Tài liệu Báo cáo khoa học: Hyperactive antifreeze protein in flounder species The sole freeze protectant in American plaice docx

... et al. Hyperactive antifreeze protein in fish FEBS Journal 272 (2005) 4439–4449 ª 2005 FEBS 4449 Hyperactive antifreeze protein in flounder species The sole freeze protectant in American plaice Sherry ... protect the fish down to the freezing point of seawater. The absence of the small type I AFPs in the American plaice argues that these single...

Ngày tải lên: 20/02/2014, 01:20

... restrict the available dihedral angles between the participating Table 1. Amino acid frequencies (%) in a-amylase linkers, in a set of globular proteins, in the Swiss-Prot databank and in intrinsically unstructured ... near the N- and C-termini of the linkers: this suggests that a mobile connection with both the catalytic domain and the binding module is required for th...

Ngày tải lên: 14/02/2014, 18:20

... starting points for invasion. The concerted process of opening of the initial double strand and the annealing of the new duplex finally results in either the replacement of the original strand or the ... repulsive interactions within the RNA molecule. The protein thereby smooths the folding energy landscape. The direction of the RNA folding reaction (either annealin...

Ngày tải lên: 14/02/2014, 19:20

... assembly. In the first model, both hydrophobic translocators exist in oligomeric form, with the major partner inserted stably into the membrane, whereas the minor protein is the link with the V antigen. ... stoichiometry in other species still awaits further study. The hydrophilic translocator: the V antigen The third component of the translocation apparatus is a...

Ngày tải lên: 14/02/2014, 22:20

... cadherin interacts with F-actin via b-catenin and a-catenin; b-catenin binds to cadherin and a-catenin, which in turn interacts with F-actin (Fig. 3A) [24]. Thus b-catenin plays a pivotal role in the ... cadherin–catenin complexes within each cell and by cadherin–cadherin interactions between the two cells. The interkinetic cells adhere to each other via cadherin–catenin complexes,...

Ngày tải lên: 16/02/2014, 09:20

... Switzerland Introduction The serine endopeptidase elastase-2 (human leukocyte elastase) is a basic protein with an isoelectric point of 10.5. Eighteen of the 19 arginine residues present in the protein ... glycosaminoglycan binding the enzyme at different sites, may cause interference with the natural protein inhibi- tors of elastase-2, particularly the a-1 peptidase inhib...

Ngày tải lên: 16/02/2014, 14:20

... a-defensins, b-defensins, and h-defensins. Defensins are widely expressed [8], and in mammalian species more than 100 have been identified. Depending on the cell, they will exert their function either in the intracellular ... defined mechanism involving mitogen-activated protein kinase p38 inactivation [85]. This immunomodulatory effect of the TLR response is mediated through the...

Ngày tải lên: 18/02/2014, 06:20

... membrane binding. In human proteins, protein S binds to the protein C Gla domain. Although this interaction has been mapped to Gla regions C-terminal to the 23 site [31,32], it may still in uence the interaction ... mem- brane binding affinity enhancement by minor increases in the overall on-rate and ⁄ or minor decreases in the overall off-rate. The results obtained in...

Ngày tải lên: 18/02/2014, 06:20

... substrate on the active site of HYD Js The substrate binding pocket in the active site was inves- tigated based on the homology model to obtain more information on substrate binding in HYD Js . The orien- tation ... In HYD Js , the hydrophobic interactions within the three SGLs in the substrate binding pocket seem to be important for the substrate specificity, as obse...

Ngày tải lên: 18/02/2014, 08:20

... present in the neuroendocrine organ, a puzzling question remains unanswered: how are these peptides distributed in the different cells of the X organ–sinus gland system? In other words, what is the ... the results obtained in the crayfish Orconectes limosus, showing that l-isomer of CHH is always present in the different parts of the d-CHH cells, in decreasing amoun...

Ngày tải lên: 18/02/2014, 11:20