Tài liệu Báo cáo khoa học: Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase pdf

... Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase Ina Catrein, Richard Herrmann, Armin Bosserhoff ... N-terminus instead of a free amino group [32]. Therefore, the asparagine in position 26 was labeled within the intact protein at its a- am...

Ngày tải lên: 19/02/2014, 18:20

... complexes. This multimerization can involve either of the PDZ domains, as for example in glutamate receptor interacting protein 1 (GRIP1) [55] or inactivation no afterpotential D (INAD) protein [56]. ... remodelling is a crucial process occurring during cell migration and invasion in various physiological (i. e. embryonic development, ovulation, angiogenesis, wound healing) and path...

Ngày tải lên: 18/02/2014, 04:20

... reoxygenation but is ineffective at maintaining glutathione levels during hypoxia Glutathione is one of the main antioxidant compounds in the cell, and it is also essential for DNA synthesis and repair ... this a- keto acid is associated with protective effects against hypoxia and reoxygenation. This is mainly ascribed to its ability to maintain redox status [17], intervening in th...

Ngày tải lên: 18/02/2014, 16:20

... activity N-acetyl-Leu-Glu-His-Asp-pNA No activity No activity No activity N-acetyl-Val-Glu-Ile-Asp-pNA No activity No activity No activity N-acetyl-Ile-Glu-Thr-Asp-pNA No activity No activity No activity IC 50 in nM for ... K) for papain and ervatamin -A also reveal that side chain conformations of the S2 subsite residues are less flexible in papain than in erv...

Ngày tải lên: 18/02/2014, 16:20

... USA) for expression as a Gal4 DNA-binding domain fusion protein. This bait was transformed into an AH 109 yeast strain and used to screen a human brain two-hybrid cDNA library from Clonetech as ... proteins are of particular relevance from the clinical point of view. Anp32 proteins are powerful inhibitors of phos- phatase 2A (PP 2A) , a major serine ⁄ threonine phospha- tase in...

Ngày tải lên: 18/02/2014, 17:20

... equal to those for maltooligosaccharides. Despite having similar folds, the sugar-binding site of the N-domain part of TvuCMBP and other bacterial sugar-binding pro- teins are strikingly different. ... critical in determining the specificity of the bacterial sugar-binding proteins. Evaluation of the binding affinities by fluorescence measurements The K d values of TvuCMBP for...

Ngày tải lên: 19/02/2014, 00:20

... derivation and in a variety of orders. This means that compar- ing all of the dependencies in a particular state may require traversing the entire sub-derivation at that point. Parsing is already ... Curran, 2004b). 2.3 n-best parsing and reranking Most parsers use dynamic programming, discard- ing infeasible states in order to maintain tractability. However, constructing an n-b...

Ngày tải lên: 19/02/2014, 19:20

... suitability of the available parallel training data. Domains (e.g., newswire vs. blogs) may vary widely in their lexical choices and stylistic prefer- ences, and what may be preferable in a general ... selecting rele- vant phrases for translation. Matsoukas et al. (2009) introduced assigning a pair of binary features to each training sentence, indicating sentences’ genre and col...

Ngày tải lên: 19/02/2014, 19:20

... with variation of less than 15%. Proteins Aerobiosis Anaerobiosis Anaerobiosis + MV + Activity HD formation H 2 formation Activity HD formation H 2 formation Activity HD formation H 2 formation HupUV ... HupUV sensitive to O 2 inactivation. Also, in contrast with the wild -type protein, the mutated protein exhibited an increase in hydrogenase activity after reductive activation...

Ngày tải lên: 20/02/2014, 01:20

... ChlM catalysis by accelerating the formation and breakdown of the catalytic intermediate, providing a kinetic link between the first two reactions of chlorophyll biosynthesis, with the signalling ... of the intermediate occurs much earlier (Fig. 3B), and intermediate accumulation occurs within the 2 ms dead time of the instrument. This dramatic acceleration in formation of the in...

Ngày tải lên: 20/02/2014, 02:21