Tài liệu Báo cáo khoa học: DNA strand exchange activity of rice recombinase OsDmc1 monitored by fluorescence resonance energy transfer and the role of ATP hydrolysis pptx
... Journal compilation ª 2006 FEBS DNA strand exchange activity of rice recombinase OsDmc1 monitored by fluorescence resonance energy transfer and the role of ATP hydrolysis Chittela Rajanikant 1 , ... unveil the sta- tus of physical union and separation of complementary strands during renaturation and strand exchange, respectively, and th...
Ngày tải lên: 19/02/2014, 07:20
... composition, on the one hand [91,172–178] and the DNA- methylation status [26–28] of many genes (e.g. FAS and CLU), on the other hand. EGCG can bind to GpC-rich regions of DNA. Radiation can damage the respective ... [2,6,22,59–71], because the presence of methyl groups on DNA affect the structure of DNA and the interaction of other proteins and enzymes w...
Ngày tải lên: 18/02/2014, 14:20
... conducted with Dam of Escherichia coli hints at the answers to these questions. Dam belongs to the a group of methyl- transferases and transfers a methyl group to the N6 position of the adenine in ... because most of the spots were methylated and the number of informative land- mark spots was insufficient for matching the real and virtual RLGS patterns. There were...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khoa học: DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner pptx
... in the genome of living cells is naturally stochastic on the one hand, and influenced by the actual structural and functional state of the given chromatin domain on the other. Moreover, some of the ... cisplatin IACs within the p53DBSs due to the occurrence of the GG, AG and ⁄ or GNG motifs, the stronger the inhibition of the p53 sequence-specific DNA...
Ngày tải lên: 19/02/2014, 05:20
Tài liệu Báo cáo khoa học: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor pdf
... dependence of the inhibitory activity of soluble forms of HAI-1 and HAI-2 against the protease activity of TMPRSS13. (A) Schematic representation of the structure of the full-length HAI-1 (1) and soluble ... vitro, and the pro-HGF converting activity of TMPRSS13 was inhibited by NK1. The two-chain form of HGF exhibited biological activity, assessed...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
... the formation of the MT1-MMP–furin complex; therefore, disruption of the interaction between GRASP55 and furin should perturb the activation of pro-MT1-MMP and reduce MT1-MMP activity at the cell surface. ... by annealing overlapping oligonucleotides and ‘filling up’ the single strand regions with KOD DNA polymerase (2.5 units; Merck Biosciences Ltd, Nottingham,...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Changes in purine specificity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2 pptx
... spe- cificity. The expectation of this hypothesis was fulfilled by construct I. A cyaB1 tandem GAF domain with replacement of this segment by the rPDE2 region, which comprised only 23% of the residues of the cyaB1 ... cGMP over cAMP as a ligand [12]. Taken together the b1–b3 region of the tandem GAF domain appears to be a major determinant of purine selection. The...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khoa học:Insulin-like growth factor 1 signaling regulates cytosolic sialidase Neu2 expression during myoblast differentiation and hypertrophy doc
... inhibitor of PI3 kinase activ- ity. In addition, the inhibition of mTOR activity was achieved in the presence of 5 ngÆmL )1 rapamycin, as revealed by the absence of the phosphorylated form of p70S6K. ... pre- vented by treatment with LY. The block of differenti- ation was obtained even in the presence of rapamycin (data not shown), an inhibitor of mTOR activ...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: "An ERP-based Brain-Computer Interface for text entry using Rapid Serial Visual Presentation and Language Modeling" ppt
... a diagram of the timing of the presentation of stimuli. We define a sequence to be a randomly-ordered set of all the letters (and the space and backspace symbols). The letters are randomly ordered ... ex- cept the backspace) is added to the end of the list of previously-detected symbols, the user is able to take a break of indefinite length, and then the s...
Ngày tải lên: 20/02/2014, 05:20
Tài liệu Báo cáo khoa học: Transient DNA ⁄ RNA-protein interactions docx
... nature of the interaction in solution (Fig. 1). The recent assignment of the NMR spectrum of the PCNA ring [6,7] provides the basis for solution studies of its interactions with DNA and other proteins ... structure of the ribosome of Thermus thermophilus (Protein Data Bank entries 1GIX and 1GIY) is shown, with the rRNA molecules represented by thin coils, th...
Ngày tải lên: 14/02/2014, 19:20