Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf

... terminal in the grammar. If A is a terminal then G A is the distribution that puts all of its mass on the unit tree (i. e., tree consisting of a single node) labeled A. If A is a nonterminal then G A is ... by in effect learning the probability of the subtrees rooted in a specified subset M of the nonterminals known as the adapted nonterminals. Adap...

Ngày tải lên: 20/02/2014, 09:20

... Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I Kentaro Shiraki 1 , Shigemi Norioka 2 , Shaoliang ... interest in the aromatic stacking is in the role of the electrostatic properties in enzymatic catalysis of API, and in distinguishing t...

Ngày tải lên: 21/02/2014, 03:20

... the elas- tase-inhibitory capacity of alpha 1-proteinase inhibitor in vitro. J Clin Invest. 66, 987–995. 24 Bieth JG (1984) In vivo significance of kinetic constants of protein proteinase inhibitors. ... that (a) the observed inhibition is lower than that with the theoretical inhibitor, regardless of the enzyme, the inhibitor and the state of oxidation of the latt...

Ngày tải lên: 19/02/2014, 07:20

... containing helix I when placed on a spatial model (Fig. 3). This cluster is located diametrically to the pole carrying the amino acids involved in substrate binding. As far as we know, there has ... P450 extraction. The arrow points to the CYP 6A2 specific signal, the star indicates unspecific signal observed in all lanes loaded with bacterial protein. The CYP 6A2 variants h...

Ngày tải lên: 19/02/2014, 12:20

... Eugenin was isolated from HPLC traces of animals in the first two weeks of lactation. The fraction containing eugenin is indicated by an asterisk in Fig. 2. Two further HPLC separations of the initial ... 16 Wakabayashi H, Matsumoto H, Hashimoto K, Teragu- chi S, Takase M & Hayasawa H (1999) Inhibition of iron ⁄ ascorbate-induced lipid peroxidation by an N-ter- minal pept...

Ngày tải lên: 19/02/2014, 16:20

... particular importance in our abil- ity to engineer increased protein–protein interaction stability at will; in particular, the ability to increase stability by kinetic design. For example, by achieving this ... permitting a rigid interpretation in distinguish- ing interacting from noninteracting proteins. One Fig. 1. Schematics of library designs. The helical wheel diagram looks...

Ngày tải lên: 18/02/2014, 13:20

... (buthinin), CTMIPIPRC (tigerinin), etc. Also remarkable is the observation that lactoferricin B (a tryptophan/arginine rich antibiotic peptide), when enzymatically cleaved from lactoferrin adopts ... results indicated that residues 23–35 of mussel defensin MGD1 play a key role in the binding to Gram-positive bacteria, inhibiting bacterial growth and permeabilizing bacteria. Moreo...

Ngày tải lên: 20/02/2014, 11:20

... obtained for alanine, threonine, glycine, valine, phenylalanine and aspar- tate. The analysis, starting from protein hydrolysis, was performed in quintuplicate. Activity assays For all activity ... unit that contains the catalytic site, rather than on an auxiliary domain [9]. These substrate bind- ing sites are located at a certain distance from the active site and are called second...

Ngày tải lên: 14/02/2014, 19:20

... diin ra hai diin dan kinh te d Davos (Thuy Si) va xa hoi d Belem (Braxin). O ca hai dien dan nay va'n de chinh la ban ve giai phap giai quyet cudc KH kinh te the gidi. ... My Latinh do cac dang Xa hdi cam quyen nhU Braxin, Achentina, Chile, Uruguay, Paraguay. Cac dang nay dn hda hdn vi cdn nhin thai do ciia cac dang Xa hdi Chau Au dang tim each thoat ra...

Ngày tải lên: 17/02/2014, 05:20

... from stress-induced damage by preventing protein denatur- ation and ⁄ or repairing such damage [1]. Mammalian heat shock proteins are classified into several families on the basis of their apparent ... activator of transcription-3 Nobuyuki Yamagishi, Hajime Fujii, Youhei Saito and Takumi Hatayama Department of Biochemistry & Molecular Biology, Division of Biological Sciences, Kyo...

Ngày tải lên: 18/02/2014, 06:20