Tài liệu Báo cáo khoa học: Fra-1 targets the AP-1 site/2G single nucleotide polymorphism (ETS site) in the MMP-1 promoter docx
Tài liệu Báo cáo khoa học: Cobalamin uptake and reactivation occurs through specific protein interactions in the methionine synthase–methionine synthase reductase complex docx
... footnote) in the reaction
mixture may reduce a proportion of the FMN domain,
converting some of the enzyme to the active form. The
3-fold increase in activity may arise from the binding
of the FMN ... mL.
The reactions were initiated by the addition of homo-
cysteine following 5 min of incubation at 37 °C of the
enzyme with all other components. Following 10 min of
i...
Tài liệu Báo cáo khoa học: Molecular and cellular specificity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx
... present in the
neuroendocrine organ, a puzzling question remains
unanswered: how are these peptides distributed in the
different cells of the X organ–sinus gland system? In
other words, what is the ... the
results obtained in the crayfish Orconectes limosus,
showing that l-isomer of CHH is always present in the
different parts of the d-CHH cells, in decreasing
amoun...
Tài liệu Báo cáo khoa học: Altered inactivation pathway of factor Va by activated protein C in the presence of heparin doc
... the
mechanism in which heparin binding to the basic cluster in
APC is responsible for the observed inhibitory activity. A
direct effect of heparin on APC can also explain the
stimulation of the ... the NMR/modeled structure of
heparin (file 1hpn [35]).
Amino acids known to be part of the heparin-binding site
in these three crystallized protein–heparin complexes were
given a...
Tài liệu Báo cáo khoa học: Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain ppt
... of proteins
involved in retinoid-related metabolism (retinoic acid
receptors, cellular binding proteins and oxidizing enzymes)
have been mapped within the adult dopamine system [35].
In the adult ... data
indicate that adult brain tissue, in particularly the striatum,
can oxidize retinol to retinal, providing the first step on the
way to retinoic acid [31]. The brain must thu...
Tài liệu Báo cáo khoa học: Fra-1 targets the AP-1 site/2G single nucleotide polymorphism (ETS site) in the MMP-1 promoter docx
... con-
sensus binding sites present in the promoter. Another ETS
site in the MMP-1 promoter is created at )1607 bp by a
single nucleotide polymorphism (SNP), which contains two
guanines (5¢-GGAT-3¢; ... reduction in MMP-1 mRNA
occurred at the level of transcription, was greater in the 2G
SNP-containing promoter than in the 1G SNP-containing
promoter, and requ...
Tài liệu Báo cáo khoa học: Chromatin under mechanical stress: from single 30 nm fibers to single nucleosomes pdf
... analysis with load-
ing rates in the range 2.4–11 pNÆs
)1
revealed that the
dependence of the probability of unwrapping on the
force was not linear. Therefore, the unwrapping of the
inner turn cannot ... observed in the case of stretching experiments
using chromatin reconstituted in X. laevis egg extracts
[38].
The part of the stretching profile interpreted as ‘con-
tin...
Tài liệu Báo cáo khoa học: Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay docx
... explanation for the fact that certain in u-
enza strains do not agglutinate cRBCs, using specific human-adapted
in uenza hemagglutinins as examples. Finally, recent understanding of the
role of various ... particles and assays that measure the
binding of a virus particle to a cell, representative of
the first step in the infection cycle. In the former cate-
gory, assays includ...
Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: a capacitative (AC) electrical coupling model in neuroepithelium pptx
... cadherin interacts with
F-actin via b-catenin and a-catenin; b-catenin binds
to cadherin and a-catenin, which in turn interacts with
F-actin (Fig. 3A) [24]. Thus b-catenin plays a pivotal
role in the ... cadherin–catenin complexes within each
cell and by cadherin–cadherin interactions between the
two cells. The interkinetic cells adhere to each other
via cadherin–catenin complexes,...
Tài liệu Báo cáo khoa học: Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters docx
... Dashed
lines indicate van der Waals contacts with interatomic distances in A
˚
. Dotted lines indicate C-HÆÆÆO interactions. Black lines indicate interac-
tions in SQV complexes. Red lines indicate interactions ... shown in A
˚
with black lines indicating PR
WT
and
red lines indicating the mutant. Interatomic distances of > 4.3 A
˚
are shown in dash-dot lines to indicate the ab...