arm of chromosome 3 (OsTLP14) and partof the long arm of chromosome 7 (OsTLP7), and...

Báo cáo khoa học: Study of uptake of cell penetrating peptides and their cargoes in permeabilized wheat immature embryos pot

... 390,603–612.CPPs and their cargo in wheat A. Chugh and F. Eudes2412 FEBS Journal 275 (2008) 2403–2414 ª 2008 Her Majesty the Queen in Right of Canada, as represented by the Minister of Agriculture and Agri-Food ... for TAT (44-57) into liposomes and intactMDCK cells: novel approach to study membrane per-meation of cell penetrating peptides. Biochim BiophysActa 160 9, 161 169 .33 Fang B, Xu B, Koch P & ... 131–137.A. Chugh and F. Eudes CPPs and their cargo in wheatFEBS Journal 275 (2008) 2403–2414 ª 2008 Her Majesty the Queen in Right of Canada, as represented by the Minister of Agriculture and Agri-Food...

Báo cáo khoa học: "Discriminative Language Modeling with Conditional Random Fields and the Perceptron Algorithm" pptx

... PerceptronAlgorithm, and Conditional RandomFieldsThis section describes a general framework, global linearmodels, and two parameter estimation methods withinthe framework, the perceptron algorithm and a ... methods: the perceptronalgorithm, and a method based on conditional randomﬁelds (CRFs). The models are encoded as determin-istic weighted ﬁnite state automata, and are applied byintersecting ... FieldsConditional Random Fields have been applied to NLPtasks such as parsing (Ratnaparkhi et al., 1994; Johnsonet al., 1999), and tagging or segmentation tasks (Laffertyet al., 2001; Sha and Pereira,...

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