Tài liệu Báo cáo khoa học: "Minimal Recursion Semantics as Dominance Constraints: Translation, Evaluation, and Analysis" pptx

... Minimal Recursion Semantics as Dominance Constraints: Translation, Evaluation, and AnalysisRuth Fuchss,1Alexander Koller,1Joachim Niehren,2 and Stefan Thater11Dept. ... has exactly one outgoing dominance edge, and there is no weak root-to-root dominance edge.Weak. Every hole except for the last one has ex-actly one outgoing dominance edge; the last holehas ... argument handle to and and places a dominance edge from this handle to “avail-able.” In fact, the constraint is a net; it has exactlytwo readings.6.2 Qeq is dominance For all nets, the dominance...

Tài liệu Báo cáo khoa học: Seeking the determinants of the elusive functions of Sco proteins pptx

... Pseudomo-nas aeruginosa, which was reported to function in cop-per delivery to cbb3oxidase and possibly to othertypes of COX [83]. On the other hand, copper deliveryto cbb3oxidase was proposed ... NP_494755.1Ashbya gossypii Fungi Ascomycetes 1 4620854 NP_984670.2Aspergillus nidulans Fungi Ascomycetes 1 2872639 XP_662446.1Aspergillus oryzae Fungi Ascomycetes 1 5996623 XP_001824537.2Candida ... act as periplasmicthiol-disulﬁde oxidoreductases. The structural charac-terization of a Sco protein that has redox but not cop-per-binding properties, like Sco from P. putida, wasimportant as...

Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx

... Ras guanine exchangefactor and microtubule-associated protein 2, and its rolein dendrite growth – structure and function of the secondkinase noncatalytic C-lobe domainJinhong Huang1,*, Asako ... tyrosinephosphatase 13 (PTPN13, or PTP-BL ⁄ PTP-BAS) [6,7],FERM and PDZ-domain-containing 2 (FRMPD2) [8] and Ras guanine exchange factor (RasGEF) very-KIND (v-KIND, or kinase noncatalytic ... structure of the MAP2-asso-ciated RasGEF v-KIND and its dendritic tar-geting via KIND2 domain. (A) Structures ofthe v-KIND. KIND1, KIND2, coiled-coil (CC),RasN and RasGEF domains. Flag-taggedv-KIND...

Tài liệu Báo cáo khoa học: Regulation of DNA fragmentation: the role of caspases and phosphorylation doc

... ofcysteinyl aspartate-speciﬁc protease caspases. Caspases mediate apoptoticsignal transduction by cleavage of apoptosis-implicated proteins and thecaspases themselves. In the process of caspase activation, ... survival and death, and widely regulate apoptotic signal pathways.Apoptotic caspases are generally classiﬁed into twogroups: the initiator caspases (including caspase-2, -8,-9 and -10) and the ... executioner caspases (consistingof caspases-3, -6 and -7). The functional forms ofinitiator caspases directly or indirectly promote acti-vation of the executioner caspases [37,38]. Initiatorcaspases...

Tài liệu Báo cáo khoa học: RMI1 deﬁciency in mice protects from diet and genetic-induced obesity pptx

... identiﬁed as the targetgene of this mutant strain as described below). Body and organ weights as well as plasma parameters(Tables S2 and S3) were measured, and learning, mem-ory and behavioral ... modulate energyhomeostasis via regulation of cell-cycle progression inmetabolic tissues. In this study, we describe the associ-ation between RMI1 and energy homeostasis as well as the contribution ... JapanIntroductionObesity is a complex disorder and a major risk factorfor metabolic diseases such as type 2 diabetes mellitus,hypertension and cardiovascular disease. This energybalance disorder is...

Tài liệu Báo cáo khoa học: Hsp105b upregulates hsp70 gene expression through signal transducer and activator of transcription-3 pdf

... (B) Luciferase activity wasmeasured as hps70 promoter activity. Relative activity is expressed as a ratio to that of cells cotransfected with control siRNA,pGL70()2616) plasmid, and pcDNA3.1(+)myc ... expressed as ratio to that of cells cotransfected with pGL70()2616) plas-mid and pcDNA3.1(+)myc ⁄ His vector. Values represent the means ± standard deviations of four independent experiments, and asterisksindicate ... min, and then maintained at 37 °C for 8 h. Luciferase activities were then measured. Relativeactivities in (B) and (C) are expressed as ratios to that of cells transfected with pGL70()2616) plasmid...

Tài liệu Báo cáo khoa học: Protein kinase CK2 activates the atypical Rio1p kinase and promotes its cell-cycle phase-dependent degradation in yeast pdf

... leupeptin and pepstatin, twice in kinasebuffer, and used for in vitro kinase assays.In vitro kinase assaysRecombinant human protein kinase CK2 holoenzyme(0.5 U, corresponding to 1 ng; New England ... yeast strain accumulates G1cells, whereasthe number of S phase cells is drastically diminished. Itmay be noteworthy that we detected a slight imbalanceof metaphase, anaphase and telophase ... sample spot. Thecollision energy was 1 kV. Air was used as collision gas.The peptide mass ﬁngerprints were submitted to a search atthe NCBI protein database using mascot4(http://www.matrixscience.com)....

Tài liệu Báo cáo khoa học: The sequentiallity of nucleosomes in the 30 nm chromatin ﬁbre pptx

... (as) oligo-nucleotide fraction(14%) at the top of the gradient, and a well-deﬁnedband, S, of mononucleosome-size naked DNA (17%).Further MNase digestion (Fig. 3D,E) led to anincrease of band ... mononucleosomes and the band S. DNA gel electrophoresis of the fractionsfrom Fig. 3D,E showed that approximately 90% ofthe DNA in the main peak as well as the mononucleo-somes and band S are all ... al. [14] and Robinson et al. [15]? Both groups show real regularstructures, as indicated by electon micrographs. Theyboth considered two cases: a continuous helix and atwo-strand ﬁbre and they...

Tài liệu Báo cáo khoa học: Bone morphogenetic proteins in the early development of zebraﬁsh pptx

... mRNAinjection rescues sbn and snh (bmp7), but not swr(bmp2b). By contrast, smad1 rescues swr. smad1 isexpressed ventrally in gastrula as is bmp2b, and theexpression is expanded dorsally and at a higher ... suppliedmaternally and expressed throughout the embryo at abasal level (Fig. 2), whereas smad1 transcripts areonly detected from 80% epiboly. As sbn and swr[17], and sbn and snh [5], interact ... and mRNA injection, and, recently, morpholino knock-downs, have been and are the major tools for identiﬁca-tion and functional assays of BMPs. Knockdowns ofbmp2, bmp4 and bmp7 by morpholino...

Tài liệu Báo cáo khoa học: Role of receptor-mediated endocytosis, endosomal acidiﬁcation and cathepsin D in cholera toxin cytotoxicity pdf

... isolated fractions was determined bythe method of Lowry et al. [45]. Galactosyltransferase wasassayed as described by Beaufay et al. [46]. Acid phospha-tase was assayed as described by Trouet ... variousother tissues and cells has established both a cytosolic and membrane-bound localization [38], and over-expressed ARF-6 has been localized to the plasmamembrane and endosomes [39]. In ... control rats was increased 5-fold over basal levels after CT injection (Fig. 5A,cf. Basal and CT-Control). Both pepstatin A and baﬁlomycin A1 ⁄ folimycin treatment caused a  3-folddecrease in hepatic...

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