Tài liệu Báo cáo khoa học: The Ets transcription factor ESE-

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

... examining the role of GIF in AD, linked to its initial discovery as a factor deﬁcient in the AD brain. There remains no clear con- sensus on the role of GIF in the pathogenesis of AD, and therefore ... interest in the roles of the entire MT family in the brain, with particular focus on the role of these proteins in the injured or neurodegenerative bra...

Ngày tải lên : 16/02/2014, 15:20

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Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx

... Values are the mean of six replicates. The speciﬁc uptake was determined by subtracting the uptake counts in the absence of inhibitor from the uptake counts in the presence of cocaine or S-cita- lopram, ... To distinguish total binding from non-speciﬁc binding, cells were incubated for 10 min in either PBSCM alone or PBSCM containing 200 lm cocaine for inhibition of...

Ngày tải lên : 14/02/2014, 21:20

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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt

... 2A). The zinc ions are required for the structural integrity of the protein, as mutation of any of the cysteine residues involved in zinc coordina- tion results in protein unfolding [22]. The ... to the KIX domain of the cAMP response element-binding (CREB) binding protein (CBP) [23], a peptide from the Win motif of MLL1 bound to the WD40 repeat protein, WDR5 [...

Ngày tải lên : 16/02/2014, 14:20

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Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf

... simultaneously interacts with the main phosphate of the substrate [32]. The closer positioning of the N-terminus to the main protein body is essential for the activity and, together with the 87–104 ... 23 diminished the midpoint of the thermal denaturation curve (T m )by7 °Candthefree energy of unfolding (DG U )by1 1kJÆmol )1 . These values are in very close agre...

Ngày tải lên : 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: "An ISU Dialogue System Exhibiting Reinforcement Learning of Dialogue Policies: Generic Slot-ﬁlling in the TALK In-car System" pot

... Exhibiting Reinforcement Learning of Dialogue Policies: Generic Slot-ﬁlling in the TALK In- car System Oliver Lemon, Kallirroi Georgila, and James Henderson School of Informatics University of Edinburgh olemon@inf.ed.ac.uk Matthew ... in- car” information system). Then we describe the major components of the system and give examples of their use. We then discuss the imp...

Ngày tải lên : 22/02/2014, 02:20

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Tài liệu Báo cáo khoa học: Steady-state and time-resolved ﬂuorescence studies of conformational changes induced by cyclic AMP and DNA binding to cyclic AMP receptor protein from Escherichia coli ppt

... decreases by about 8 A ˚ to 18.7 A ˚ on binding of cAMP to the anti-cAMP-binding sites of the protein. The distance between the sulfur atom of Cys178 and the C9–C10 bond of the indole ring of Trp85, ... that the binding of cAMP to anti-cAMP-binding sites of CRP leads to the increase in the structural dynamic motion of at least Trp13, which is located in...

Ngày tải lên : 20/02/2014, 23:20

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Tài liệu Báo cáo khoa học: "An Information-Theory-Based Feature Type Analysis for the Modelling of Statistical Parsing" docx

... sequence containing the leaf nodes of the partial parsing tree rooted by the current node, representing the final objectives to be derived from the current node. 4.2 The corpus used in the experiment The ... headword of the node. In the following, the units of PIQ are bits. Conclusion Among the feature types in the same structural position of the...

Ngày tải lên : 20/02/2014, 18:20

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Tài liệu Báo cáo khoa học: "ENGLISH WORDS AND DATA BASES: HOW TO BRIDGE THE GAP" pdf

... picture of the PHLIQA set-up, by ignoring these intermediate levels. Given the distinctions just introduced, the problem raised by the discrepancy between the Eng- lish lexicon and the set of ... independently of each other (one on the basis of the possible Eng- lish questions about the subject-domain, the other on the basis of the structure of...

Ngày tải lên : 21/02/2014, 20:20

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Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

... tissue, although they are not obese [15]. The expression of in ammatory cytokines (tumor necrosis factor- a, interleukin-6 and interleukin-1b) was increased in the adi- pose tissue of ANGPTL2 transgenic ... in ammation induces a state of ‘leptin resistance’ in obese animals and humans resulting in development of hyperleptinemia. Similarly, hyperleptinemia is a consequen...

Ngày tải lên : 14/02/2014, 22:20

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Tài liệu Báo cáo khoa học: Diol dehydratase-reactivating factor is a reactivase – evidence for multiple turnovers and subunit swapping with diol dehydratase pdf

... (AdePeCbl) (an inactive coenzyme analog containing the adenine ring in the upper axial ligand; a model of intact coenzyme, AdoCbl) in the presence of ATP and Mg 2+ at a molar ratio of the reactivating factor ... damaged cofactor remains tightly bound to the active site. The DD-reactivating factor reacti- vates the inactivated holoenzyme in the presence of A...

Ngày tải lên : 15/02/2014, 01:20

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Tài liệu Báo cáo khoa học: The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes doc

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx