... activation of the protein kinase B survival pathway [31], p53 activa-tion [32], induction of the serum- and glucocorticoid-inducible kinase Sgk [33], expression of the heat shock protein Hsp70 [34] and ... summarizes recent progress in the understanding of howosmosensing and osmosignaling integrate into the overall context of growthfactor signaling and the execution of apoptotic programs.AbbreviationsEGF, ... involved in the regulation of metabolism, gene expression and the susceptibilityto different kinds of stress [6]. For example, the inhibi-tion of autophagic proteolysis by insulin, glutamine and ethanol...