Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc

... to the formation of cavities, one in the hydrophobic core (M88V) and the other in the protein–RNA interaction (T45S), decrease the stability of the capsid. Our findings illuminate the role of packing ... different from those of other simple icosahedral viruses [13]. The main chain of the protein subunit folds into a five stranded antiparallel b-sh...

Ngày tải lên: 19/02/2014, 12:20

... euge- nin, indicating that eugenin is indeed acting through CCK 2 receptors. To further investigate the interaction of eugenin with CCK 2 receptors, we investigated the effect of eugenin on lymphocyte ... as stimulation of the proliferation of lymphocytes, activa- tion of CCK receptors stimulate production of inter- leukins and secretion of immunoglobulins on the mucos...

Ngày tải lên: 19/02/2014, 16:20

... margin values of outputs given by the clas- sifier during the parsing process. All the sentences in the pool are processed by the current parser. We cannot simply split the sentences in the pool into labeled ... parser and a tool for the av- eraged perceptron in C++ and used them for ex- periments. We wrote the main program of active learning and some addition...

Ngày tải lên: 20/02/2014, 04:20

... We initialize the sampler by randomly as- signing each string in the training corpus a random tree generated by the grammar. Then we randomly select a string to resample, and sample a parse of ... shown in Figure 1. In this grammar and the grammars below, under- lining indicates an adapted nonterminal. Phoneme is a nonterminal that expands to each of the 50 dis- tinct...

Ngày tải lên: 20/02/2014, 09:20

... presented in one of four colors indicating that they: 1. are not part of an NP either in the truth or in the output of the person's rule set 2. consist of an NP both in the truth and in the ... recall vs. the number of appearances in the training set of each tag sequence for the machine and the mean of the top 3 students is shown in...

Ngày tải lên: 20/02/2014, 19:20

... takes as input a sentence and a context-free grammar and produces as output a chart like that below, indicating the starting point and ending point of each phrase in the input string. lnput~ ... of/ d/before/y /in didyou (5b) Reduction of unstressed/u/to schwa in) ,~u (5c) Flapping of intervocalic /t/ in hit. it (5d) Reduction of schwa and devoicing of/ u /...

Ngày tải lên: 21/02/2014, 20:20

... be nominative singular- masculine, and den Mann can only be accusative masculine-singular. There is thus only one pos- sible interpretation in which the dog is the biter and the man is being bitten, ... illustrated in the top of Figure 1. This Fig- ure shows the search tree of a small grammar when parsing the utterance Die Kinder gaben der Lehrerin die Zeichnung ( the...

Ngày tải lên: 22/02/2014, 03:20

... PPARc target genes affects the protein degradation, destabilizing the Akt-1 protein. In addition, the AMP-activated protein kinase pathway can affect Akt-1 protein levels in the cell [39]. It ... is involved in the suppression of cell proliferation and promotion of apoptosis in endothelial and tumor cells [20–22]. PPARc is also implicated in leptin-induced adipoc...

Ngày tải lên: 16/02/2014, 09:20

... further increase of Neu2 activity was observed during myotube hypertrophy obtained in the presence of IGF-1; more- over, the effects of IGF-1 were considerably reinforced in the presence of IGF-1 ... Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on p...

Ngày tải lên: 19/02/2014, 06:20

... sorbic, benzoic and propionic acid [7] and fail to adapt to such stress conditions in the absence of Pdr12p. Moreover, recent data indicate the involvement of Pdr12p in the export of by-products of amino-acid ... at the C-terminus. The mid- dle homology region (MHR) bridging the DNA-bind- ing and the activation domain may control the activity or specificity o...

Ngày tải lên: 19/02/2014, 00:20