Tài liệu Báo cáo khoa học: "The Incremental Generation of Passive Sentences" pot

... sketches some basic features of the SYNPHONICS account of the computational modelling of incremental language production with the example of the generation of passive sentences. The SYNPHONICS ... Incremental Language Production of This paper sketches some basic features of the SYNPHONICS account of the computational modelling of incremental language producti...

Ngày tải lên: 22/02/2014, 10:20

... Moreover, orientation of the CDE ⁄ CHR in the general context of a promoter appears to be rele- vant because inversion of the site in the human Cdc25C promoter resulted in a deregulation of cell cycle-dependent ... determine a role of NF-Y in their control, a number of such genes were implicated to be regulated through CCAAT-boxes. Cotransfection of dominant-negative NF-YA demon...

Ngày tải lên: 16/02/2014, 09:20

... indicate that poly- merization of Gag occurs mainly through the forma- tion of an intermediate layer of cup-shaped structures, each made of one hollow hexameric ring of CA domains placed immediately ... of the precise residues and interac- tions involved in the NTD–CTD interface [46]. Most of these involve side chains from helix 8 of the CTD which pack against the N-terminal e...

Ngày tải lên: 18/02/2014, 06:20

... ring of CAP-1 inserts; the urea and dimethyla- monium groups of CAP-1 also make contacts with the side chains and ⁄ or backbones of several residues in the protein. Thus, most of the contacts of ... shifts of the whole dimer- ization helix of CTD [27] (otherwise, those chemical shifts are too broad to be observed because of the presence of interconverting conformers) [29]. T...

Ngày tải lên: 18/02/2014, 06:20

... biological function of the pro-form of bone morphogenetic protein-2 (BMP-2), a member of the transforming growth factor b (TGFb) ⁄ BLP superfamily. The role of the 263 amino acids of the pro-peptide ... experi- ments demonstrate binding of proBMP-2 to the ECD of BMPR-IA. Interaction of BMP-2 (A) and proBMP-2 (B) with immobilized ECD of BMPR-IA. Interaction of BMP-2 (C) and...

Ngày tải lên: 18/02/2014, 06:20

... structure of hACMSD in complex with DHAP may used for the design of potent and highly selective enzyme inhibitors that may prove to be of potential interest to reduce life-threatening complications of cerebral ... struc- ture-based rational design of enzyme inhibitors with potential medical interest. Results and Discussion Overall quality of the model The three-dimensional structu...

Ngày tải lên: 18/02/2014, 06:20

... 100 lm of (GlcNAc) 1–4 was analysed at the start, in the middle and at the end of each series of sam- ples. The resulting average values of the standards (display- ing standard deviations of < ... 4MU-(GlcNAc) 2 as substrate; 50 lL of supernatant was mixed with 50 lLof 50 mm citrate–phosphate buffer, pH 3.8, containing 50 lm of substrate and 0.1 mgÆmL )1 of bovine serum alb...

Ngày tải lên: 18/02/2014, 08:20

... presence of SDS, and of random coil values for a protein of the same sequence. Fig. S2. In-cell NMR. 1 H- 15 N HSQC spectra of the E. coli slurry [(A), not induced; (B), induced and of the supernatant ... spectra of J1_ic (7.0 lm) in buffer alone and in the presence of SDS (3 mm) at pH 7.4 and at pH 6. Fig. S8. CD of J1_ic. Far-UV CD spectra of J1_ic (7.0 lm) in buffer alone...

Ngày tải lên: 18/02/2014, 16:20

... understanding of the physical interactions underlying the structure, folding and the function of a protein requires a detailed description of its conformational stability in terms of the free energy of ... and values of the thermodynamic parameters governing the heat- and cold-denaturation processes have been obtained. Cold- denaturation of the protein is the result of the com...

Ngày tải lên: 19/02/2014, 12:20

... recognition of p NPP by the pNPP site at t he rear su rface of the N -domain is due the formation of an hydrogen bond of the NO 2 -group of pNPP with the amino group of N398. The hydrophobicity of the ... Characterization of 2¢,3¢-O-(2,4,6-trinitrocyclo hexad ieneylid ine) adenosine 5¢-triphos- phate as a fluorescent probe of the ATP site of sodium and potassium aden osine...

Ngày tải lên: 19/02/2014, 16:20