Tài liệu Báo cáo khoa học: "Dialogue and Understanding Development Environment, mapping Business Process Models to Information State Update dialogue systeDialogue and Understanding Development Environment, mapping Business Process Modelsms" pptx

... DUDE: a Dialogue and Understanding Development Environment, mapping Business Process Models to Information State Update dialogue systems Oliver Lemon and Xingkun Liu School of ... a new development environ- ment 1 Information State Update dialogue systems which allows non-expert developers to produce complete spoken dialogue sys- tems based only on a...

Ngày tải lên: 22/02/2014, 02:20

... bigrams and punctuation built into it, and the user can specify whether they wish to apply stemming and/ or stop word removal. Like the segmenters, if the user wants to use a specific fea- ture to ... panel allows the user to decide which features the user wants to use in training the model. It is built on top of TagHel- per Tools (Donmez et al., 2005) and uses it to e...

Ngày tải lên: 20/02/2014, 09:20

... to be false to your purposes." The new maxim shifts emphasis from an absolute standard of truth in dialogue to the more pragmatic idea of truth relative to a dialogue& apos;s goals, and ... computational dialogue and ITS. PMMs are intimately connected to ideas of instructional and dialogue focus, the latter of which was explored by Grosz [1977], who stated th...

Ngày tải lên: 20/02/2014, 21:20

... pharmaceutical research and biotechnology. This leads to the question of whether such interest is wisely invested and whether there are success stories to be told for basic science and/ or technol- ogy/biomedicine. ... muscle Mitochondrial NADH/NAD + shuttling activity and muscle glycogen stores affect primarily the cytosolic redox state. Muscle lactate production is regulated pri...

Ngày tải lên: 14/02/2014, 14:20

... such as SAGA and NuA3, which mainly acety- late histone H3, and NuA4 which acetylates histone H4 on K5, K8 and K12. This cascade of events leads to recruitment of transcription factor II H (TFIIH) ... the elongating Pol II. In addition to yeast SAGA and NuA4, the mammalian HAT HBO1 is also potentially able to be recruited to and to acetylate H4 on K5, K8 and K12, as well...

Ngày tải lên: 14/02/2014, 18:20

... cellular processes, including proliferation, dif- ferentiation, apoptosis and development [2]. The nega- tive regulation of gene expression by miRNAs has been reported to contribute to the fine ... factors that regulate self-renewal and pluri- potency: OCT4, SOX2 and KLF4. Castellano et al. [49] revealed that the expression of estrogen receptor-a (ERa) is autoregulated by miR-18a,...

Ngày tải lên: 14/02/2014, 19:20

... for deepening our understanding of diseases. Materials and methods Typing of miRNAs by positional relationship to mRNA transcripts Information about the localization and strand direction of 939 ... cardiovascular diseases [12] and carcinogenesis [13]. The biogenesis and RNAi functions of miRNA (i.e. how miRNAs are generated and processed into a mature form, and how they regu...

Ngày tải lên: 14/02/2014, 19:20

... that thousands of human genes are microRNA targets. Cell 120, 15–20. 11 Sato F (2011) Epigenetics and miRNA. FEBS J 278, 1598–1609. 12 Olson EN (2006) Gene regulatory networks in the evolution and development ... important contributor to the development of cardiac dysfunction in diverse patho- logical conditions, such as MI, ischemic, dilated and hypertrophic cardiomyopathies, an...

Ngày tải lên: 14/02/2014, 19:20

... lm) and RNase A (1–5 pm). Mes was purified prior to use to remove inhibitory contaminants, as described previously [54]. Fluorescence (F) was measured with 493 and 515 nm as the excitation and ... binding and cleav- age by ribonuclease A and variants at Lys7, Arg10, and Lys66. Biochemistry 37, 12121–12132. 31 Anderson DG, Hammes GG & Walz FG Jr (1968) Binding of phosphate l...

Ngày tải lên: 14/02/2014, 22:20

... presence of ATP and Mg 2+ as an activator and P i as an inhibitor. Figure 5 shows that the enzyme exists and functions as a tetramer irrespectively of the presence of activator or inhibitor. We also ... unable to reverse the increase in K m [9]. cN-II has been described as a homotetramer with the ability to change its oligo- merization state in response to the presence of activa...

Ngày tải lên: 15/02/2014, 01:20