Tài liệu Báo cáo khoa học: "On Learning Subtypes of the Part-Whole Relation: Do Not Mix your Seeds" pdf

... Subtypes of the Part-Whole Relation: Do Not Mix your Seeds Ashwin Ittoo University of Groningen Groningen, The Netherlands r.a.ittoo@rug.nl Gosse Bouma University of Groningen Groningen, The Netherlands g.bouma@rug.nl Abstract An ... set that mixes seeds of different types fails to capture the wide variety of part-whole patterns and tuples. The re- sults ob...

Ngày tải lên: 20/02/2014, 04:20

... less sensitive to the pres- ence of the anion. These residues also modulate the conformation of unfol- ded cytochrome c, influencing its spin state and the coordination to the prosthetic group. Abbreviation CT, ... A-state (it must be noted, however, that the signal is stronger than that recorded in the presence of monovalent ani- ons [17,18]). The intensity of the 41...

Ngày tải lên: 19/02/2014, 05:20

... independently of Pbx, and does not possess the autoinhibitory function of the Hth domain. In summary, our data suggest that one function of the conserved Hth domain is to inhibit the activity of the transcriptional ... effective dominant negative. The Hth domain inhibits the activity of a linked AD To further delineate the region required for the inhibi- tory eff...

Ngày tải lên: 16/02/2014, 15:20

... mutation that has nothing to do with the cause of their cancer. Alternatively, the effect of the mutation alone is not sufficient to cause cancer without additional help from other factors. These aspects ... either does not use these residues for binding or that they are not necessary for binding as the DNA binds sufficiently hard to the other DNA binding residues. For th...

Ngày tải lên: 18/02/2014, 11:20

... regardless of the presence of uridine at other positions in the loop of helix 69 of 23S rRNA variants; (b) substitution of one U by C has no effect on the conversion of others (i.e. formation of pseudouridines ... obtained with the transition at posi- tions 1915 and 1917. These mutations had an effect on the formation of pseudouridine exclusively at the mutant posi...

Ngày tải lên: 18/02/2014, 16:20

... ligand of ERs, does not bind to any members of the ERR fam- ily [14,19]. Likewise, BPA binds only weakly to ERs and does not bind at all to any other receptors of the ERR family. BPA has the chemical ... Given that the roles of these residues definitely confirm each other, the dif- ference in their significance might be attributable to the importance and ⁄ or necessity o...

Ngày tải lên: 18/02/2014, 16:20

... each extremity of the polypeptide chain, must of necessity arise from contacts that are made outwith the active site of the enzyme. The effect of removal of the N-terminal extension The full N-terminal ... to the right and the addition of further residues at the N-terminus or beyond residue 34 of the inhibitory segment is superfluous. However, in the case o...

Ngày tải lên: 19/02/2014, 00:20

... that the less active SP isoform becomes ‘active’ when a small amount of QAE1 is added. In contrast, it does not become active on the addition of another SP isoform. These results suggest that the ... alignment of nfeAFPs The complete amino acid sequences of the 13 isoforms of nfeAFP were determined based on the cDNA A B Fig. 2. (A) HPLC purification of the isoforms...

Ngày tải lên: 19/02/2014, 16:20

... changes in the concentration of P i do not modify the partition (Fig. 3A). However, the presence of P i considerably affects the dynamics of the system. Indeed, in the presence of 10 m M P i , the model ... first, the activating interaction of AdoMet with TS may attenuate the changes in the flux of threonine due to a modification of the level of AdoMet....

Ngày tải lên: 20/02/2014, 02:21

... Equal mobilities of the radioactive and the protein-containing bands indicated covalent attachment of DNA to the enzyme. The yield of the photochemical cross-linking reaction was calculated as the ratio of the ... expressed as the oxoG residues and 5 n M enzyme. The incubation was performed at 37 °C. The reaction was stopped by the addition of 3 lL 7,8 of for...

Ngày tải lên: 20/02/2014, 11:20