Tài liệu Báo cáo khoa học: Enlarging the gas access channel to the active site renders the regulatory hydrogenase HupUV of Rhodobacter capsulatus O2 sensitive without affecting its transductory activity docx

... 77, 7347–7351. O 2 sensitivity of the regulatory hydrogenase HupUV O. Duche ´ et al. 3908 FEBS Journal 272 (2005) 3899–3908 ª 2005 FEBS Enlarging the gas access channel to the active site renders the regulatory hydrogenase ... In the case of the regulatory HupUV protein, our results favour the hypothesis of Volbeda et al. [25], which explains...

Ngày tải lên: 20/02/2014, 01:20

... the protein content of active ⁄ dephosphorylated b-catenin without changes in total b-catenin, suggesting that a-defensins activate the b-catenin signaling pathway. We then studied the role of ... from granules of leukocytes and are implicated in inflammatory and fibrotic lung diseases. In the present study, the effects of a-defensins on the proliferation and collagen sy...

Ngày tải lên: 18/02/2014, 06:20

... initially to the a domain, thereby lead- ing to formation of the M 4 a cluster prior to formation of the M 3 b cluster, demonstrating that the individual binding constants of divalent metal ions for the a ... of the a domain of rhMT-1a, showing the connectivities of the four divalent metal cations to the 11 cystei- nyl sulfurs. The numbering of the...

Ngày tải lên: 19/02/2014, 00:20

... NADH generation, due to amino acid biosynthesis. Much of the generation of NADH during amino acid biosyn- thesis takes place in the mitochondria. Because of the block in the respiratory chain caused by the addition of ... biosynthesis of sterols and fatty acids, heme ⁄ hemoproteins, NAD, and uracil [7,8]. The abil- ity to translocate ATP produced in the cytoplasm i...

Ngày tải lên: 19/02/2014, 02:20

... Attempts to clarify the stoichiometry by adding a small amount of the purified dioxygenase to the reaction mixture with a large excess of the purified enzyme reported here to avoid the formation of 2,5-pyridinedicarboxylic ... time. The peak at 268 nm was assigned to 2,5-pyridinedicarboxylic acid based on the wavelength [10]. Purification and properties of the pur...

Ngày tải lên: 19/02/2014, 16:20

... the activity of the PTS system and thereby result in further increases in hexose phosphate pools. The decreased LDH activity may contribute further to this effect by causing an accumulation of ... by the second gene in the las operon (Fig. 1). In order to obtain strains with increased PK activity an additional copy of the pyk gene was recombined into the TP901-1...

Ngày tải lên: 19/02/2014, 17:20

... /'YES'@[102]. The different number of positions considered to the left and right of the markers in our training corpus, as well as the nature of the features selected (there are many more ... classification task. 7 The nai- ve Bayes (NB) algorithm estimates the conditional probability of a set of features given a label, using the product of the...

Ngày tải lên: 20/02/2014, 15:20

... constraints )to design the structural representation for a given string of terms (because its topology is indepen- dent of the derivation tree of the grammar), as well as the nature of the correspondence ... indeed possible to change the label of node 2 to something else, or to move the node to the right of node 4, or even to exclude the node a...

Ngày tải lên: 22/02/2014, 10:20

... becomes available to the community in an accessible and utiliz- able form. Thus, the data flow from the experiment to the consumer performing the analysis, the comparison or the set-up of computer models ... (http://sabio.h -its. org/ webservice.jsp) provide flexible programmatic access to the data, allowing users to write clients to customize and automate access...

Ngày tải lên: 18/02/2014, 04:20

... it to the lysosome. Once mutated GC is localized to the lysosome, the glucosylceramide substrate is able to displace the inhibitor and allow the enzyme to turn over glucosylceramide, owing to Fig. ... binding to the folded mutant GC enzyme population in the ER, shift the equilibrium towards folding allowing mutant GC to be trafficked to the Golgi and on to...

Ngày tải lên: 18/02/2014, 16:20