... belonging t o class I of the superfamily of bacterial, fungal, and plant heme peroxidases. In Fig. 5 the simplified inferredFITCHtree, is presented, and in Fig. 6 the same tree in a simplified ... feature in this region. The iron of the prosthetic heme group is invariantlyco-ordinated by the a bove essential proximal h istidine(Fig. 4A,C,D). However, in all C-domains of catalase– peroxidases, ... vent in the g ene f or catalase–peroxid aseoccurred in the later phase of evolution, in which the indi-vidual specificities of the peroxidase families distinguishedwere already formed. Evidence...