Tài liệu Báo cáo khoa học: Control of the coagulation system

Tài liệu Báo cáo khoa học: Control of the coagulation system by serpins Getting by with a little help from glycosaminoglycans pptx

... concentration of AT and the rates of interaction in the presence and absence of hep- arin pentasaccharide (Table 1), one can calculate that the half-life of enzyme activity in the absence of hep- arin ... the mechanism of action of these serpins and have signiﬁcantly added to a wealth of biochemical and biophysical studies carried out previously. A major featur...

Ngày tải lên : 20/02/2014, 02:21

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Tài liệu Báo cáo khoa học: Motion of the Ca2+ -pump captured ppt

... concentrations are summarized in Fig. 4A. The data clearly show that a sharp peak (quick up–down conformational change of SERCA) was rarely observed and that the lifetime of the elevated conformation ... from the cytoplasm by the Ca 2+ -pump (Ca 2+ -ATPase) [3,4], which accu- mulates Ca 2+ inside the SR against its concentration gradient. The importance of the SR C...

Ngày tải lên : 14/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis pptx

... during the course of infection, as indicated. H. pylori expresses several adhesins such as BabA, BabB, SabA, AlpA and AlpB, as well as OipA, which mediate apical binding of the bacteria (1). Attached ... phos- phorylating CagA in the EPIYA-motifs, inhibition of Src by CagA PY generates a classical negative feedback- loop that appears to control the amount of intracellu-...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: Upregulation of the a-secretase ADAM10 – risk or reason for hope? docx

... coim- munoprecipitation, tetraspanin 12 was identiﬁed as an interaction partner for ADAM10 that enhances a- secretase shedding of APP, probably by regulating matu- ration of the prodomain of ADAM10 [22]. The ... aetiology of AD. ADAM10 and tumour necrosis factor a (TACE): the ill-matched couple Three members of the ADAM family have been shown to act as a- secretase [...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Myristoylation of the dual-speciﬁcity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis pdf

... sites in the cytoplasm. Signaling from internal membranes is now considered to be an important aspect of the spatial and temporal regulation of signaling pathways, e.g. the Ras ⁄ MAPK pathway [38,39]. ... dephosphorylate the Tyr and Thr residues in the activation loop of MAPKs and thereby attenuate signaling [17,19]. In addition, there is a group of low molecular mass...

Ngày tải lên : 16/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Regulation of the members of the mammalian heat shock factor family doc

... 2435– 2447. 100 Tanabe M, Sasai N, Nagata K, Liu XD, Liu PC, Thiele DJ & Nakai A (1999) The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing. ... C-terminal activator domain in yeast heat shock factor: independent control of transient and sustained transcriptional activity. EMBO J 12, 5007–5018. 35 Nakai A, Tanabe M...

Ngày tải lên : 18/02/2014, 04:20

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Tài liệu Báo cáo khoa học: Structure of the putative 32 kDa myrosinase-binding protein from Arabidopsis (At3g16450.1) determined by SAIL-NMR docx

... PA-oligosaccharides, GalNAca1-3(Fuca1-2)Galb1-3(Fuca1-4)GlcNAcb1-3Galb1- 4Glc-PA and Neu5Aca2-6Galb1-4GlcNAcb1-2Mana1- 6(Neu5Aca2-3Galb1-3(Neu5Aca2-6)GlcNAcb1-4(Neu5Aca2- 6Galb1-4GlcNAcb1-2)Mana1-3)Manb1-4GlcNAcb1-4Glc- NAc-PA ... glycan Neu5Aca2-6Galb1-4GlcNAcb1-2Mana1-6(Neu5- Aca2-3Galb1-3(Neu5Aca2-6)GlcNAcb1-4(Neu5Aca2-6Galb1- 4GlcNAcb1-2)Ma na1-3)Manb1-4GlcNAcb1-4GlcNA-PA was used as a...

Ngày tải lên : 18/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Switching of the homooligomeric ATP-binding cassette transport complex MDL1 from post-translational mitochondrial import to endoplasmic reticulum insertion pptx

... Fullerton, CA, USA). K m ATP values were derived by fitting the data to the Michaelis–Menten equation. Specific inhibition of the ATPase activity was ana- lyzed at various concentrations of vanadate, ... modification is an artifact of Edman degradation or whether this deami- dation is catalyzed by a N-terminal amidase during mitochondrial translocation. We next examined the m...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Analysis of the molecular dynamics of medaka nuage proteins by ﬂuorescence correlation spectroscopy and ﬂuorescence recovery after photobleaching doc

... primers 5¢-GGAGATCTAAAATGGACGACTGGGAGGAAGA-3¢ and 5¢-GCGAATTCGTTGAAAACTTTTAATTATCA GGAGAAAAC-3¢,5¢-CGAGATCTAGCATGTCAGACG TGGAGTCTGGA-3¢ and 5¢-GCGAATTCGCAACCAAA GACAACCTGGTTTTAATGTTTTGA-3¢, and 5¢-CGAG ATCTGAAATGAACGAGCTGCGTATGCCGAA-3¢ ... 5¢-GCGCTAGCTAAT ACGACTCACT ATAG GGA GATC TAAA ATGG AC GAC TGGGAGGAAGA-3¢ and 5¢-GCGAATTCGTTGAAA ACTTTTAATTATCAGGAGAAAAC-3¢. This PCR frag- ment has a T7...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Modulation of the enzymatic efﬁciency of ferredoxin-NADP(H) reductase by the amino acid volume around the catalytic site pptx

... (5¢-GACAA CACTTTTGTCTACATGTTGGGACTGAAAGG-3¢)or FNRC266M (5¢-GACAACACTTTTGTCTACATGATGG GACTGAAAGG-3¢) and FNRlw1 (5¢-GTAATCTATCTA CAGAATACAGGAGGGTGATA-3¢) as primers and plas- mid pCV105 [63] as template. In addition, ... oligonucleotides FNRup1 (5¢-AACAAGTTCAAACCTAAGGAACCATA CG-3¢) and FNRC266Llw (5¢-CCTTTCAGTCCCAACA TGTAGACAAAAGTGTTGTC-3¢) or FNRC266Mlw (5¢ -C CTTTCAGTCC CATCATGTAGACAAAAGTGT...

Ngày tải lên : 18/02/2014, 17:20

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