Tài liệu Báo cáo khoa học: "FUTURE PROSPECTS FOR COMPUTATIONAL LINGUISTICS " ppt

... FUTURE PROSPECTS FOR COMPUTATIONAL LINGUISTICS Gary G. Hendrix SRI International Preparation of this paper was supported ... machine-readable form, documents relevant to the solution of particular problems are notoriously difficult to locate. Although computational linguistics has no ready solution to the problems of information ... central problems of computational linguistics come up in the use of any medium of communication. For example, one can easily imagine something like speech acts being performed through the...

Tài liệu Báo cáo khoa học: "Asynchronous Binarization for Synchronous Grammars" pptx

... Transforming the entire for- est to n-ary form is intractable, however, becausethe number of hyperedges would be exponential inn. Instead, we include only the top k n-ary back-traces for each forest ... Collapsing BinarizationTo facilitate a change in binarization, we transformthe translation forest into n-ary form. In the n-aryforest, each hyperedge corresponds to an originalgrammar rule, and ... CnnThese rules are also anchored to forest nodes. AnyCiremains anchored to the same node as it was inthe n-ary forest. For the new symbol B, we intro-duce a new forest node B that does not correspondto...

Tài liệu Báo cáo khoa học: A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics ppt

... malignant transformation.Lectin microarray – a powerfultechnology for selection of lectins for cancer glyco-biomarkersThe lectin microarray system is an emerging technique for analyzing glycan ... microarray system is the best tool for a ‘cell proﬁler’, and it is expected to be applicable for selection of cancer-speciﬁc lectins and for qualitycontrol of stem cells before transplantation [12–15].Recently, ... glycosylation and glycansynthesis and the development of bioinformatic tools for their study have been made publicly available asthe Japan Consortium for Glycobiology and Glyco-technology Database (JCGGDB:...

Tài liệu Báo cáo khoa học: S100–annexin complexes – structural insights pptx

... andCa2+-annexin A1 (1MCX) (B) [24]. The core domain repeats are coloured red for repeat I, blue for repeat II, yellow for repeat III and green for repeat IV. The helices of repeat III are labelled A–E. The ... the helix dipole of the annexinN-terminus, and therefore the required helical confor-mation of the peptide. The rmsd for the backbones for the entire Ca2+-S100A11–annexin A1 and S100A10–annexin ... Implications for structure, membrane bind-ing and ion channel formation of the annexin family ofproteins. J Mol Biol 223, 683–704.64 McClintock KA & Shaw GS (2000) A logical sequencesearch for...

Tài liệu Báo cáo khoa học: Structural bases for recognition of Anp32⁄LANP proteins doc

... London) for providing the Lanp clone,which was produced from a cDNA originally providedby Dr A. Matilla (ICH, London), Filippo Prischi for help with the gromacs software, and Dr L Masino for helpful ... into the grooveformed by the concave surface of the LRR domain.Stabilizing interactions could form between His230 ofPP2A-C and Asp119 and Asn94 of Anp32a. A saltbridge could form between Glu226 ... Mountain View, CA,USA) for a total of approximately 5 million clones, wefound about 600 potential positives [i.e. hits that werepositive both for quadruple-dropout media and for 5-bromo-4-chloroindol-3-yl...

Tài liệu Báo cáo khoa học: Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo⁄maltodextrin-binding protein ppt

... cleft formed by the twodomains. A common functional conformational change has been reportedin this protein family, which involves switching from an open formto a sugar-transporter bindable form, ... [11,15]. A common drasticconformational change is found in this protein family,which participates in switching from an open form toa closed form [16]. In EcoMBP, the closed form hasbeen observed ... deﬁned in terms not of the afﬁnities for sugars but of whether the protein adopts the openform or the closed form. TvuCMBP–c-CD complex isseen as the closed form (Fig. 2A,B), and this struc-ture...

Tài liệu Báo cáo khoa học: Temperature compensation through systems biology pptx

... subsequent work.Results and DiscussionGlobal condition for temperature-compensatedﬂuxHere we derive the condition for temperature compensa-tion for a global reaction kinetic network. We refer tothis ... different activation enthalpy combinations. For the sake of simplicity, Eiare activation enthalpies for reaction step i with rate constant ki. For details see supplementary Doc. S1. (1) E1¼ ... Michaelis–Menten constant (Fig. 1).m, used as an index for enzyme-catalyzed processes or todescribe the cooperativity (Hill coefﬁcient) in negative feed-forward ⁄ feedback loops acting from intermediate...

Tài liệu Báo cáo khoa học: Strategies to cover microbial proteomes ppt

... store,manipulate and communicate information has transformed theway we work. In particular, the opportunities and pitfalls for sci-ence opened up by information technology are profound.Nowhere ... their pitfalls and howscientiﬁc progress leads to new challenges for bioinformatics andthe development of resources for biological information that mytalk will concentrate.S4.2-3Nanobiotechnology ... platform. The approach is based onthe neoglycolipid technology that we introduced in 1985 toaddress the need for a microscale technology to present oligosac-charides in a clustered form for...

Tài liệu Báo cáo khoa học: Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase pdf

... product P40 of MPN142,formerly called ORF6 gene. Combining mass spectrometry with a method for sulfonating speciﬁcally the free amino terminal group of proteins, thecleavage site for a typical signal ... SPase typical for Gram-positive bacteria or for Gram-negative bacteria(such as LepB) has been identiﬁed in M. pneumoniae,although a SPase I activity has been shown to beessential for cell viability ... Biosystems).AcknowledgementsWe thank E. Pirkl and M. Ellis for skillful technicalassistance, C U. Zimmerman for critically reading themanuscript, M. T. Saleh for providing the latest resultsof a signal...

Tài liệu Báo cáo khoa học: "A Framework for Syntactic Translation" docx

... S1, which contains all of the information that is in the input sentence. The part of the information that is implicit in the sentence (tense, voice, and so forth) is made explicit in S1. ... certain German verb form into English, it is necessary to un- derstand the German verb form as part of a complex of features of German structure in- cluding possibly other verb forms within the ... provided so that each verb form is understood correctly as a part of that English complex. The form of an English pronoun depends on its English antecedent, while the form of a Ger- man pronoun...

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