Tài liệu Báo cáo khoa học: Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain ppt

... 2003 Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain Dagmar Galter 1 , Andrea Carmine 1,2 , Silvia Buervenich 1,2 , Gregg Duester 3 and ... significant involvement of ADH1 and ADH4 in ethanol oxidation in brain tissue. Regarding retinoid metabolism in the adult brain, enzymes other th...

Ngày tải lên: 21/02/2014, 00:20

... cadherin interacts with F-actin via b-catenin and a-catenin; b-catenin binds to cadherin and a-catenin, which in turn interacts with F-actin (Fig. 3A) [24]. Thus b-catenin plays a pivotal role in the ... Ca 2+ store or the ONM [4,7]. The store BK channels are activated by a positive voltage change on the luminal side and by an increase in the luminal [Ca 2+ ] [4,7]. Beca...

Ngày tải lên: 16/02/2014, 09:20

... first identified in the epithelial lining of the gut and skin, and subse- quent studies have shown it to play a role in the regu- lation of cellular growth and differentiation in these tissues [1]. ... adhesion to the endothelial surface and prolongation of clotting time following the induc- tion of KLF4 under in ammatory states, and implicat- ing KLF4 as a re...

Ngày tải lên: 18/02/2014, 04:20

... large part of their internal volume for functionalized invaginations of the intracyto- plasmic membrane containing the photosynthetic machinery. The most abundant protein complexes in the intracytoplasmic ... energy- transducing network. Protein packing may play a determining role in the formation of functional photosynthetic domains and membrane curvature. To further in...

Ngày tải lên: 18/02/2014, 18:20

... between the mainly black feather colour of chickens possessing E and E R and the presence of constitutively active MC1 receptor is in line with the previous observation of the E92K mutation in other species. ... lLofthe supernatant after addition of [ 3 H]cAMP and bovine adrenal binding protein and incubation for 2 h at 4 °C. Standards containing nonlabeled cAMP we...

Ngày tải lên: 21/02/2014, 00:20

... nonspe- cific, disruptive effect on the binding of antibodies to antigens such as laminin and myosin (data not shown). Both HB-19 and lactoferrin bind to the C-terminal RGG domain of nucleolin. Therefore, ... out using the protein lactoferrin. Lactoferrin, an iron- binding protein of the transferrin family, is present in external secretions and the secondary granules o...

Ngày tải lên: 19/02/2014, 05:20

... single line scan data obtained with buffer conditions. (A) Representative single line scan graphs obtained at increasing ATP concentration in the range 0–100 l M and in the presence of 10 nM and ... (long-distance move- ment of the N-domain and rotational motion of the A-domain) of SERCA during the ATP-mediated ion transport reaction [14,16–19]. The single line s...

Ngày tải lên: 14/02/2014, 14:20

... mediator of lethal sepsis, triggering the production of proinflammatory cytokines and liver injury [13]. Therefore, the present study aimed to elucidate the role of KCs in the regulation of CYP isoform ... lead- ing to hepatotoxicity in liver injury, including endotox- emia and ischemia ⁄ reperfusion injury [14]. In our studies, we employed GdCl 3 to inactivate KCs ba...

Ngày tải lên: 14/02/2014, 18:20

... fibril building blocks only after partial unfold- ing of the a-helix from the body of the b-sheet (Fig. 2C). Possible role of domain-swapping in the ‘off-pathway folding’ (OFF) model The OFF model ... templating and nucleation; (b) linear, colloid-like assembly of spherical oligomers; and (c) domain-swap- ping. In this review, we stress the role of domain-swapping...

Ngày tải lên: 14/02/2014, 18:20

... 1B shows the pattern seen after the development of the blot. With increase in time of incubation, the intensity of the band for the monomeric protein decreased, whereas the bands for the higher ... line), in the presence of 100 l M neurotoxin ( • , dotted line), in the presence of 200 l M neurotoxin ( , dotted line) and in the presence of neurotoxin...

Ngày tải lên: 14/02/2014, 19:20