... using the 12 translation libration screwgroups (1 22, 23–65, 66–84, 85–98, 99 11 4, 11 5 13 1, 13 2– 16 4, 16 5 18 8, 18 9–208, 209–2 21, 222–249, 250–294) pro-posed by the program tlsmd [27]. The CysM structure ... positions 94, 11 6, 13 2, 202 and 215 form the lips of the mouth of the active center pocket(Fig. 1) and are therefore important for catalysis. The other peaks correspond to loops at the surface ... 69, 94 and helix a4 (11 8 13 2), and the other is formed byloops 202 and 215 (Fig. 4). The lip positions varygreatly between the structures. Similar changes havebeen reported for the other isozyme,...