Tài liệu Báo cáo khoa học: Binding of ligands originates small perturbations on the microscopic thermodynamic properties of a multicentre redox protein pptx

... FEBS Binding of ligands originates small perturbations on the microscopic thermodynamic properties of a multicentre redox protein Carlos A. Salgueiro 1,2 , Leonor Morgado 1,2 , Bruno Fonseca 1,2 , ... with data for the isolated cytochrome shows that binding of ligands causes only small changes in the reduction potentials of the haems and their...

Ngày tải lên: 19/02/2014, 17:20

... translation. Half of the translations are correct translations (A and B), while a third are partially correct translation (P). Notice that it is a common practice to translate only the surname ... outside of translations. In Figure 1, the translation 艾美獎 (ai mei jiang) are labeled as B I I, while all other Chinese characters are labeled as O. An additional tag of E...

Ngày tải lên: 19/02/2014, 19:20

... knowledge, the consequence is that a large quantity of analyzed language data can be found on the Web. In many cases, the data is richly annotated and exists for many languages for which there would otherwise ... limited annotated data. The resource, the Online Database of INterlinear text (ODIN), makes this data available and provides additional annotation and structure, ma...

Ngày tải lên: 22/02/2014, 02:20

... sheep and goats. The main characteristic of the disease is the accumu- lation of an abnormal prion protein (PrP Sc ), thought to be the only infectious agent associated with prion neurodegeneration ... molecular masses are the di- and mono-glycosylated isoforms and the band with the lowest molecular mass is nonglyco- sylated PrP C . Quantification of the three protein...

Ngày tải lên: 19/02/2014, 02:20

... MT1-MMP activation of MMP-2, can also take part in the second autoactivation step and function as an activator by promoting conversion of the 64 kDa intermediate to the fully active 62 kDa form. ... Further, autoactivation of the active 62 kDa form to a C-terminally truncated 45 kDa form was also inhibited by TIMP-1. Investigation of mechanisms that may explain the increas...

Ngày tải lên: 18/02/2014, 11:20

... fungi and archaea). We compare 2,5-diamino-6- ribitylamino-4(3H)-pyrimidinone 5¢-phosphate synthases from the yeast Candida glabrata, the archaeaon Methanocaldococcus jannaschii and the eubacterium ... riboflavin biosynthetic pathway in plants is similar to that of eubacteria, rather than that in fungi and archaea. In view of the close similarity between puta- tive plant deaminases...

Ngày tải lên: 18/02/2014, 18:20

... obtain cDNAs encoding M25L–elafin and M63L–trap- pin. For this purpose, forward primers 5¢-CGACTCGA GAAAAGAGCGCAAGAGCCAGTCAA-3¢ and 5¢-CGAC TCGAGAAAAGAGCTGTCACGGGAGTTCCT-3¢ were used for amplification ... Pr3 was assessed by adding a constant concentration of enzyme to increas- ing concentrations of elastin, stirring for 10 min, centrifugating the suspensions and measuring the concent...

Ngày tải lên: 19/02/2014, 07:20

... concentrations of CCK-8, CCK-8-NS and eugenin. Con- tractions were measured on a Maclab data recorder (Maclab, Castle Hill, New South Wales, Australia) and expressed as a percentage of the maximal ... separation. MS and MS ⁄ MS data on the components of all HPLC fractions indicate the presence of a variety of lipid, sugar and phosphate Fig. 1. The young of Macrop...

Ngày tải lên: 19/02/2014, 16:20

... focus on the transcriptional unit coding for the class A transcript, and refer to it and its regula- tory regions as the Abd-B domain. The expression pat- tern of Abd-B is regulated by a set of large ... abdominal segments A6 and A7 . Although the iab-5 cis-regulatory region is also in an active conformation in A6 , only iab-6 is presumed to contact the Abd-B promoter...

Ngày tải lên: 20/02/2014, 01:20

... proceeds with similar activity at both individual sites; cleavage rates are virtually identical, ligation rate constants vary by a factor of only about 2.5. Alteration of RNA sequence by the twin ribozyme HP–TWRJ The ... from ligation of the 15-mer produced by cleavage in the first step of the reaction to the added 20-mer fragment S20 cp. This illustrates that ligation at...

Ngày tải lên: 20/02/2014, 01:20