Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx
Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase pdf
... a density of 6.0 · 10 5 per 100 mm dish for 2 days and then assayed for JNK activity. JNK assays were performed by using a SAPK ⁄ JNK Assay kit (Cell Signaling Technology) according to the manufac- turer’s ... Kit-8 is a colorimetric method in which the intensity of the dye is proportional to the number of the viable cells. Brie y, 200 lL of a suspension of PC-9 ce...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx
... The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex Birgitta Tomkinson, Bairbre Nı ´ Laoi and Kimberly Wellington Department ... ascribed to the insert between Asp and His of the catalytic domain of TPP II. We can now report that the region surrounding Arg252 is of impo...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: The glucose-specific carrier of the Escherichia coli phosphotransferase system Synthesis of selective inhibitors and inactivation studies pptx
... model for the IICB Glc dimer of EII Glc . IICB Glc con- sists of a membrane-spanning C domain (grey) and the cytoplasmic IIB domain (black). IICB Glc is phosphorylated at Cys421 by the sol- uble IIA Glc subunit. ... were recently introduced for the preparation of C-6 aldehyde derivatives of Glc [15]. The key step is the use of Collins reagent for the sele...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... Expression of lacA is also detected in the presence of these compounds, but in the presence of D -xylose and xylan as well. This can be explained by the structure of the polysaccharides. Xylan contains ... galacto-oligosaccharides. ACKNOWLEDGEMENTS The authors thank Simon Flitter for the identification and isolation of the galA containing phage clones and Matthew Il...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Thermostability of manganese- and iron-superoxide dismutases from Escherichia coli is determined by the characteristic position of a glutamine residue pdf
... apoenzymes of each type of SOD may be reconstituted by the addition of metals, the resulting enzyme is active only with the authentic metal at its active centre [4–7]. A small number of cambialistic ... on enzyme activity Hydrogen peroxide, the product of the SOD reaction, is an inhibitor of SODs and an inactivator of FeSOD. It is often used to distinguish be...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168 pdf
... polysaccharide [43]. The role of Cj1428c in Campylobacter polysaccharide biosynthesis is currently unknown. There is no evidence for the presence of fucose in any carbohydrate structures of NCTC ... we are currently investigating this possibility. Alternatively, this enzyme may be involved in the epimerization reaction necessary for the biosynthesis of the capsular h...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... as reported previously [20]. The serine, threonine and tyrosine contents of the hydrolysates were corrected for destruction during the hydrolysis by extrapolation to zero time hydro- lysis. The amino acid ... amide III). Most of the absorption of the later band came within the region 1390 ± 40 cm )1 , in which the methyl or methy- lene deformations are also active....
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species pptx
... the thiyl radical of the lipoyl residue should efficiently interact with the E1 catalytic intermediate, as the lipoyl-bearing domain of E2 is designed for this interaction (reaction 2). In this ... substrate moiety during the complex- catalyzed succinyl-CoA hydro- lysis [72] accounts for the inactivation by dihydrolipoamide in the presence of succinyl-CoA (Table...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx
... putative therapeutic agents for these disabling diseases. Keywords: amyloidosis; keratoepithelin; lattice corneal dys- trophy; granular corneal dystrophy; synthetic peptide. Hereditary corneal dystrophies ... and severely impair visual acuity in adulthood. Their therapy is restricted to keratopl- asty and phototherapeutic keratectomy by Excimer laser. Unfortunately, the benefits of the...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: The RuvABC resolvasome Quantitative analysis of RuvA and RuvC assembly on junction DNA doc
... analysis of the RuvAC–Holliday junction ternary complex To further examine the hypothesis that a tetramer of RuvA can bind to each face of a Holliday junction, the effect of the addition of RuvC ... R max RuvA is the maximum response of RuvA binding, R junc is the response of the binding of the biotinylated Holliday junction, M r RuvA is the molecular...
Ngày tải lên: 21/02/2014, 01:21