Tài liệu Báo cáo khoa học: Isoprenoid biosynthesis via the methylerythritol phosphate pathway Mechanistic investigations of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase ppt

... 4457 Isoprenoid biosynthesis via the methylerythritol phosphate pathway Mechanistic investigations of the 1-deoxy- D -xylulose 5 -phosphate reductoisomerase Jean-Franc¸ois Hoeffler, Denis Tritsch, Catherine ... this hypothesis, the influence of the concentrations of NADP + and MEP 5 ,the substrates of the reverse reaction, and of NADPH and DXP 3, the pr...

Ngày tải lên: 21/02/2014, 03:20

... several molecular pathways. The best characterized and the most prominent path- ways are the extrinsic and intrinsic pathways. In the intrinsic pathway (also known as the ‘mitochondrial pathway ), apoptosis ... decreasing the activity of caspase-3 in the three cell lines. Effect of HSS knockdown on CCCP-induced apoptosis To further elucidate the functional role of HSS...

Ngày tải lên: 16/02/2014, 09:20

... in the central cylinder of the root, but not in the lower parts of the hypocotyl (a). Rosette leaves were stained in the vascular tissue of the leaf blade, whereas the petiole and older parts of ... staining within the vascular tissue at the end of the leaf blade, whereas the basal parts close to the petiole remained almost unstained. We observed clear GUS ex...

Ngày tải lên: 18/02/2014, 06:20

... 1. The 18 kDa protein present in the elution pattern was identified as the PHI component on the basis of its ability to complement the Fig. 1. SDS/PAGE of PHI at different steps of purification. The numbers ... equilibrium. As shown in the inset, the progressive decrease of the molecular ellipticity at k ¼ 200 nm (the absorption region of the peptide bond) reflects...

Ngày tải lên: 21/02/2014, 00:20

... signaling pathways, such as the ERK1 ⁄ 2 pathway and the Akt pathway, as a conse- quence of inactivation of the EGFR [12]. With refer- ence to Fig. 1, which presents an overview of the intracellular ... inhibi- tion of Akt- and ERK1 ⁄ 2-dependent pathways eventu- ally change the expression level of one or more of these Bcl-2 family members. Bad Bad is one of the ‘...

Ngày tải lên: 16/02/2014, 09:20

... that argued against the existence of the complex and channeling of metabolites [10,11]. Thus, the existence of the com- plex has not been universally accepted. In addition to the cytoplasmic compartment, ... reduced by the coexpression of citrine–GAPDH, but coexpres- sion of PGK did not affect the lifetimes. Coexpression of citrine–GAPDH and PGK weakly decreased the...

Ngày tải lên: 16/02/2014, 09:20

... obesity. Experimental procedures Generation of H-PGDS TG mice The coding region of human H-PGDS was cloned into the downstream sites of the chicken b-actin promoter and the CMV enhancer of the pCAGGS expression vector ... analysis To further assess the effect of H-PGDS overexpression on the increase in adipose tissues, the weights of subcutaneous and visceral adipo...

Ngày tải lên: 16/02/2014, 09:20

... just the result of the larger ionic radius of Cd(II) over Zn(II) and that the difference in amino acid sequence plays a role. One of the most important aspects is the greater dynamics of the Cd(II) 3 -CysS 9 cluster ... in the pro- tein. The modification of the surface-accessible sulfur of cysteine ligands is thought to be the key that unlocks the metals from...

Ngày tải lên: 16/02/2014, 15:20

... describe the function of the entire pathway [13]. This practice allows the investiga- tor to omit inessential complexity and to focus on the elements underlying the emergence of function of the pathway. ... phenomenon is offered by an enzyme-catalyzed reaction where the function is the conversion of one metabolite into another: in this case, the formation and disp...

Ngày tải lên: 18/02/2014, 06:20

... from the Ministry of Education, Culture, Sports, Science and Technology of Japan, a grant from the program ‘Research for the Future’ of the Japan Society for the Promotion of Science, and the ... vessels and their transfer to distant areas in the brain via blood flow; (b) the rapid migration of tumor cells outside blood vessels; and (c) the migration of tumor ce...

Ngày tải lên: 18/02/2014, 11:20