Tài liệu Báo cáo khoa học: "Measures of Distributional Similarity" ppt
... the intersection Vqr of the supports of q and r. This is of interest from a computa- tional point of view because Vqr tends to be a relatively small subset of V, the set of all verbs. Furthermore, ... purpose of improving probability estima- tion for unseen cooccurrences. Our contribu- tions are three-fold: an empirical comparison of a broad range of measures; a classif...
Ngày tải lên: 20/02/2014, 18:20
... period of observation in the presence of both ATP and Ca 2+ were excluded from the following analyses. Visual characteristics of the Albers–Post scheme The number of peaks (i.e. the number of up–down conformational ... Histograms of the height differences between the top of SERCA and the surface of the membrane. Statistical section analy- ses of SERCA were performed with the...
Ngày tải lên: 14/02/2014, 14:20
... the inhibition of CYP activity observed in the absence of changes in protein expression in rabbit he- patocytes [22]. ROS indirectly reduced the activity of selected isoforms of CYP by inducing ... hepatic mRNA level of CD163 compared to that of sham group. Twenty-four hours after cecal ligation and puncture (CLP), the hepatic mRNA level of CD163 was similar with that of the s...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Mechanisms of amyloid fibril formation – focus on domain-swapping doc
... only after partial unfold- ing of the a-helix from the body of the b-sheet (Fig. 2C). Possible role of domain-swapping in the ‘off-pathway folding’ (OFF) model The OFF model for amyloid formation ... our understanding of the importance of different parts of the molecule and their flexibility in the process of amy- loid fibril formation often results more from a struc- tural analys...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx
... solu- tion of ThT and the fluorescence intensity of the solu- tion was measured at 482 nm. Figure 4A shows the kinetics of aggregation of a-synuclein in the presence of 100 lm MPTP and the effect of 50 ... Admin- istration of MPTP has also been shown to form aggregates of a-synuclein in nigral neurons of baboons (Papio anubis) [11]. Depletion of a-synuclein was maxi- mum in...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels pptx
... pore (PTP) [1,2], is of a sufficient size (cut-off of $ 1.5 kDa) to allow the pas- sage of solutes and water, which may also result in rupture of the outer membrane. The identity of the proteins comprising ... deamination [30]. The lack of oxida- tion of 1 mm glutamate in the presence of 5 mm succinate can be demonstrated by a complete lack of effect of rotenone on recordin...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis pptx
... interaction of both proteins or by binding of CagA PY to Csk, a negative regulator of Src [6,7]. Because Src is the primary kinase phos- phorylating CagA in the EPIYA-motifs, inhibition of Src by ... the disrup- tion of cell–cell junctions, a loss of cell polarity and the induction of pro-inflammatory and mitogenic responses (Fig. 3C). The first detected interaction part- ner of...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... Galaris 1 1 Laboratory of Biological Chemistry, University of Ioannina Medical School, Greece 2 First Division of Internal Medicine and Hepato-gastroenterology Unit, University of Ioannina Medical ... presence of relatively low amounts of oleate protected cells from stearate-induced toxicity and restored the ability of the cells to accumulate triacylglycerols. Our data suggest t...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: Kinetics of dextran-independent a-(1 fi 3)-glucan synthesis by Streptococcus sobrinus glucosyltransferase I pdf
... presence of increasing DP may be a common feature of glucansucrase. Additional studies are required to elucidate the dex- tran-dependent synthesis of glucan. As the affinity of the GBd of GTF-I ... Kodama 1 1 Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Iizuka, Japan 2 Department of Oral Microbiology, Okayama University Graduate School of Medic...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: Regulation of DNA fragmentation: the role of caspases and phosphorylation doc
... the induction of DNA fragmentation, which is one of the most typical characteristics of apoptosis. Regulators of DNA fragmentation One of the terminal processes of apoptosis is DNA degradation. During ... translocation of Bax and Bad to mitochon- dria independently of caspase activation [77,87]. Phosphorylation of caspases Phosphorylation of caspases switches the cellular...
Ngày tải lên: 14/02/2014, 22:20