Tài liệu Báo cáo khoa học: "THE EFFEC TO FEST ABLISHING COHERENCE ELLIPSIS AND ANAPHORA RESOLUTION" pdf

... THE EFFECT OF ESTABLISHING COHERENCE IN ELLIPSIS AND ANAPHORA RESOLUTION Andrew Kehler Harvard University Aiken Computation Laboratory 33 Oxford Street Cambridge, ... Fiengo and May (1990) and Lappin (1993) note the unacceptability of examples such as (8) and (9): (8) * I hit Billi, and then hei did too. (9) * Mary introduced Johnj to everyone, and hej did too. ... ,This letter provoked a response from Bush, and Clinton did too. [ responded ] (23) * There is a rise in American visitors to the city, and Canadians do too. [ visit the city ] A similar pattern...

Tài liệu Báo cáo khoa học: The Mycobacterium tuberculosis membrane protein Rv2560 ) biochemical and functional studies pdf

... synthesized and tested for their ability to bind to A549 and U937 cells. Peptide 11024 (121VVALSDRATTAYTNTSGVSS140)showed high speciﬁc binding to both cell types (dissociation constants of380 and 800 ... it to penetrate, survive and grow within these compartments [5]. Adhesion and phagocytosis are the initial steps in the entry of thebacterium into macrophages, processes triggered byreceptor–ligand ... speciﬁc, sensitive and robust receptor–ligandbinding assay was developed, based on previous stud-ies with erythrocytes and hepatocytes [17–19]. Thismethodology was adapted to other cell types,...

Tài liệu Báo cáo khoa học: The two Caenorhabditis elegans metallothioneins (CeMT-1 and CeMT-2) discriminate between essential zinc and toxic cadmium docx

... nmCd(II) and 0.7 lm Zn(II)] and 0.1 lm of CeMT-1 and CeMT-2 each, and the stability constants given inTable 2, it can be calculated that 98.6% of Cd(II) isbound to CeMT-2, and only 1.4% to CeMT-1. ... into predo-minantly CeMT-2 in a common cytosol.DiscussionLike other soil-dwelling organisms, C. elegans nema-todes are constantly exposed to and ingest varying lev-els of essential and toxic ... proﬁles in wild-type nematodes and standards. CdXANES spectra (A) and Zn XANES spectra (B). For cadmium,a minor monochromator drift during data collection made itnecessary to correct the edge position...

Tài liệu Báo cáo khoa học: The nuclear lamina Both a structural framework and a platform for genome organization pdf

... Margalit A, Segura-Totten M, Gruenbaum Y & WilsonKL (2005) Barrier to autointegration factor is required to segregate and enclose chromosomes within thenuclear envelope and assemble the nuclear ... intermedi-ate ﬁlament cytoskeletons: from structure to assembly to gene ablation. Int Rev Cytol 223, 83–175.15 Foster HA, Abeydeera L, Grifﬁn DK & Bridger JM(2005) Non-random chromosome positioning ... lower phylalike cnidaria or nematodes and four major forms inmammals, designated A-type (lamin A and lamin C) and B-type (lamin B1 and lamin B2), in addition to anincreasing number of associated...

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf

... during fetal liver and deﬁnitive hematopoiesis. This enables the activation ofanti-apoptotic pathways and stem cell maintenance[9,10]. Leukemic cells seem to have the ability to inter-act with ... GSK3 inactive and allows physiolo-gical reactions such as b-catenin and insulinsignaling, as well as apoptosis. Active GSK3blocks HH signaling via SMO, and alsoblocks apoptosis and MYC-mediatedactions. ... clonal growth and stabilizes mitochondria. Inhibition ofactive GSK3 by lithium or other GSK3inhibitors leads to cell growth, but mayblock differentiation and cause induction ofapoptosis in MLL-rearranged...

Tài liệu Báo cáo khoa học: "Grammar Error Correction Using Pseudo-Error Sentences and Domain Adaptation" pdf

... CorrectionUsing Pseudo-Error Sentences and Domain AdaptationKenji Imamura, Kuniko Saito, Kugatsu Sadamitsu, and Hitoshi NishikawaNTT Cyber Space Laboratories, NTT Corporation1-1 Hikari-no-oka, ... restricting the error types to articles and frequent prepositions (Gamon, 2010;Han et al., 2010; Rozovskaya and Roth, 2011).On the contrary, Mizumoto et al. (2011) proposedtranslator-based error correction. ... byreferring to a phrase table. This table, called theconfusion set (Rozovskaya and Roth, 2010a) inthe error correction task, stores pairs of incorrect and correct particles (Table 1). The candidates...

Tài liệu Báo cáo khoa học: The tandemly repeated domains of a b-propeller phytase act synergistically to increase catalytic efﬁciency doc

... InsP6can be hydrolyzed com-pletely to produce one inositol and six moleculesof inorganic phosphate, or partially to produce lowerinositol polyphosphate (IPP) isomers and inorganicphosphates [3].Among ... asix-blade b-propeller containing ﬁve four-strandedsheets and one ﬁve-stranded sheet.Expression and puriﬁcation of PhyH, PhyH-DI and PhyH-DIIPhyH, PhyH-DI and PhyH-DII were each expressed inEscherichia ... anempty pET-22b(+). PhyH, PhyH-DI and PhyH-DIIwere puriﬁed to homogeneity by Ni-afﬁnity chroma-tography and were found to have apparent molecularweights of 67.0, 31.0 and 36.0 kDa (Fig. 1A), respec-tively....

Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx

... kinase PTO, which confersresistance to the bacterial pathogen P. syringae pvtomato carrying the avirulence effector proteins AvrPtoor AvrPtoB [17,18].The OXI1 protein kinase was also shown to ... strongsequence identity to the tomato PTI1 kinase. In Ara-bidopsis, 10 members of the PTI1 gene family havebeen identiﬁed and share a highly conserved kinasedomain [7]. In tomato, PTI1 can physically ... isknown to phosphorylate PTI1-1 and PTI1-2 in vitro and, to a lesser extent, PTI1-3 [7]. Both kinases werepuriﬁed as HIS-tagged proteins and incubated with[c-32P]-ATP. In contrast to PTI1-4,...

Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... that E2F4 and E2F6 bind to the promoters in G0 and to someextent also in G1[55]. Furthermore, E2F4 binds to thepromoters of cyclin B1 and cyclin B2 in human tissuesaccording to ChIP, followed ... Protein kinase, key regulator of cytokinesis, mediates attachement of the mitoticspindle to the centromere, phosphorylates histone H3 during mitosisB-MYB ⁄ MYBL2 v-myb myeloblastosis viraloncogene ... research is which protein regula-tors bind to this tandem site. E2F proteins were impli-cated early on to regulate through the CDE. Analysis and identiﬁcation of factors regulating through theCHR...

Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt

... of apoptosis throughthe mitochondrial pathway. The key event in the mito-chondrial pathway is the release of proapoptotic fac-tors from the mitochondrial intermembrane space intothe cytosol, ... important intermedi-ate in ligand-induced apoptosis. tBid has been shown to be sensitive to pro-teasomal inhibitors and downregulated by activation of the epidermalgrowth factor (EGF) pathway. Here, ... time. Total cell lysateswere divided into two; one half was immunoprecipitated with anti-FLAG and blotted with anti-FLAG and anti-GFP to show total protein coim-munoprecipitation of Itch and...

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