... composition, on the one hand [91,172–178] and the DNA- methylation status [26–28] of many genes (e.g. FAS and CLU), on the other hand. EGCG can bind to GpC-rich regions of DNA. Radiation can damage the respective ... [2,6,22,59–71], because the presence of methyl groups on DNA affect the structure of DNA and the interaction of other proteins and enzymes with local nucleosomes [2,60]. Methylation of DNA (MeCpG-) ... correlation between the depletion of H3K4Me2 in the regions of DNA methylation. Conversely, the level of H3K4Me2 remains high in the unmethylated DNA regions regardless of the presence of RNA Pol II....