Tài liệu Báo cáo khoa học: "An ISU Dialogue System Exhibiting Reinforcement Learning of Dialogue Policies: Generic Slot-filling in the TALK In-car System" pot

... An ISU Dialogue System Exhibiting Reinforcement Learning of Dialogue Policies: Generic Slot-filling in the TALK In- car System Oliver Lemon, Kallirroi Georgila, and James Henderson School of Informatics University ... describe the domain in which the di- alogue system operates (an in- car” information sys- tem). Then we describe the major components...

Ngày tải lên: 22/02/2014, 02:20

... computed in a tractable amount of time, since according to the Markov as- 2 Often these are more complicated than picking informative features as proposed in this paper. One example of the kind of operator ... significant barrier to applying machine learning to new real world domains is the cost of obtaining the necessary training data. To address this prob- lem, work ove...

Ngày tải lên: 20/02/2014, 09:20

... S2. Immunostaining of zebrafish retinal section using antibodies for GS and RPE65c. Fig. S3. Hypothesized molecular mechanisms of the in vitro assay system and the intra-retinal visual cycle. This ... retinoid-binding pro- teins between photoreceptors and retinal pigment epi- thelium (RPE); it is essential for maintaining normal vision [3,4]. The key step in the retinoid visu...

Ngày tải lên: 14/02/2014, 14:20

... proteolytic component of the toxin, and cleaves six members of the mitogen-activated protein kinase kinase family after being delivered to the cytosol by the cell- binding component of the toxin, protective ... antigen. The effect of cleaving these mitogen-activated protein kinase kinases is to interfere with extracellu- lar signal-related kinase (ERK), p38 and c-Jun N-ter...

Ngày tải lên: 16/02/2014, 09:20

... proteins bind their cognate DNA-bind- ing site, they generally bind to other DNA-binding cofactors [10–12]. Meis2 is a member of the TALE superfamily of HD proteins, which are characterized by the ... by the interaction of Pbx1 with the Hth domain of Meis2. Target- ing of the Hth domain to DNA suggests that it is not a portable trans- acting repression domain. However, th...

Ngày tải lên: 16/02/2014, 15:20

... steric interference in the DNA-cleaving catalytic domain of DRc DNAzyme. Reducing the RS to 6 bp increased the rate of DNA cleavage, which approached the self-cleaving rate of DRc DNAzyme in the ... shown in Fig. 4C, RNase A was more efficient than RNase H in triggering the DNA-cleaving activity of DRc DNAzyme. Under the conditions of the DNA-cleaving regulate...

Ngày tải lên: 16/02/2014, 15:20

... suggesting that this peptide may also affect the development of the wing disks at the prepu- pal stages. It is interesting to note that bombyxin-II also stimulated the growth of the wing disks in the butterfly ... but enhances the growth-promoting effect of 20E [32]. In the present study, BIGFLP stimulated BrdU incorpo- ration into the wing disk in the absence...

Ngày tải lên: 18/02/2014, 13:20

... the densities correspond to the N- and C-terminal helices of the c ring, respectively. The C-terminal helices show a clear handedness, and two of the rings face in the opposite direction in the membrane ... to the other two, forming the same pattern as in the AFM surface representation of Fig. 2A. By comparison with the 3D structure of the I. tartaricus c...

Ngày tải lên: 18/02/2014, 17:20

... (DAPK-1) is a Ca 2+ ⁄ calmodulin-regulated serine ⁄ threonine kinase composed of multiple functional domains, including a kinase domain, a calmodulin-binding domain, eight ankyrin repeats, two P-loop ... ⁄ ERK signaling pathway [3]. Moreover, a germline mutation in the death domain of DAPK-1 has been found to reduce intrinsic oligomerization of the death domain, disrupt the bind...

Ngày tải lên: 18/02/2014, 17:20

... in a wide range of proteins, including other GHs (clans E, F and J) [3] and hemo- pexin [20]. The CD spectrum of the latter protein [21] is very similar to the one observed here; therefore, the unusual ... between the catalytic domain and the carbohydrate-binding module. Regions 725–739 and 764–782 of the Cel74A linker were not identified in the chymotryptic map and,...

Ngày tải lên: 19/02/2014, 05:20