Tài liệu Báo cáo khoa học: "Different Structures for Evaluating Answers to Complex Questions: Pyramids Won’t Topple, and Neither Will Human Assessors" docx

... Association for Computational Linguistics Different Structures for Evaluating Answers to Complex Questions: Pyramids Won’t Topple, and Neither Will Human Assessors Hoa Trang Dang Information Access ... “information nuggets” to assess an- swers to complex questions. As it has become the de facto standard for evaluating such systems, the research communit...

Ngày tải lên: 20/02/2014, 12:20

... added to the C-terminal end of the 13-amino-acid peptide corresponding to the primary sequence of the Tat protein to provide a sulfhydryl group for further ligation to a ¯uorochrome or to a cargo molecule. ... NaCl/P i (pH 7 .3) and ®xed in 3.7% (v/v) formaldehyde in NaCl/P i for 5 min at room temperature. For experiments at 4 °C, the protocol was the same except that all in...

Ngày tải lên: 21/02/2014, 03:20

... ACT1 and ACT2 from different chains associate side-by-side to form an eight- stranded b-sheet, and two eight-stranded b-sheets face each other perpendicularly. In CgAKb, both eight- stranded ... we describe the crystal structures of TtAKb in two forms, Thr-bound and Thr-free, and discuss the regulatory mechanism of Thr and the struc- tural features responsible for the high the...

Ngày tải lên: 18/02/2014, 08:20

... cofactor domains of the OaPDH and TbPDH structures [13]. The superposition of sub- unit A of complex I onto subunits A, B, C of complex II and III yield rmsd-values of 0.8 A ˚ for subunit A and 1.2 ... content to Fig. 1. (A) Catalytic reaction of PDH and two intermediate states. (B) Structures and numbering of the inhibitors PEX (two resonance forms) and PEA. 6-Phospho...

Ngày tải lên: 19/02/2014, 05:20

... the former is only designed for genome analysis, whereas the latter is a general one, suitable for econometrics and time- series analysis, etc. Acknowledgements We are grateful to the referees for ... cumulative GC profile and the density distribution of CpG islands more and more accurately with decreasing t 0 . On the other hand, a smaller t 0 leads to more segmentation points...

Ngày tải lên: 19/02/2014, 07:20

... Trp1-Tat(1–9) to the EI complex was decreased. On the other hand, in the case of Ile3-Tat(1–9) the formation of the IEI complex was favored in comparison to the formation of the EI complex. Moreover, for ... site, forming ES, EI and IES complexes. The inhibitor is not able to bind to the competitive binding site. The IES complex is catalyti- cally inactive. The binding affin...

Ngày tải lên: 20/02/2014, 11:20

... Pesticides and MPTP have also been found to be mitochondrial toxins. A recent report, however, suggests that mitochondrial complex I inhibition is not required for MPP + , and other pesticides, to induce neurodegeneration ... conversion of protofibrils to fibrillar structure. Thus, in the presence of MPTP, dopamine induces a-synuclein to form fibrillar structures which are prob...

Ngày tải lên: 14/02/2014, 19:20

... (lanes 2 and 4) and 32 P-labeled ETS-1 (lanes 3 and 4) or ssDNA L (lanes 1 and 2). (B) EMSA was per- formed with EWS (lanes 2, 4 and 6) and 32 P-labeled Htelo (lanes 3 and 4), dsHtelo (lanes 5 and ... found that EWS binds to G-quadruplex con- formations and not to single- and double-stranded conformations by RGG3, we aimed to determine whether RGG3 of EWS modulates t...

Ngày tải lên: 15/02/2014, 01:20

... high sensitivity and accuracy, the lectin microarray system is the best tool for a ‘cell profiler’, and it is expected to be applicable for selection of cancer-specific lectins and for quality control ... measure- ments, we built a customized qPCR array platform for glycogene expression profiling. The qPCR array con- sists of probes and primer sets for measuring 186 gene mRNA...

Ngày tải lên: 16/02/2014, 08:20

... developed to advise on the mini- mum requirements to follow in the storage and dis- semination of experimental data in fields such as transcriptomics and proteomics, which will ultimately allow data to ... unified tool, the kineticswizard. Data querying and visualization are provided by web browser interfaces for manual access and web services for automated access to both...

Ngày tải lên: 18/02/2014, 04:20