Tài liệu Báo cáo khoa học: "RELATING COMPLEXITY TO PRACTICAL PERFORMANCE IN PARSING WITH WIDE-COVERAGE UNIFICATION GRAMMARS" pptx

... RELATING COMPLEXITY TO PRACTICAL PERFORMANCE IN PARSING WITH WIDE-COVERAGE UNIFICATION GRAMMARS John Carroll University of Cambridge, Computer Laboratory Pembroke Street, ... polynomial -complexity bottom-up CF parsing algorithms. Although incorporating unification increases their complexity to exponential on gram- mar size and input length (section 3), this a...

Ngày tải lên: 20/02/2014, 21:20

... a C-terminal extension to the protein kinase folds back on the kinase domain and interferes with the substrate binding sites. In the case of the titin and twitchin kinases, the autoinhibitory sequence ... occurring on binding of the peptide and could indicate that the binding of PhK5 to Ca 2+ ⁄ CaM is similar to that observed for Ca 2+ ⁄ CaM binding to isolated peptides from other...

Ngày tải lên: 19/02/2014, 17:20

... tyrosines present on tau [17–19], and tau also interacts with Fyn via its Src homology (SH)3 domain [20,21]. The SH3 domain of Fyn binds to proline-rich motifs within the sequence PXXP in interacting ... tau contains tyrosines that could be targeted by Fyn, and tyrosine phosphorylation in uences Fyn- SH2 binding to target proteins, we set out to deter- mine whether or not tau binds...

Ngày tải lên: 14/02/2014, 14:20

... expenditure. Thus, insulin, leptin and ghrelin, as well as other hormones ⁄ cytokines, interact with their cognate receptors on neurons within the CNS that project to higher brain centers and to peripheral ... higher organisms, this involves storing energy as fat during periods of an abundant food supply to hedge against periods of food shortage. Today, humans have pushed storage too...

Ngày tải lên: 14/02/2014, 22:20

... role in polygluta- mine-induced disease in SCA1 transgenic mice. Cell 95, 41–53. 6 Saudou F, Finkbeiner S, Devys D & Greenberg ME (1998) Huntingtin acts in the nucleus to induce apopto- sis ... pan-caspase inhibi- tor selectively increased the accumulation of the C-terminal fragment in the cytoplasm, which recapitu- lated the cytoplasmic inclusion seen in the DRPLA brain. Take...

Ngày tải lên: 15/02/2014, 01:20

... proteins (Fig. 6). These proteins are the activating enzyme involved in quinohemopro- tein amine dehydrogenase biosynthesis, which is involved in the cross-linking of cysteinyl residues with glutamate ... the product formed, and kinetic experiments demonstrated that, in both cases (i.e. with a cysteinyl- containing peptide or a seryl-containing peptide) a strict 1 : 1 coupling betwe...

Ngày tải lên: 16/02/2014, 14:20

... inserting PCR prod- uct coding for BOIP (accession number: AAI69777) [20] in fusion with flag epitope into pcDNA3.1()) plasmid. DNA constructs used to express HA-tagged TIAR-interacting proteins ... interactions between cis-acting elements mainly localized in the UTRs of the transcript and the trans-acting factors (RNA-binding proteins and noncoding regulatory RNAs) that bind to thes...

Ngày tải lên: 16/02/2014, 15:20

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Ngày tải lên: 17/02/2014, 05:20

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Ngày tải lên: 18/02/2014, 03:20

... associated with nuclear locali- zation within the developing neural tube [3,62,121]. In addition, mHSF2 is associated with DNA binding in the developing brain, including cortex, striatum, olfactory ... HSF4 on chromatin. In the absence of HSF4, histone H3K9 methylation is induced and HSF1 binding is reduced, indicating that HSF4 facilitates HSF1 binding via chromatin remodelling. He...

Ngày tải lên: 18/02/2014, 04:20