... chemical structures need to be encoded using some sort of mathematical descriptors. In this work, three types of two-dimensional descriptors were used, namely phrag, fpd and shed, each one of ... shed, each one of them characterizing chem- ical structures with a different degree of fuzziness and thus complementing each other in terms of structural congenerici- ty and hoppi...
Ngày tải lên: 14/02/2014, 14:20
... digested using the abovementioned proteases (90 lg) at the optimum pH and temperature of activity of each prote- ase. In brief, digestion by Erv-A, Erv-B, Erv-C were carried out at pH 8.0 and 37 ... [15]. Sequencing of the cDNA (from mRNA) of Erv-C from the leaf of the plant in our laboratory [16], and comparison of the cDNA-derived amino acid sequence with other members...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học: Seeking the determinants of the elusive functions of Sco proteins pptx
... essential role of the Cu(II) state of Sco in the maturation of the Cu(A) center of cytochrome oxi- dase: evidence from H135Met and H135SeM variants of the Bacillus subtilis Sco. J Biol Inorg Chem 16, ... BsSco, a member of the Sco family of cytochrome c oxidase assembly pro- teins. Biochemistry 44, 2934–2942. 34 Andruzzi L, Nakano M, Nilges MJ & Blackburn NJ (2005) Spectro...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay docx
... were selected. MALDI-TOF/TOF In addition to LC-MS ⁄ MS analysis, we also completed TOF ⁄ TOF analysis of selected peaks to confirm structure using a MDS Sciex 4800 MALDI-TOF ⁄ TOFÔ instru- ment (Applied Biosystems) ... software. TOF ⁄ TOF fragmentation spectra were recorded using negative-ion linear mode with stan- dardized MS ⁄ MS acquisition and processing methods after tuning of t...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone induced by domain swapping ppt
... of the two distinct functions of TorD with the folding of TorA and possible interactions of both proteins with the MGD biosynthetic apparatus [12]. The concentration of GTP in the cytoplasm of ... in assembly and export of N-oxide reductases. Biochem Soc Trans 33, 124–126. 29 Zhang B, Zhang Y, Wang Z & Zheng Y (2000) The role of Mg 2+ cofactor in the guanine nucleotide...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... ⁄ CHR tandem element is not occupied by proteins in later cell cycle phases and is not necessary for activation of the promoters. Conclusions and perspectives What defines CDE and CHR elements? ... homologs of Caenor- habditis elegans synMuvB proteins and is composed of p130, E2F4 ⁄ 5 and DP1 ⁄ 2 and a module containing the MuvB proteins Lin-37, Lin-52, Lin-54 and chromatin...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Minor capsid proteins of mouse polyomavirus are inducers of apoptosis when produced individually but are only moderate contributors to cell death during the late phase of viral infection ppt
... levels of apoptotic markers during the late stages of MPyV infection. However, comparison of the levels of apoptotic markers and cytotoxicity during the replication of wt MPyV, and replication of ... with wt VP2 and VP3 and the fusion variants VP2–EGFP and VP3–EGFP. To further examine the membrane localization of the cytoplasmic fractions of fusion proteins, the mutu...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx
... regulation and mixed lineage leukemia. Acknowledgements We thank Imran Hussain, Sahba Kasiri, Bishakha Shrestha, Saoni Mandal and other Mandal lab mem- bers for useful discussion and critical ... evidenced by low levels of Hoxa1 , higher levels of Hoxa3 and Hoxa5 and the complete absence of Hoxa2, Hoxa4 and Hoxa6 expression [28]. These studies also demon- strated that Hoxa7...
Ngày tải lên: 16/02/2014, 14:20
Tài liệu Báo cáo khoa học: Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human pptx
... expression. The significance of understanding regulation of H3K4 methylation is exemplified by the occurrence of cancers and other diseases following mutations of H3K4 methyltransferases and demethylases or ... TRX or other HMTs [100]. Both nucleosome remodeling factor and ATP-utilizing chro- matin assembly and remodeling factor are ATP-depen- dent remodelers and carry ISW1 as...
Ngày tải lên: 16/02/2014, 14:20
Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt
... control of two copies of a canonical Meis– Pbx-binding site and a minimal TATA element, and one with two copies of the Hoxb1 auto-regulatory ele- ment (ARE) r3 element [9]. Coexpression of Meis2d and Pbx1 ... effect of the homothorax domain of Meis2 Cathy Hyman-Walsh, Glen A. Bjerke and David Wotton Department of Biochemistry and Molecular Genetics, and Center for Ce...
Ngày tải lên: 16/02/2014, 15:20