... thatthousands of human genes are microRNA targets. Cell120, 15–20.11 Sato F (2011) Epigenetics and miRNA. FEBS J 278,1598–1609.12 Olson EN (2006) Gene regulatory networks in theevolution and development ... important contributor to the development of cardiac dysfunction in diverse patho-logical conditions, such as MI, ischemic, dilated and hypertrophic cardiomyopathies, and heart failure and can be defined ... systems, including cardiovascular development, cardiac fibrosis and arrhythmia [13–15]. As is common to all new and rapidly moving fields, it is relativelyhard to obtain an overview of the available...