... cooperation with other transcription factors such as nuclear factor-jB and nuclear factor of activated T cells. Neutralization of COX-2 is the goal of many anti-inflammatory drugs. As an activator of COX-2 ... stimulation of human monocytic THP1 cells leads to an induction of ESE-1 mRNA expression within 1 h of exposure, reaching a peak at 4 h and leveling off after 24 h [1...
Ngày tải lên: 19/02/2014, 17:20
... users, collections, documents, and sentences, and the implementation combines custom-written code with significant use of off-the-shelf packages. The interface with commercial search engines ... engines do not provide the mechanisms needed to perform many of the simplest linguistically informed searches – e.g., seeking instances of a particular verb used only intransitively....
Ngày tải lên: 20/02/2014, 15:20
Tài liệu Báo cáo khoa học: "Liars and Saviors in a Sentiment Annotated Corpus of Comments to Political debates" pdf
... prepared for dealing with very unbalanced data? To answer these questions, we analyzed a col- lection of comments posted by the readers of an online newspaper to a series of 10 news articles, ... senti- ment annotated corpus. To measure the reliability of the sentiment anno- tations, we conducted an inter-annotator agreement trial, with two annotators. This was perform...
Ngày tải lên: 20/02/2014, 05:20
Tài liệu Báo cáo khoa học: "The Arabic Online Commentary Dataset: an Annotated Dataset of Informal Arabic with High Dialectal Content" pdf
... Computational Linguistics The Arabic Online Commentary Dataset: an Annotated Dataset of Informal Arabic with High Dialectal Content Omar F. Zaidan and Chris Callison-Burch Dept. of Computer Science, Johns ... solicit English translations of Urdu sentences from non-professional translators, and show that translation quality can rival that of professionals, for...
Ngày tải lên: 20/02/2014, 04:20
Tài liệu Báo cáo khoa học: The tandemly repeated domains of a b-propeller phytase act synergistically to increase catalytic efficiency doc
... Electrophoretic analysis of PhyH, PhyH-DI and PhyH-DII. (A) SDS ⁄ PAGE analysis of purified PhyH, PhyH-DI and PhyH-DII. Lane M, molecular weight markers; lane 1, culture supernatant of PhyH; lane 2, culture ... supernatant of PhyH-DII; lane 3, culture supernatant of PhyH-DI; lane 4, purified PhyH; lane 5, purified PhyH-DII; and lane 6, purified PhyH-DI. (B) Non-denaturing gradient PAGE...
Ngày tải lên: 14/02/2014, 15:20
Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... family kinases in health and disease – loss -of- function of BTK and ITK and the gain -of- function fusions ITK–SYK and BTK–SYK Alamdar Hussain 1,2, *, Liang Yu 1,3, *, Rani Faryal 1,2 , Dara K. ... transcriptome of both human [35] and mouse [51,53] CD8 + cells, which express very high levels of the transcription factor eomesodermin, whose own transcription is suppressed by ITK [35,51...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx
... forms of the MAPKs were produced as GST-lofMPK3 and GST- lofMPK6. However, when lofMPK3 and lofMPK6 proteins were tested for phosphorylation with OXI1, no phosphorylation of lofMPK3 or lofMPK6 ... (HR), which is local and rapid cell death at the site of patho- gen infection and limits growth of the micro-organism [22–24]. Mutants with enhanced disease resistance and exhibiting spo...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... human Cdc25C, cyclin B1 and cyclin B2 promoters is fully conserved in nucleotide sequence and function in closely related organisms such as chim- panzee, orangutan and human [25]. Timing of gene ... mechanisms of cyclin B1 and cyclin B2 cell cycle-dependent transcription began early [3,30–33]. When investigating the regulation of human cyclin B1 transcription, a potential CDE was tested...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt
... immunoprecipitated with anti-FLAG and blotted with anti-GFP to reveal Bid and tBid coimmunoprecipitation. (B) 293T cells were cotransfected with constant amounts of rLuc–Itch and various amounts of either ... coim- munoprecipitation of Itch and tBid (middle panels). The second half was immunoprecipitated with anti-GFP and blotted with anti-Myc to reveal tBid ubiquitylation (ri...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: The plasminogen activator inhibitor 2 transcript is destabilized via a multi-component 3¢ UTR localized adenylate and uridylate-rich instability element in an analogous manner to cytokines and oncogenes pdf
... vitro transcription and RNase protection assay and northern hybridization A cDNA library prepared with 1 lg of total RNA extracted from an HT1080 TET-off cell line transiently transfected with pTETBBB ... visualized and quantified with a PhosphorImager (Molecular Dynamics, Sunnyvale, CA, USA). Tet-off b-globin mRNA decay assay HT1080-TET OFF cells were transiently transfected with...
Ngày tải lên: 16/02/2014, 09:20