Tài liệu Báo cáo khoa học: "Structural and Topical Dimensions in Multi-Task Patent Translation" ppt

... error rate training In contrast to task pooling and task mixtures, the specific setting addressed by multi-task minimum error rate training is one in which the generative train test pooling mixture A-C ... of tokens and average type frequencies in text sections. We reserved patent data published between 1979 and 2007 for training and documents pub- lished in 2008 for tuning...

Ngày tải lên: 22/02/2014, 03:20

... the input and the first example shown in Figure 4 is calculated using the weights in section 4.2.2 Co), attribute distances as explained in section 4.2.2 (a) and expression (1) at the beginning ... distance metric used when retrieving examples is essential and is explained hem in detail. we suppose that the input and examples (I, E) in the d~tAl~ase ~ r~ted in...

Ngày tải lên: 20/02/2014, 21:20

... HPRT and hypoxanthine. (C) PRTFDC1 and guanine. (D) HPRT and guanine. Table 2. K m and V max values for Hx and G in the presence of 1 mM PRPP, determined using the DE-81 filter paper assay and ... differences in catalytic efficiency could be explained by the difference in amino acid residues involved in catalysis between PRTFDC1 and HPRT. In the structure, residues inter...

Ngày tải lên: 15/02/2014, 01:20

... extents in the FNR–FMN subdo- main interface, including the interface in NOS (Fig. 8). Point mutations that neutralize charge pairing or intro- duce charge-repelling interactions may increase ... The kinetics of interflavin electron transfer (FAD and FMN) in dual-flavin enzymes has been studied using a T-jump method [79] and by observing rates of flavin semiquinone formation (FADH • a...

Ngày tải lên: 18/02/2014, 11:20

... years, we have investigated H-transfer reactions in a number of enzymes, primarily quinoprotein [4,13,14] and flavo- protein [8,15–20] systems. Using a combination of experimental and computational ... bond in synthetic p-p complexes with an accompanying shift to red wavelengths and increase in absorbance. We have recently shown that increasing pressure also causes a shortening of...

Ngày tải lên: 18/02/2014, 11:20

... & Medina M (2004) Role of neighboring FMN side chains in the modulation of flavin reduction potentials and in the energetics of the FMN:apoprotein interaction in Anabaena flavodoxin. Biochemistry ... & Medina M (2008). Flavin role in protein-protein inter- action and electron transfer: from photosystem I to NADPH, a case study. Paper presented at the Flavins and Flavoprote...

Ngày tải lên: 18/02/2014, 11:20

... dimer; and (b) a b-hairpin, which is involved in intersubunit interactions, leading to a loose tetrameric organization of subunits (Fig. 2). The overall structure and the St SurE N-terminal domain ... 242–245, bringing the polypeptide chain back to the same subunit. We analyzed the interactions of corresponding residues in SurEs to understand the reasons for domain swapping. A few str...

Ngày tải lên: 18/02/2014, 14:20

... main-chain and medium side-chain restraints. Model building was carried out in o [29] and coot [30]. In chain A, residues 1 and 169–176 are missing; in chain B, residues 167–172 are missing; in ... chain C, residues 1, 2 and 169–174are missing; in chain D, residues 168–174 are missing; in chain F, residues 1 and 168–175 are missing. All amino acid residues were present...

Ngày tải lên: 18/02/2014, 16:20

... fiber binding or fiber release was coupled to changes in the hypervariable loop. Binding assays Owing to difficulties in expressing and purifying the full-length fiber protein, a 75 amino acid ‘minifiber’ construct ... base binding to integrin. The process by which integrin binding may be coupled to structural changes in the penton base, allowing fiber release, is not clear, but could invol...

Ngày tải lên: 19/02/2014, 06:20

... 720 and 988 ⁄ 989, resulting in two alternative proteins; one short variant encom- passing almost only the CUB domain, and the longer variant containing the CUB domain and the final 30 residues in ... present in mouse heart, liver and kidney [26]. Interestingly, deletion of exon 6 cau- ses a frame shift and an early stop codon in exon 7, resulting in a protein lacking the g...

Ngày tải lên: 19/02/2014, 07:20