Tài liệu Báo cáo khoa học: Nop53p, an essential nucleolar protein that interacts with Nop17p and Nip7p, is required for pre-rRNA processing in Saccharomyces cerevisiae pdf

... processing in S. cerevisiae FEBS Journal 272 (2005) 4450–4463 ª 2005 FEBS 4463 Nop53p, an essential nucleolar protein that interacts with Nop17p and Nip7p, is required for pre-rRNA processing in Saccharomyces ... play an important role in ribosome biogenesis, possibly related to the exosome function. Results Nop53p interacts with the pre-rRNA...

Ngày tải lên: 20/02/2014, 01:20

... while cytoplasmic membrane blebbing and fragmentation and apoptotic redistribution of actin were strongly inhibited in a cell line containing a caspase-resistant BAP31 [9]. Interest- ingly, the cytosolic ... Ó FEBS 2003 and/ or additional protein variants. We therefore re-analysed the data with a smaller database, containing only human actin or human myosin entries, and MS/MS spe...

Ngày tải lên: 20/02/2014, 23:20

... signalling. Among the functionally important protein components of these microdomains are transmembrane adaptor proteins, containing in their intracellular domains tyrosine residues that can be ... phosphorylated and bind other cytoplasmic signalling proteins. The most important leukocyte transmembrane adaptor protein is LAT (linker for activation of T cells), which is critica...

Ngày tải lên: 18/02/2014, 04:20

... Consistent with this, our analysis of cellular membranes washed with high-salt solution establishes that RNF13 is indeed an integral membrane protein. This is consistent with data showing that RNF13 is ... protease-associated domain, a structure found in numerous proteases and implicated in protein binding, and C-terminal RING finger and PEST domains. Homologous...

Ngày tải lên: 18/02/2014, 08:20

... current drugs, combination therapy is being increasingly employed. Artemisinin, which is obtained from the plant Artemisia annua ,is an extremely effective antimalarial, and this drug, or its derivatives ... salivary glands for onward transmission into another host (Fig. 1A). This form of the parasite is found in the salivary glands after 10–18 days and thereafter the mosquit...

Ngày tải lên: 18/02/2014, 16:20

... ambiguity in English), and therefore the risk of misclusterings is lower. Thirdly, this problem can be reduced by consider- ing longer contexts which tend to be less ambigu- ous. That is, by choosing ... This is achieved by assuming that the word pair consisting of the left and right neighbor of a particular token is characteristic of the part of speech at this position...

Ngày tải lên: 20/02/2014, 12:20

... the extensions described in this paper turn it into an in- dexing and search tool for certain kinds of treebanks, complementary to existing treebank search engines. Section 2 briefly introduces the basic ... it into a tool for indexing and searching certain kinds of tree- banks, complementary to existing treebank search engines. In particular, the paper dis- cusses the motivati...

Ngày tải lên: 20/02/2014, 12:20

... Cognitive Science and The Ohio State Departments of Computer and Information Science and Linguistics grammar (using compiled knowledge) which is then used to realize the actual utterance. The syntactic/semantic ... socio-pragmatic context). This research investigates bringing socio-pragmatic knowledge to bear during the parse, while maintaining a domain independent grammar an...

Ngày tải lên: 20/02/2014, 21:20

... parse(s) of an input string from the implausible ones. In stochastic language processing, it is assumed that the most plausible parse of an input string is its most probable parse. Most instantiations ... reliability. For DOP this means that, instead of exhaustively calculating all parses with all their derivations, we randomly calculate N parses of an input string (by...

Ngày tải lên: 22/02/2014, 10:20

... function in neurons, and reinforce the suggestion that tau is itself involved in intracellular sig- nalling pathways ⁄ mechanisms. As its interaction with Fyn is important for tau localization in neurons, ... [20,21]. Using mutant forms of full-length tau, we show that direct interaction with Fyn-SH3 is mediated predominantly by Pro216 in tau. In addition, we show...

Ngày tải lên: 14/02/2014, 14:20