... solid line), in the presence of100 lM neurotoxin (•, dotted line), in thepresence of 200 lM neurotoxin ( , dottedline) and in the presence of neurotoxin and50 lM dopamine (h, dashed line).Modulation ... protein TLS is amajor nuclear aggregate-interacting protein in hunting-tin exon 1 with expanded polyglutamine-expressingcells. J Biol Chem 283, 6489–6500.25 Uversky VN, Li J, Bower K & Fink ... of the protein on exposure todopamine [16]. In vitro experiments probably provide abetter understanding of the role of various interactingcomponents. The formation of dopamine–quinoneadducts...