... Yer-sinia, the increased synthesis of LcrV triggered by the activation of the system leads to the titration of LcrG,which binds LcrV in a 1 : 1 complex. In turn, thisresults in a release of the ... by the sug-gestion that pH sensing by Salmonella involves modi-fications in the assembly of the translocon, whichaffect the pH gradient within the needle, sending sig-nals to the base of the ... and in ammatory response, which isnot the case for its counterparts in other bacteria. Its interaction with macrophages induces a decrease in the production of the pro -in ammatory cytokines...