Tài liệu Báo cáo Y học: The Fc receptor c-chain is necessary and sufficient to initiate signalling through glycoprotein VI in transfected cells by the snake C-type lectin, convulxin ppt

... arginine and cytoplasmic domain of GPVI are necessary for association with the FcR c-chain. Moreover, the FcR c-chain is necessary and sufficient to initiate the signalling events after GPVI engagement, ... of GPVI and the signalling pathways. Many FcRs and their associated b and c-chains bind to each other through the transmembrane domain resulting...

Ngày tải lên: 22/02/2014, 07:20

... se- lected and misleading candidates are discarded. 2.3 Phrasal Translation Query translation ambiguity can be drastically mit- igated by considering the query as a phrase and re- stricting the single ... Bilingual terminology acquisition from target language to source language to yield a second translation model, represented by similarity vectors SIM T →S . - Merge the first...

Ngày tải lên: 20/02/2014, 16:20

... the only analogue that inhibits EII Glc by binding to the high- affinity cytoplasmic binding site and also strongly inhibits sugar uptake mediated by this transporter. The most potent inhibitor in vitro,methyl6,7-anhydro- D , L -glycero-a- D - gluco-heptopyranoside ... EII Glc , rather than binding of Glc, enhanced the reactivity of Cys421. As Cys421 is the only invariant...

Ngày tải lên: 21/02/2014, 01:21

... made by introducing an NsiI site at the translation start point of galA and by then cloning a fragment, starting at this NsiI site and containing the galA gene and approximately 700 bp 3¢-flanking ... degradation of both linear and L -arabinose-substituted galactan side chains of pectin. This is in agreement with a previous study in which the synergy of enzymes degradin...

Ngày tải lên: 21/02/2014, 01:21

... equivalent to the Oe1andNe2ofthe missing Gln30. Interestingly, replacement of this residue by Glu had little effect but replacement by Lys yielded an enzyme too unstable to purify [30]. In E. coli, ... spectrophoto- metrically by its inhibitory action on the superoxide- dependent reduction of cytochrome c by xanthine-xanthine oxidase as described by McCord and Fridovich...

Ngày tải lên: 21/02/2014, 01:21

... currently investigating this possibility. Alternatively, this enzyme may be involved in the epimerization reaction necessary for the biosynthesis of the capsular heptopyranose as alditol acetate ... deviation is due to flexibility, mainly about the glycosidic bonds. Only for residue D having the D -glycero- L -gluco-heptopyranose absolute configuration are short inter-residue...

Ngày tải lên: 21/02/2014, 01:21

... as reported previously [20]. The serine, threonine and tyrosine contents of the hydrolysates were corrected for destruction during the hydrolysis by extrapolation to zero time hydro- lysis. The amino acid ... content in glycine and alanine residues. It is thought to be largely intercrystalline [42] and to provide a framework where mineralization occurs. The soluble...

Ngày tải lên: 21/02/2014, 01:21

... appearance of the ThDP adduct with the substrate moiety during the complex-catalyzed succinyl-CoA hydro- lysis [72] accounts for the inactivation by dihydrolipoamide in the presence of succinyl-CoA ... contribute to the mitochondrial metabolism significantly: NADH is a strong inhibitor of E3 and should thus be much more efficiently oxidized by the enzymes of the resp...

Ngày tải lên: 21/02/2014, 01:21

... deposits begin to appear during the first decades of life and severely impair visual acuity in adulthood. Their therapy is restricted to keratopl- asty and phototherapeutic keratectomy by Excimer ... staining and light microscopy. The results reported in our study are in keeping with these recent clinical reports, as they demonstrate the capacity of forming amyloid fib...

Ngày tải lên: 21/02/2014, 01:21

... efficiency. Also, E. coli RuvA has the ability to bind to the duplex arms of the Holliday junctions after specifically binding to the Holliday junction at the crossover point. From the analysis of the ... analysis of the binding of E. coli RuvA to synthetic Holliday junctions using a variety of biochemical procedures. Specifically we investigated protein–DNA interactions...

Ngày tải lên: 21/02/2014, 01:21