Tài liệu Báo cáo khoa học: The sensor protein KdpD inserts into the Escherichia coli membrane independent of the Sec translocase and YidC doc

... are binding ligand independently. The tables indicate the amounts of the various cDNAs transfected into cells for each condition and apply to the data shown both above and below the table. Values ... receptors are binding ligand independently. The tables indicate the amounts of the various cDNAs transfected into cells for each condition and apply to the data sh...

Ngày tải lên: 18/02/2014, 08:20

... vivo, and the form of the collagen determines the cells synthesis and activation of MMP-2 as well as the synthesis of MT1-MMP and TIMP-1. Previously, it has been shown that the reduced level of ... in Materials and methods, and 81 lg of pro- tein was added to each well. The amount of S100A4 in the II-11b cells was 1.2% of that in the pHb-1 cells after 2...

Ngày tải lên: 18/02/2014, 11:20

... deletions of the site 1, 2 and 3 CSD sites (Fig. 7). The sequences +156 to +179 (CSD site 1) and +650 to +666 (CSD site 2) of the 5¢-UTR were deleted and the sequences +1727 to +1740 (CSD site 3) of the ... proteins were then separated by SDS/PAGE and the sizes of cross-linked proteins were calculated by subtraction of molecular masses of bound RNA fragments....

Ngày tải lên: 19/02/2014, 12:20

... sequence of the a1 subunit of PDH1 showed 31% and 32% identi- ties with the a2 subunit of PDH2 and the a subunit of the T. profundus enzyme, respectively (Fig. 3), while the b1 subunit showed 56% and ... understand the relationship between the structure and function of each subunit of this enzyme and the physiological functions of the unique prostheti...

Ngày tải lên: 20/02/2014, 01:20

... up 60–65% of the compositions of 5a and 5a-like protein and 55% of ApAFP. Of the other amino acids, Thr (13%) is the next most abundant, and there are very low amounts of aromatic and long- chain ... calls into question the functional significance of the small type I AFP in these species. Considering the levels of these AFPs in the plasma it seems unlike...

Ngày tải lên: 20/02/2014, 01:20

... invasion. The concerted process of opening of the initial double strand and the annealing of the new duplex finally results in either the replacement of the original strand or the expulsion of the invading strand, ... destabilize double strands, starting from the ends or bulges of the base- paired region, and independently of the thermody- namic stabilit...

Ngày tải lên: 14/02/2014, 19:20

... through- out the Gla proteins. From crystal structures of the Gla domain of prothrombin and factor VIIa, the placement of the seven Ca 2+ in relation to their Gla ligands is almost identical in the two proteins ... of bovine prothrombin fragment 1 in complex with Ca 2+ [41], the 10 ⁄ 12 site resides near the x-loop and the linear array of bound calcium ions of...

Ngày tải lên: 18/02/2014, 06:20

... examined the effect of AG1478 on the amounts of dually phosphorylated JNK (Fig. 5B). In PC-9 cells, AG1478 treatment decreased the expression of the MKP-1 protein and concomitantly stimulated the ... MKP-1 and MKP-2. As shown in Fig. 4B, AG1478 decreased the expression of the MKP-1 protein. As for the MKP-2 protein, however, AG1478 did not affect its expression...

Ngày tải lên: 18/02/2014, 13:20

... reversed the hypoxia-dependent downregulation of FXR. As shown in the top panel of Fig. 6A, the amount of FXR pro- tein under hypoxia was 27% of the value of the ‘norm- oxia’ control, and the treatment ... functional, neither of them lowered the FXR protein expression level (Fig. 3C). Furthermore, when FXR mRNA levels were examined, none of the HIF-a isoforms...

Ngày tải lên: 18/02/2014, 13:20

... FEBS dissect biochemical pathways that lead to these diseases and will be a major step forward in our understanding of the pathogenesis of PD and ultimately to the development of novel therapeutic ... other components of the degenerative pro- cess. The challenge for scientists is therefore to deter- mine whether there is a single pathway unifying these proteins or whether...

Ngày tải lên: 18/02/2014, 14:20