Tài liệu Báo cáo khoa học: Unusual metal specificity and structure of the group I ribozyme fromChlamydomonas reinhardtii23S rRNA pptx

... the similar affinities of EDTA for Mn 2+ and Fe 2+ , and the fact that Mn 2+ is in large excess in these reactions [34]. Discussion Kinetic analysis of Mn 2+ inhibition The group I ribozyme literature ... less internalized) than are those of other group I ribozymes studied to date. It is also intriguing that the kinetic data implicate the G binding site as playing...

Ngày tải lên: 19/02/2014, 07:20

... acyltransferases with different properties and tissue distribution. CPT1a is enriched in the liver and has been heavily studied due to the key role of beta-oxidation in gluconeogenesis Signaling mediators in the ... this is the close correlation with the hypothalamic levels of orexigenic and anorexigenic neuropeptide expression during fast- ing and refeeding. A detailed...

Ngày tải lên: 14/02/2014, 22:20

... char- acteristics, a significant understanding of the enzymes involved in the detoxification of phytoalexins, includ- ing their substrate specificity as well as the molecular mechanisms of detoxification, is ... (2006) Toward the control of Leptosphaeria maculans: Design, synthesis, biological activity, and metabolism of potential detoxification inhibitors of the crucifer p...

Ngày tải lên: 18/02/2014, 14:20

... 50% of the isoforms are shown in black and grey, respectively. Histidine residues involved in zinc binding in the catalytic site are indicated by a ‘Z’; important amino acids involved in the ... background noise). This is the first report of tissue-specific expression of cytosolic CAs in a nonvertebrate species. Such a pro- tein is essential for the symbiotic association of...

Ngày tải lên: 18/02/2014, 16:20

... (reaction 1). The subsequent oxidation transforms the sulfhydryl group into the sulfinic and sulfonic species (reaction 2). The reactivities of these groups and the close proximity to the ATP binding ... this stage, the addition of 3 mm ATP and 3 mm Mg 2+ did not shift the maximum emission wavelength, but progressively increased the emission intensity, indicating...

Ngày tải lên: 18/02/2014, 17:20

... some indispensable cofactors (i. e. phospholipids) for crystallization were integrated with the four subunits of complex II, and might have been discarded following further purification. Initial screening ... porcine heart from the slaughterhouse was sheared into pieces and immediately immersed in liquid nitrogen. One hundred milligrams of heart tissue was picked up and milled in...

Ngày tải lên: 19/02/2014, 02:20

... natural I- III, II-IV; mispaired ÔnestedÕ I- IV, II-III and mispaired ÔdiscreteÕ I- II, III-IV, Fig. 3E). It was possible to achieve the desired alignments with either order of loop formation (smaller ... information for ImIIA and Vc1.1, ImII, GIC and PIA, each of which was identified by prediction from a genomic DNA clone [7–10,22]. Comparison of the peptide sequences GID,...

Ngày tải lên: 19/02/2014, 12:20

... Linguistics Beefmoves: Dissemination, Diversity, and Dynamics of English Borrowings in a German Hip Hop Forum Matt Garley Department of Linguistics University of Illinois 707 S Mathews Avenue Urbana, IL 61801, ... anglicism seems to become increasingly undesirable–after all, if everyone is using it, it loses its capacity to distinguish in -group members (con- sider, e.g., the wides...

Ngày tải lên: 19/02/2014, 19:20

...

Ngày tải lên: 20/02/2014, 18:20

... activity [10,17]. Within the large recombinant protein, t he exposure and/ or the environment of t his basic cluster of amino acids might be different, even if the high hydrophilic nature of this domain likely ... not signi®cantly reduced in the presence of the excess of t he Tat peptide, in keep ing with separate internalization pathways. Internalization of the Tat±G...

Ngày tải lên: 21/02/2014, 03:20