Tài liệu Báo cáo khoa học: "The Role Of Focussing in Interpr

Tài liệu Báo cáo khoa học: The role in the substrate speciﬁcity and catalysis of residues forming the substrate aglycone-binding site of a b-glycosidase docx

... was included to facilitate the visualization of the active site. (C) Agly- cone-binding site of SbDhr1, including the substrate dhurrin. (D) Aglycone-binding site of BglB, including the inhibitor ... contribution of each resi- due in the aglycone-binding site to the binding of diverse types of aglycones. Furthermore, these data may be of particular importance in understandin...

Ngày tải lên : 18/02/2014, 17:20

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Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx

... strong, neutralizing action of the cytosolic RNase inhibitor (cRI), a 50-kDa protein containing 16 leu- cine-rich repeat motifs [7,8]. In fact, onconase from Rana pipiens eggs [9], and seminal RNase ... of EIE were recorded at 30° inter- vals of r from 0 to 360°; (d) the inclination of the dimer major axis with respect to the z axis, hence to the membrane plane, was changed (by incl...

Ngày tải lên : 19/02/2014, 06:20

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Tài liệu Báo cáo khoa học: The role of antioxidants in the cytotoxicity of chemotherapeutic drugs pptx

... Quercetin did not inhibit ROS generation, and enhanced cytotoxicity of Topotecan in both cells. In contrast, NAC enhanced resistance against doxorubicine and vincristine in MRP1 overexpressing cells. ... perplexing diversity of lesions is continuously induced in our genes ranging from sin- gle and double strand breaks, to chemical alterations of nucleo- tides including adducts,...

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx

... that the N-terminal domain is involved in protein–protein interactions with other hydrophilic domains of neighboring integral membrane subunits, and interspecies interactions are incompatible. From ... the bovine complex a large subdomain is made up of  20 integral membrane proteins contributing > 60 transmem- brane segments. Some of these must be intimately involved in proton p...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafﬁcking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efﬁcient GABA-uptake activity of the GABA transporter pptx

... evidence that N-glycans, in particular their terminal structures, are involved in regulating the GABA translocation of GAT1, but not in binding of GAT1 to GABA. Transport of GABA by GAT1 across ... that N-linked oligosaccharide side-chains are important for the GABA transport activity. 1-Deoxymannojirimycin inhibits the GABA-uptake of GAT1 In order to gain further insight into...

Ngày tải lên : 19/02/2014, 17:20

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Tài liệu Báo cáo khoa học: The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins pdf

... (sea- urchin sperm protein, enterokinase and agrin) –module cleavage, association of fragments and membrane tar- geting of rat intestinal mucin Muc3. Biochem J 372, 263–270. 12 Maeda T, Inoue M, ... according to the intensity of M2-reactive species in the corresponding whole cell lysate. Molecular modeling of SEA domain of MUC1 The composer and biopolymer modules of the sybyl 6....

Ngày tải lên : 19/02/2014, 18:20

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Tài liệu Báo cáo khoa học: "The Role Of Focussing in Interpretation of Pronouns " pdf

... The Role Of Focussing in Interpretation of Pronouns Candace L. Sidner Artificial Intelligence Laboratory Massachusetts Institute of Technology Cambridge, MA ... anaphora. 2. Focussing provides a control for the inferencing necessary for some kinds of anaphora. The rules confirming restrictions The use of D3 below. D3-I 2 for pronominal anaphora ... pron...

Ngày tải lên : 21/02/2014, 20:20

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Tài liệu Báo cáo khoa học: "The Role of Initiative in Tutorial Dialogue" pdf

... Rules for Assigning Initiative about the effectiveness of Socratic tutoring in the BEE domain or Socratic tutoring in general. 3.2 Initiative Annotation Method The two definitions of initiative we ... an- notated using changes in initiative as a starting point; these changes were taken as marking either a segment endpoint or the beginning of a nested segment. tion following a ques...

Ngày tải lên : 22/02/2014, 02:20

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Tài liệu Báo cáo khoa học: The bacterium, nontypeable Haemophilus inﬂuenzae, enhances host antiviral response by inducing Toll-like receptor 7 expression ppt

... observations bring new insights to our understanding of the interaction between bacteria and viruses in mixed infections. Another major interesting ﬁnding of this study is that NTHi-induced TLR2-dependent ... for mediating NTHi-induced gene transcription, we ﬁrst investigated the role of TLR2 in NTHi-induced TLR7 up-regulation. As shown in Fig. 2A, overexpressing a dominant-nega...

Ngày tải lên : 19/02/2014, 00:20

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Tài liệu Báo cáo khoa học: ˚ The 1.8 A crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species docx

... differences in the fold of the main chains. None of these includes any of the binding sites, but some are located in the vicinity. Three of the regions with different conformation involve calcium binding ... Structures of PRK with inhibitors or sub- Fig. 7. Stereo plot illustrating inhibitor binding in subtilases. The binding loop of chymotrypsin inhibitor II (CI2) in comp...

Ngày tải lên : 19/02/2014, 07:20

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