... light on the function of this interaction in the in vivo situation.By in uencing the duration of the Ca2+signal of ORs in the cilia of the sensory neurons, MUPP1 couldhave a strong in uence on ... 30% of receptors contain putative PDZbinding motifs in their C-termini, following the previ-ously outlined rules of binding [16]. PDZ domains1 + 2 of MUPP1 indeed showed direct interactionwith ... phosphorylation, ultimately result-ing in deactivation of the channel [12,29,30]. On the other hand, in contrast to the findings of the presentstudy, MUPP1 was shown to prolong the duration of GABABreceptor...