Tài liệu Báo cáo khoa học: Physiological relevance of the endogenous mono(ADP-ribosyl)ation of cellular proteins doc

... al. mono(ADP-ribosyl)ation reactions in mammals FEBS Journal 272 (2005) 4565–4575 ª 2005 FEBS 4575 MINIREVIEW Physiological relevance of the endogenous mono(ADP-ribosyl)ation of cellular proteins Maria ... [17,18]. In several of the ARTs, the replacement of this second glutamate abolishes the ability of these transferases to use arginine as acceptors, thus furt...

Ngày tải lên: 20/02/2014, 02:21

... the relationship of these two molecules is still largely unknown. The aim of the current study was to investigate the potential involvement of nucleolin ⁄ C23 in the antiapoptotic mechanism of Hsp70. ... the condensation and fragmentation of their nuclei. The percentage of apoptotic cells was calculated as the number of apoptotic cells divided by the total numb...

Ngày tải lên: 16/02/2014, 09:20

... [26]. The initiator Met at the N-terminus was removed by the bacterial cell for all these proteins except for RTnI 96)181 . Inhibition of Mg-ATPase of actomyosin by TnI-fragments The inhibition of ... understand the biological significance of the differ- ence in TnI–TnC interactions, we compared the ability of TnC to neutralize the inhibitory effects of the C-te...

Ngày tải lên: 20/02/2014, 01:20

... returns true if the morph of the descendant of d e is the same as the morph of the descendant of d s , or if both descendants have canonical mentions with an exact string match; the 3 We remove ... parse trees. The set of nonterminal labels associated with each word is the set of labels of the nodes for which that word was the head. For example, in the lexi...

Ngày tải lên: 20/02/2014, 09:20

... to the magnesium binding site M3 [4]. Fig. 4. The influence of Mg 2+ on the kinetic properties of APase from E. coli. The influence of Mg 2+ on the kinetic properties of APase from E. coli inthepresenceofaZn 2+ to ... influence the equilibrium concentration of the subunits. Deviation from linearity in the dependence of the Mg 2+ ion concentration It has been determi...

Ngày tải lên: 21/02/2014, 00:20

... embryo- genesis, all the evidence suggests that sex determination might disobey the conventional rules of evolutionary conservation. The common picture emerging here is that the genes at the top of the cascade ... result, the common emerg- ing picture is that the genes at the top of the cascade are not conserved, whereas the downstream genes have homologues in a mu...

Ngày tải lên: 14/02/2014, 19:20

... activity was defined as the reduction of 2 lmolÆ- min )1 of metronidazole (corresponding to the decarboxyl- ation of 1 lmolÆmin )1 of pyruvate on the assumption that the bleaching of the chromophore ... under- standing of the metabolism of H. thermophilus. Indeed, this would enable the kinetic analysis of the POR reac- tions in both directions. In particular, t...

Ngày tải lên: 16/02/2014, 09:20

... [8,9]. One of the interesting features of the plant PSs is the presence of a conserved 24 residue insertion in the sequence [9]. This sequence of amino acids, which is missing in the sequence of bacterial ... pantothe- nate from low amounts of pantoate [9]. Here, we report the results of the structural studies of the panto- ate-bound form of the N-terminal...

Ngày tải lên: 16/02/2014, 09:20

... than other regions of the protein, implying that the TCPCP(5–9) sequence at the N-terminus might contribute to the dynamics of the b-domain of hGIF. However, the structure of the b-domain of hGIF ... opposite side of the two rings. The specific folding of the TCPCP(5–9) sequence, together with the constraints from the metal–thiolate cluster, made the pep...

Ngày tải lên: 16/02/2014, 15:20