Báo cáo khoa học: BRCA1 16 years later: risk-associated BRCA1 mutations and their functional implications pptx

... BRCA1 mutations and their functional implications R. J. Linger and P. A. Kruk 3096 FEBS Journal 277 (2010) 3086–3096 ª 2010 The Authors Journal compilation ª 2010 FEBS MINIREVIEW BRCA1 16 years later: ... accumulation and increased cancer risk. Using MCF7 breast cancer cells that harbor a single copy of wild-type BRCA1 and exhibit enhanced Risk-associated BRCA1...

Ngày tải lên: 06/03/2014, 22:21

... of the mutants for UTR1, YEF1 and POS5.The mutants and WT cells were treated and spotted on SD and YPD solid media as des- cribed in Fig. 4A and were grown at 30 °C and 37 °C as indicated. Fig. ... tripolyphosphate and trimetaphosphate at 5 mm and polyphosphate, metaphosphate and hexametaphos- phate at 1 mgÆmL )1 ) and phosphorylated compounds (phosphocreatine, glucose-6-p...

Ngày tải lên: 20/02/2014, 01:20

... char- acterized in Lexical Functional Grammars (LFG) by the use of the formal device of functional un- certainty, as defined by Kaplan and Zaenan [3] and Kaplan and Maxwell [2]. In this paper, ... each node, the t and b statements, with the t statement written above the b statement. Let us say that troo~,broot and tloot= bLoo~ are the t and b statements of the root...

Ngày tải lên: 21/02/2014, 20:20

... between ES4 and hydrolase B (boxed in Table 3) and ES4 and hydrolase C are underlined in Table 3 and were examined from both bands and agree with the ES4 sequence. Peak 3 was identified as ES3 and peak ... sequence ES4 band a 1 1451.9 1451.9 16/ 26 51–64 LGVPFAKPP L GSLR 2 160 0.8 160 1.4 16/ 26 65–78 FAPPQPAEPWSFVK 3 976.5 976.5 12/14 97–104 MNDLLTNR 4 686.4 686.5 7/8 238–242...

Ngày tải lên: 08/03/2014, 10:20

... WS, Martoglio B, Hueber AO et al. (2007) The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells. Cell Death Differ 14, 167 8– 168 7. 31 Waldhauer I, Goehlsdorf D, Gieseke ... 3-kinase, and Akt. Mol Cell Biol 17, 1595 160 6. 33 Sympson CJ, Talhouk RS, Alexander CM, Chin JR, Clift SM, Bissell MJ & Werb Z (1994) Targeted expres- sion of stromelysin-1 i...

Ngày tải lên: 15/03/2014, 00:20

... sentences) and produce the final answer accordingly, e.g.: — System: Roald Dahl wrote many books for kids and adults, including: “The Witches”, “Charlie and the Chocolate Fac- tory”, and “James and the ... con- sists of the title and clickable URL of the originat- ing document, and the passage where the sentence which best answers the query is located and high- lighted. Questio...

Ngày tải lên: 17/03/2014, 22:20

... uptake [19]. Tandemization considerably enhances endocytotic internalization into the cells [20], and potentially impedes binding by RI. Despite their clear cytotoxic action and their dimeric structure, ... of RNase A tandem enzymes U. Arnold et al. 340 FEBS Journal 278 (2011) 331–340 ª 2010 The Authors Journal compilation ª 2010 FEBS Crystal structure of RNase A tandem enzymes and...

Ngày tải lên: 22/03/2014, 16:21

... 7, 8, 11 and 12. By contrast with only one OsTLP found on chromosomes 3, 4, 7, 8, 11 and 12, three (OsTLP5, OsTLP9 and OsTLP12), two (OsTLP8 and OsTLP13) and three (OsTLP1, OsTLP10 and OsTLP11) ... of chromosomes 11 and 12 and chromosomes 3 and 7, respectively [13,14]. With regard to OsTLP8 and OsTLP13, they may have arisen as a result of duplication events, and lost th...

Ngày tải lên: 23/03/2014, 07:20

... 390, 603–612. CPPs and their cargo in wheat A. Chugh and F. Eudes 2412 FEBS Journal 275 (2008) 2403–2414 ª 2008 Her Majesty the Queen in Right of Canada, as represented by the Minister of Agriculture and Agri-Food ... for TAT (44-57) into liposomes and intact MDCK cells: novel approach to study membrane per- meation of cell penetrating peptides. Biochim Biophys Acta 160 9, 161 169...

Ngày tải lên: 23/03/2014, 07:20

... Perceptron Algorithm, and Conditional Random Fields This section describes a general framework, global linear models, and two parameter estimation methods within the framework, the perceptron algorithm and a ... methods: the perceptron algorithm, and a method based on conditional random fields (CRFs). The models are encoded as determin- istic weighted finite state automata, and are ap...

Ngày tải lên: 23/03/2014, 19:20