Tài liệu Báo cáo khoa học: A peptide containing a novel FPGN CD40-binding sequence enhances adenoviral infection of murine and human dendritic cells doc
Tài liệu Báo cáo khoa học: A peptide containing a novel FPGN CD40-binding sequence enhances adenoviral infection of murine and human dendritic cells doc
... A peptide containing a novel FPGN CD40-binding sequence enhances
adenoviral infection of murine and human dendritic cells
Julie L. Richards, Johanna R. Abend, Michelle L. Miller, Shikha Chakraborty-Sett, ... study, we used phage peptide
display to identify a peptide, ATYSEFPGNLKP, that
binds to CD40 and enhances adenoviral infection of mouse
a...
Tài liệu Báo cáo khoa học: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5¢-phosphate synthases of fungi and archaea docx
... riboflavin biosynthetic pathway in plants is similar
to that of eubacteria, rather than that in fungi and
archaea. In view of the close similarity between puta-
tive plant deaminases and their apparently ... archaea). We compare 2,5-diamino-6-
ribitylamino-4(3H)-pyrimidinone 5¢-phosphate synthases from the yeast
Candida glabrata, the archaeaon Methanocaldococcus jannaschii and the
eu...
Tài liệu Báo cáo khoa học: The most C-terminal tri-glycine segment within the polyglycine stretch of the pea Toc75 transit peptide plays a critical role for targeting the protein to the chloroplast outer envelope membrane ppt
... study.
Name Sequence (residues 91–100)
WT GGGAGGGGGG
polyAla *SA*AAAAA*
AGG AAA*******
GAG ****AAA***
GGA *******AAA
GAA ****AAAAAA
AGA AAA****AAA
AAG AAA*AAA***
GGD *******DDD
GGE *******EEE
GGL *******LLL
GGN ... GAA and AGA mutants were prepared using
a plasmid encoding GGA as a template and primers that
anneal to nucleotide numbers 277–314 of psToc75. Plas-
mids carrying seque...
Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt
... lysine
methyltransferases. J Biol Chem 280, 5563–5570.
53 Qian C, Wang X, Manzur K, Sachchidanand, Farooq
A, Zeng L, Wang R & Zhou MM (2006) Structural
insights of the specificity and catalysis of a viral
histone ... CREB-binding
domain of CBP [31]. The KIX domain of CBP is a
structural platform that is capable of binding several
different families of transcriptional act...
Tài liệu Báo cáo khoa học: Bacitracin is not a specific inhibitor of protein disulfide isomerase pptx
... domains, a, b, b¢, and a , a linker region x
between the b¢ and a domains, and a C-terminal acidic
extension. The a and a domains contain the CGHC
active site motif, and are sufficient alone to perform
thiol–disulfide ... the effect of bacitracin in a
variety of in vitro assays for PDI activity. On the basis
of the BPTI refolding assay and peptide oxidation
assay...
Tài liệu Báo cáo khoa học: Pharmacologic chaperoning as a strategy to treat Gaucher disease ppt
... to
lm) and stabilize just one protein and thus are gener-
ally protein and disease selective, if not specific.
Many of the clinically important Fabry disease-asso-
ciated a- galactosidase A variants ... intralysosomal
accumulation of the enzymes substrate(s) [1,2].
Although each lysosomal storage disease has unique
characteristics, generally they are progressive in nature
and le...
Tài liệu Báo cáo khoa học: Top-down MS, a powerful complement to the high capabilities of proteolysis proteomics pdf
... residue of a specific product causes
a 1 Da increase in any fragment ion containing that residue. The average mass gain of N-terminal and C-terminal fragment ions are plotted
as positive and negative, ... these fragment mass values originate
from the same molecular ions, so they must all be
characteristic of that protein’s sequence and molecular
mass value. Thus, top-down d...
Tài liệu Báo cáo khoa học: ˚ The 1.8 A crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species docx
... The Research
Council of Norway and Biotec Pharmacon ASA.
References
1 Rao MB, Tanksale AM, Ghatge MS & Deshpande VV
(1998) Molecular and biotechnological aspects of micro-
bial proteases. Microbiol ... N-terminal pro domain is autocatalytically cleaved
off when the enzyme has obtained its active conforma-
tion, and the two C-terminal domains are cleaved off
by heat treatment at...
Tài liệu Báo cáo khóa học: The PAS fold A redefinition of the PAS domain based upon structural prediction ppt
... thaliana proteins also
contain a PAC motif, and conversely that all PAC-
annotated A. thaliana proteins contain a PAS domain.
Therefore, in the case of A. thaliana,thePASandPAC
motifs are inseparable, ... future.
3
Arabidopsis
,
Escherichia
,
Caenorhabditis
and
Azotobacter
– a case study
Some of the PAS domains have been analysed in detail.
We chose four representative organis...
Tài liệu Báo cáo khoa học: Phage-display as a tool for quantifying protein stability determinants pptx
... recovered
differentially based on varying stabilities. Remarkably, we
have found that, at least in some circumstances, a quanti-
tative correlation to biophysical data can be obtained from
a statistical analysis of ... San Francisco, CA, USA
To address questions of protein stability, researchers have
increasingly turned to combinatorial approaches that permit
the rapid analysis of l...