Tài liệu Báo cáo khoa học: Arginine ethylester prevents thermal inactivation and aggregation of lysozyme pptx

... equation and determined the apparent T m . Results Thermal inactivation and aggregation of lysozyme in the presence of additives Figure 1 s hows the thermal inactivation and aggregation of lysozyme ... presence of NaCl suggest that the molecular mechanism of ArgEE in preventing thermal inactivation and aggregation is different from that of Arg. Therm...

Ngày tải lên: 19/02/2014, 16:20

... regulation of growth and differentiation in eukaryotic cells [1,82]. Despite profound improvements in our understanding of the molecular and cellular mechanisms of action of the Ras proteins, the expanding ... acti- vation of oncogenes, silencing of tumor suppressor genes and inactivation of DNA repair systems are a result of both genetic and epigenetic abnormalities...

Ngày tải lên: 18/02/2014, 14:20

... and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature 381, 335–341. 25 Suzuki M, Youle RJ & Tjandra N (2000) Structure of bax. Coregulation of dimer formation and ... the help of the CDPro software package, which contains three commonly used programs: selcon3, contin ⁄ ll and cdsstr [42,43]. This software allows the use of different reference s...

Ngày tải lên: 19/02/2014, 07:20

... minireview will focus on the cellular and molecular biology of PAI-2 and highlight some of the most recent findings on the role and impressive pattern of regulation of this enigmatic protease inhi- bitor. ... infection Cancer A number of in vivo studies have assessed the prognos- tic relevance of tumour- and stromal-derived PAI-2 in the metastatic spread of cancer of th...

Ngày tải lên: 20/02/2014, 02:21

... ª 2011 FEBS MINIREVIEW TEC family kinases in health and disease – loss -of- function of BTK and ITK and the gain -of- function fusions ITK–SYK and BTK–SYK Alamdar Hussain 1,2, *, Liang Yu 1,3, *, ... missing data. The phenotype of XLA and the potential of BTK and ITK inhibitors The outcome of defective BTK signaling in humans has been described previously in detail [26,27]...

Ngày tải lên: 14/02/2014, 18:20

... profibrinolytic consequences: enhancement of plasminogen activation, protection of plasmin from its inhibitor a 2 -antiplasmin and enhancement of the proteolytic activity of cell-bound plasmin [13,51]. ... levels of plasminogen activation and malignancy [46,52]. Higher expression levels of uPA and ⁄ or plasminogen activator inhibitor-1 (PAI-1) in tumor tissues correlate with...

Ngày tải lên: 14/02/2014, 19:20

... [19], and NMR spectroscopic data of p25a homologs from mice, Caenorhabditis elegans and humans [20–22] demon- strate a folded central core and unfolded N- and C-ter- minal extensions of  45 and ... of all three transporters [10,23,24]. Table 1 shows that p25a selectively stimulates uptake via DAT Table 1. Determination of V max and K m for DAT, NET and SERT in the prese...

Ngày tải lên: 14/02/2014, 21:20

... (starch and soluble car- bohydrates) during that time period of cold exposure. Effect of cold exposure on levels of soluble carbohydrates and starch Contents of leaf starch, sucrose, hexoses and ... modelling and simulation of cold-induced metabolic reprogramming indicated major differences in the rates of interconversion between the pools of hexoses and sucrose, as we...

Ngày tải lên: 14/02/2014, 22:20

... roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases, and discuss the possibility that both could func- tion as molecular targets for the prevention and treatment of obesity ... focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obes- ity and related metabolic diseases, and discuss whether these ANGPTLs could be targets for the prevention and trea...

Ngày tải lên: 14/02/2014, 22:20

... chan- nel that divides a pair of acidic lobes, one of which is composed of residues from the SET-I region and the other of residues from the SET-C and post-SET regions. Lysine 4 of histone H3 is inserted ... peptide from the Win motif of MLL1 bound to the WD40 repeat protein, WDR5 [24,25] and the C-terminal SET domain in the presence and absence of histone peptides and...

Ngày tải lên: 16/02/2014, 14:20