Tài liệu Báo cáo khoa học: Integrase of Mason–Pfizer monkey virus doc

... characteri- zation of integrases of these viruses. Here we present characterization of the integrase of M-PMV and its functional and structural comparison with integrases of other retroviruses. The M-PMV integrase ... nonspecific nuclease activity of retroviral integrases is not known. Analysis of the sequence of M-PMV integrase and a comparison with other integrases The...

Ngày tải lên: 19/02/2014, 16:20

... covalent modification cycle. Doc S1B. Amount of sequestration in covalent modifi- cation cycles. Doc S1C. Models of double-phosphorylation and sequestration. Doc S1D. Model of MAPK cascade with sequestration and ... expressed the response of the active fraction to a change of the kinase concentration as a function of the concentra- tions of the two forms ([T] and [T*]) and t...

Ngày tải lên: 19/02/2014, 07:20

... ydrolysis of a cylamino-acid intermediates in amino- acid biosynthesis (DapE and A rgE), and many ORFs of as yet unknown function. Representatives of the family are found in all domains of life. ... 445 Structure of peptidase T from Salmonella typhimurium Kjell Ha Ê kansson* and Charles G. Miller Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL,...

Ngày tải lên: 21/02/2014, 03:20

... cost of semantic and linguistic flexibility. However, the loss of flexibility appears to be not much greater than the con- straints imposed by the grammar and semantics of the sublanguage of ... and others. Semantic analysis of a sample of natural text stock reports discloses that a hierarchy of approximately forty message classes accounts for nearly all of the semantic...

Ngày tải lên: 21/02/2014, 20:20

... Histograms of the height differences between the top of SERCA and the surface of the membrane. Statistical section analy- ses of SERCA were performed with the data obtained in the pres- ence of (A) ... period of observation in the presence of both ATP and Ca 2+ were excluded from the following analyses. Visual characteristics of the Albers–Post scheme The number of peaks (i....

Ngày tải lên: 14/02/2014, 14:20

... the inhibition of CYP activity observed in the absence of changes in protein expression in rabbit he- patocytes [22]. ROS indirectly reduced the activity of selected isoforms of CYP by inducing ... recognition of pathogen invasion and a facili- tation of the body’s subsequent immune responses [27]. The stimulation of these receptors activates inflamma- tory responses characterize...

Ngày tải lên: 14/02/2014, 18:20

... only after partial unfold- ing of the a-helix from the body of the b-sheet (Fig. 2C). Possible role of domain-swapping in the ‘off-pathway folding’ (OFF) model The OFF model for amyloid formation ... our understanding of the importance of different parts of the molecule and their flexibility in the process of amy- loid fibril formation often results more from a struc- tural analys...

Ngày tải lên: 14/02/2014, 18:20

... solu- tion of ThT and the fluorescence intensity of the solu- tion was measured at 482 nm. Figure 4A shows the kinetics of aggregation of a-synuclein in the presence of 100 lm MPTP and the effect of 50 ... measurement of ThT fluorescence would be an important probe for characterization of the nature of the aggregates. Char- acteristic sigmoidal curves of amyloid-type aggrega...

Ngày tải lên: 14/02/2014, 19:20

... deamination [30]. The lack of oxida- tion of 1 mm glutamate in the presence of 5 mm succinate can be demonstrated by a complete lack of effect of rotenone on recordings of membrane poten- tial from ... pore (PTP) [1,2], is of a sufficient size (cut-off of $ 1.5 kDa) to allow the pas- sage of solutes and water, which may also result in rupture of the outer membrane. The iden...

Ngày tải lên: 14/02/2014, 19:20

... represents one of the most successful human pathogens, inducing severe clinical symptoms only in a small subset of individuals, mirroring a highly balanced degree of co-evolution of H. pylori and humans. ... locations of infected target cells, which may have an important impact on the multistep pathogene- sis of H. pylori. The high number of binding partners also reflects the int...

Ngày tải lên: 14/02/2014, 19:20