Tài liệu Báo cáo khoa học: Amyloidogenic nature of spider silk ppt
... similarities in the nature of spider silk and amyloidogenic fibril formation. This suggests that spider- silk processing, not the least for the large quantities of material produced in vivo in the spider, ... spinning of spider silk. Nature 410, 541–548. 2. Simmons, A., Michal, C. & Jelinski, L. (1996) Molecular orientation and two-component nature of the crystal...
Ngày tải lên: 21/02/2014, 03:20
... problem of unscrambling English affixes. The role of affixes is crucial in the study of word-breaking practice. In the automatic determination of the parts of speech (a central feature of automatic ... determination of parts -of- speech assignments E. The determination of the number of phonetic syl- lables corresponding to a written English word In the first case, we hav...
Ngày tải lên: 19/02/2014, 19:20
... final out- come of the treatments. In a recent study, the effect of melatonin (25 lgÆmL )1 of drinking water, % 500 lg per day) on a 10-week-long treatment of male rats with a low dose of methylprednisolone ... & Szabo C (1998) Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NF kappa B activation...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Molecular basis of glyphosate resistance – different approaches through protein engineering doc
... however, was devoid of substrate or inhibitor, and consequently did not reveal the nature of the active site or the mode of action of glyphosate. A dec- ade later, the crystal structure of EPSPS was ... molecular mode of action of glypho- sate and the molecular basis for glyphosate resistance. Structure and function of EPSPS EPSPS catalyzes the transfer of the enolpyruvyl...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học:Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau ppt
... of tau with Fyn-SH3. We also show that tau interacts with the SH2 domain of Fyn, and that this associa- tion, unlike that of Fyn-SH3, is influenced by Fyn-mediated tyrosine phos- phorylation of ... SH3 domain of Fyn binds to proline-rich motifs within the sequence PXXP in interacting pro- teins. Seven such motifs are present in the proline-rich domain of the longest isoform of ta...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học: Crystal structure of an ascomycete fungal laccase from Thielavia arenaria – common structural features of asco-laccases ppt
... determined by the nature and position of substituents on the phe- nolic ring of the substrate. Second, the redox potential (E°) of the substrate must be low enough, as the rate of the reaction ... buffer at pH 6.0 (25 °C). Structural formulas of the substrates are presented. Redox potentials (E°)ofT1 coppers of the laccases and redox potentials of the substrates at pH 4.5 and...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt
... reservoir consisted of 500 lL of 0.7 m sodium citrate, 10 mm dithiothreitol and 70 mm Hepes at pH 7.4. Drops consisted of 0.75 l L of importin-a (70-529) at 18 mgÆmL )1 , 0.75 lL of CLIC4 NLS peptide ... Luria–Bertani medium containing 30 lgÆmL )1 of kanamycin. Flasks of 400 mL of Luria– Bertani medium (30 lgÆmL )1 kanamycin) were then inocu- lated with 10 mL of the overnigh...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: PCR detection of nearly any dengue virus strain using a highly sensitive primer ‘cocktail’ ppt
... comparison. Effect of geographical variation in dengue virus on the performance of the primer cocktail Each of the four serotypes of dengue virus can be classi- fied into several genotypes, defined as a group of ... Yuriy Fofanov 1,3 and Richard C. Willson 1,7 1 Department of Biology and Biochemistry, University of Houston, TX, USA 2 Department of Chemical and Biomolecular Engin...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf
... (Fig. 3A). Three of the ligands, OD2 of Asp165, NE2 of His79 and NE2 of His169, formed an equatorial plane. The other protein ligand, NE2 of His31, bound to the metal, in the company of a water oxygen, ... conformation around the active site of ApeSOD is independent of the presence of a metal cofactor. Figure 3D shows the superimposition of the active site structures of...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt
... quantitation of microgram quantities of protein uti- lizing the principle of protein-dye binding. Anal Bio- chem 72, 248–254. 48 Laemmli UK (1970) Cleavage of structural proteins during the assembly of ... report data on homologous expression of the nrdF gene of C. ammoniagenes strain ATCC 6872. This is the first report of the successful purification of high amounts of the n...
Ngày tải lên: 15/02/2014, 01:20